Patents by Inventor William Marc MATON

William Marc MATON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF BRUTON'S TYROSINE KINASE INHIBITORS
    Publication number: 20250163076
    Abstract: The present disclosure is directed to methods of synthesizing a compound of Formula (I), where the R groups are defined herein, and to methods of synthesizing a compound of Formula (II). Some aspects of the present disclosure is directed to converting the compound of Formula (II) into its P form.
    Type: Application
    Filed: February 17, 2023
    Publication date: May 22, 2025
    Inventors: Ngoc Duc TRAN, Christos XIOURAS, Edward CLEATOR, William Marc MATON, Thomas Joachim Landewald RAMMELOO, Philippe FERNANDES, Jean-Pierre A BONGARTZ, Duy Chi Trung CAO, Matthew Allan HORWITZ, Xavier Jean-Marie JUSSEAU, Sébastien Francois-Emmanuel LEMAIRE, Bertrand SCHWEITZER-CHAPUT
  • MACROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME
    Publication number: 20250082793
    Abstract: The present invention is directed to the preparation of key intermediates and synthesis of compounds (macrocyclic compounds) and pharmaceutically acceptable salts thereof, immunoconjugates, radioimmunoconjugates thereof, pharmaceutical compositions containing said compounds and immunoconjugates, radioimmunoconjugates thereof.
    Type: Application
    Filed: November 8, 2022
    Publication date: March 13, 2025
    Inventors: Edward CLEATOR, William Marc MATON, Rhys SALTER
  • SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES
    Publication number: 20230142285
    Abstract: The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, including but not limited to leukemia, myelodysplastic syndrome (MDS), and myeloproliferative neoplasms (MPN); and diabetes.
    Type: Application
    Filed: December 17, 2020
    Publication date: May 11, 2023
    Inventors: Wei CAI, Xuedong DAI, Oliver Alexis Georges QUEROLLE, Johannes Wilhelmus John F. THURING, Yingtao LIU, Lianzhu LIU, Yanping XU, Liqiang FU, Ming LI, Lichao FANG, Xianguin DENG, Qiwu ZHAO, Kangying LI, Alicia Tee Fuay NG, Nicolas Freddy J. DARVILLE, Edward CLEATOR, Gregor Thomas URBANIETZ, William Marc MATON, Vineet PANDA