Patents by Inventor William M. McGEE

William M. McGEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for mass spectrometric based characterization of biological molecules
    Patent number: 10458994
    Abstract: Applications of ion-ion reaction chemistry are disclosed in which proton transfer reactions (PTR) combined with higher-collision-energy dissociation (HCD) are used to (1) simplify complex mixture analysis of samples introduced into a mass spectrometer, and (2) improve resolution and sensitivity for the analysis of large proteins in excess of 50 kDa by removing charge, reducing the collisional cross section, and, in several cases, enhancing the sequence coverage obtained.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: October 29, 2019
    Assignee: THERMO FINNIGAN LLC
    Inventors: William M. McGee, Helene L. Cardasis
  • Methods for Mass Spectrometric Based Characterization of Biological Molecules
    Publication number: 20190004062
    Abstract: Applications of ion-ion reaction chemistry are disclosed in which proton transfer reactions (PTR) combined with higher-collision-energy dissociation (HCD) are used to (1) simplify complex mixture analysis of samples introduced into a mass spectrometer, and (2) improve resolution and sensitivity for the analysis of large proteins in excess of 50 kDa by removing charge, reducing the collisional cross section, and, in several cases, enhancing the sequence coverage obtained.
    Type: Application
    Filed: August 21, 2018
    Publication date: January 3, 2019
    Inventors: William M. McGEE, Helene L. CARDASIS
  • Methods for mass spectrometric based characterization of biological molecules
    Patent number: 10101335
    Abstract: Applications of ion-ion reaction chemistry are disclosed in which proton transfer reactions (PTR) combined with higher-collision-energy dissociation (HCD) are used to (1) simplify complex mixture analysis of samples introduced into a mass spectrometer, and (2) improve resolution and sensitivity for the analysis of large proteins in excess of 50 kDa by removing charge, reducing the collisional cross section, and, in several cases, enhancing the sequence coverage obtained.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: October 16, 2018
    Assignee: Thermo Finnigan LLC
    Inventors: William M. McGee, Helene L. Cardasis
  • Methods for Mass Spectrometric Based Characterization of Biological Molecules
    Publication number: 20170205424
    Abstract: Applications of ion-ion reaction chemistry are disclosed in which proton transfer reactions (PTR) combined with higher-collision-energy dissociation (HCD) are used to (1) simplify complex mixture analysis of samples introduced into a mass spectrometer, and (2) improve resolution and sensitivity for the analysis of large proteins in excess of 50 kDa by removing charge, reducing the collisional cross section, and, in several cases, enhancing the sequence coverage obtained.
    Type: Application
    Filed: January 13, 2017
    Publication date: July 20, 2017
    Inventors: William M. McGEE, Helene L. CARDASIS