Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.

Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.

Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.

Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.

Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.

Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.

Abstract: This disclosure provides methods and compositions for biomolecule corona analysis of biofluids. A biofluid may be contacted with a nanoparticle to form a biomolecule corona, and the composition of the resulting corona may be analyzed. Also provided are methods of preparing a biofluid for corona analysis by serial interrogation.

Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.

Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.

Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.

Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.

Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.

Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.

Abstract: This disclosure provides methods and compositions for biomolecule corona analysis of biofluids. A biofluid may be contacted with a nanoparticle to form a biomolecule corona, and the composition of the resulting corona may be analyzed. Also provided are methods of preparing a biofluid for corona analysis by serial interrogation.

Abstract: Disclosed embodiments include a small form-factor pluggable (SFP) optical transceiver having optical time domain reflectometer functionality. A monitor processor is included in the transceiver to report link status and failure information to a cloud-based monitoring application. When a fiber optic link is established, the monitor processor remains idle to reduce power consumption by the transceiver. Upon failure of the link, the monitor processor sends a failure report to the monitoring application which can use the data to alert operators to presence and location of optical fiber breaks in the network.

Abstract: Disclosed embodiments include a small form-factor pluggable (SFP) optical transceiver having optical time domain reflectometer functionality. A monitor processor is included in the transceiver to report link status and failure information to a cloud-based monitoring application. When a fiber optic link is established, the monitor processor remains idle to reduce power consumption by the transceiver. Upon failure of the link, the monitor processor sends a failure report to the monitoring application which can use the data to alert operators to presence and location of optical fiber breaks in the network.

Abstract: An out-of-band Domain Name System (DNS) security technique uses a cryptographic blockchain for securing and validating DNS data in a chain of custody that exists outside the DNS namespace, allowing validated access to cached DNS information without requiring real-time access to root servers.

Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.

Abstract: A method of authorizing a negotiable instrument includes automatically receiving a request for the instrument, identity data identifying a requester, and a location of a requester. If the location is within location range for the identity data, a verification code is transmitted to the client. An input code is received from a personal mobile device at a location. If the input code matches the verification code and the device is near the requester, a reference code of the negotiable instrument is transmitted to the client and is stored. A method of performing a financial transaction indicated by the instrument includes automatically receiving the reference code, receiving identifying data of a bearer of the negotiable instrument; determining whether the received identifying data correspond to a request for the instrument; and, if so, producing a transaction record corresponding to the request and invalidating the reference code. Systems are also described.

Abstract: An out-of-band Domain Name System (DNS) security technique uses a cryptographic blockchain for securing and validating DNS data in a chain of custody that exists outside the DNS namespace, allowing validated access to cached DNS information without requiring real-time access to root servers.