Patents by Inventor William M. Wuest

William M. Wuest has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibacterial compounds
    Patent number: 11690824
    Abstract: The present application provides compounds of formula: Methods of using these compounds for killing bacterial growth and treating bacterial infections are also provided.
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: July 4, 2023
    Assignees: The General Hospital Corporation, Rhode Island Hospital, A Lifespan-Partner, Emory University
    Inventors: Frederick M. Ausubel, Wooseong Kim, Eleftherios Mylonakis, William M. Wuest
  • ANTIBIOTIC COMPOUNDS
    Publication number: 20220324796
    Abstract: The present application provides compounds and methods for treating bacterial infections, including bacterial infections caused by MRSA.
    Type: Application
    Filed: June 11, 2020
    Publication date: October 13, 2022
    Inventors: Frederick M. Ausubel, Wooseong Kim, Eleftherios Mylonakis, William M. Wuest
  • Antibiotic Compounds
    Publication number: 20220095614
    Abstract: The present application provides compounds and methods of treating bacterial infection, including bacterial infection caused by P. acnes.
    Type: Application
    Filed: November 23, 2021
    Publication date: March 31, 2022
    Inventors: Frederick M. Ausubel, Wooseong Kim, Eleftherios Mylonakis, William M. Wuest
  • Antibiotic compounds
    Patent number: 11278025
    Abstract: The present application provides compounds and methods of treating bacterial infection, including bacterial infection caused by P. acnes.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: March 22, 2022
    Assignees: The General Hospital Corporation, Rhode Island Hospital, A Lifespan-Partner, Temple University-Of The Commonwealth System of Higher Education
    Inventors: Frederick M. Ausubel, Wooseong Kim, Eleftherios Mylonakis, William M. Wuest
  • Polycationic Amphiphiles as Antimicrobial Agents and Methods Using Same
    Publication number: 20210403430
    Abstract: The present invention includes novel polycationic amphiphilic compounds useful as antimicrobial agents. The present invention further includes methods useful for removing microorganisms and/or biofilm-embedded microorganisms from a surface. The present invention further includes compositions and methods useful for preventing or reducing the growth or proliferation of microorganisms and/or biofilm-embedded microorganisms on a surface.
    Type: Application
    Filed: September 7, 2021
    Publication date: December 30, 2021
    Inventors: William M. Wuest, Kevin P.C. Minbiole
  • Polycationic amphiphiles as antimicrobial agents and methods using same
    Patent number: 11111216
    Abstract: The present invention includes novel polycationic amphiphilic compounds useful as antimicrobial agents. The present invention further includes methods useful for removing microorganisms and/or biofilm-embedded microorganisms from a surface. The present invention further includes compositions and methods useful for preventing or reducing the growth or proliferation of microorganisms and/or biofilm-embedded microorganisms on a surface.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: September 7, 2021
    Assignees: Temple University-Of The Commonwealth System of Higher Education, Villanova University
    Inventors: William M. Wuest, Kevin P. C. Minbiole
  • Antibacterial Compounds
    Publication number: 20210251958
    Abstract: The present application provides compounds of formula: Methods of using these compounds for killing bacterial growth and treating bacterial infections are also provided.
    Type: Application
    Filed: April 10, 2019
    Publication date: August 19, 2021
    Inventors: Frederick M. Ausubel, Wooseong Kim, Eleftherios Mylonakis, William M. Wuest
  • BISPHENOL COMPOUNDS
    Publication number: 20200375949
    Abstract: The present disclosure provides compounds of formula (I) or salts thereof, wherein R1-R10 and x are defined herein; compositions containing these compounds; methods of inhibiting, reducing, or ameliorating bacterial growth on a substrate using these compound; and products such as dental care products, soaps, antibacterial products, and plastics comprise one or more compounds described herein.
    Type: Application
    Filed: November 21, 2018
    Publication date: December 3, 2020
    Inventors: Marisa C. KOZLOWSKI, Young Eun LEE, Thomas PANIAK, Cristian OCHOA, William M. WUEST, Amy E. SOLINSKI
  • Polycationic Amphiphiles as Antimicrobial Agents and Methods Using Same
    Publication number: 20200277263
    Abstract: The present invention includes novel polycationic amphiphilic compounds useful as antimicrobial agents. The present invention further includes methods useful for removing microorganisms and/or biofilm-embedded microorganisms from a surface. The present invention further includes compositions and methods useful for preventing or reducing the growth or proliferation of microorganisms and/or biofilm-embedded microorganisms on a surface.
    Type: Application
    Filed: October 26, 2017
    Publication date: September 3, 2020
    Inventors: William M. Wuest, Kevin P.C. Minbiole
  • Antibiotic Compounds
    Publication number: 20200190009
    Abstract: The present application provides compounds and methods of treating bacterial infection, including bacterial infection caused by P. acnes.
    Type: Application
    Filed: May 17, 2018
    Publication date: June 18, 2020
    Inventors: Frederick M. Ausubel, Wooseong Kim, Eleftherios Mylonakis, William M. Wuest
  • Promysalin analogues and methods of use thereof
    Patent number: 10647671
    Abstract: The present invention includes novel analogs of promysalin useful in preventing or treating a microbial infection. The present invention also includes methods preventing or treating a microbial infection in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of the invention.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: May 12, 2020
    Assignee: Temple University—Of The Commonwealth System of Higher Education
    Inventor: William M. Wuest
  • Novel Promysalin Analogues and Methods of Use Thereof
    Publication number: 20190161444
    Abstract: The present invention includes novel analogs of promysalin useful in preventing or treating a microbial infection. The present invention also includes methods preventing or treating a microbial infection in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of the invention.
    Type: Application
    Filed: April 18, 2017
    Publication date: May 30, 2019
    Inventor: William M. WUEST
  • Substituted polycationic multi-quaternary ammonium salts as antimicrobial agents
    Patent number: 10301254
    Abstract: The present invention includes polycationic amphiphilic compounds of formula VII useful as antimicrobial agents. The present invention further includes novel polymers of polycationic amphiphilic compounds useful as antimicrobial agents. The present invention further includes methods useful for removing microorganisms and/or biofilm-embedded microorganisms from a surface. The present invention further includes compositions and methods useful for preventing or reducing the growth or proliferation of microorganisms and/or biofilm-embedded microorganisms on a surface.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: May 28, 2019
    Assignee: Temple University—Of The Commonwealth System of Higher Education
    Inventors: William M. Wuest, Kevin P. C. Minbiole
  • POLYCATIONIC AMPHIPHILES AND POLYMERS THEREOF AS ANTIMICROBIAL AGENTS AND METHODS USING SAME
    Publication number: 20180111893
    Abstract: The present invention includes novel polycationic amphiphilic compounds useful as antimicrobial agents. The present invention further includes novel polymers of polycationic amphiphilic compounds useful as antimicrobial agents. The present invention further includes methods useful for removing microorganisms and/or biofilm-embedded microorganisms from a surface. The present invention further includes compositions and methods useful for preventing or reducing the growth or proliferation of microorganisms and/or biofilm-embedded microorganisms on a surface.
    Type: Application
    Filed: April 22, 2016
    Publication date: April 26, 2018
    Inventors: William M. Wuest, Kevin P.C. Minbiole, Deanna L. Barbay