Patent number: 8242116
Abstract: A series of 6,7-dihydro[1,3]thiazolo[5,4-c]pyridin-4(5H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
Type:
Grant
Filed:
June 26, 2007
Date of Patent:
August 14, 2012
Assignee:
UCB Pharma S.A.
Inventors:
Rikki Peter Alexander, Pavandeep Singh Aujla, Karen Viviane Lucile Crépy, Anne Marie Foley, Richard Jeremy Franklin, Alan Findlay Haughan, Helen Tracey Horsley, William Mark Jones, Bénédicte Irma Léonce Frédérique Lallemand, Stephen Robert Mack, Trevor Morgan, Patrick Marie Ghislain Pasau, David Jonathan Phillips, Verity Margaret Sabin, George Martin Buckley, Kerry Jenkins, Benjamin Garfield Perry
Publication number: 20100137302
Abstract: A series of 6,7-dihydro[1,3]thiazolo[5,4-c]pyridin-4(5H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
Type:
Application
Filed:
June 26, 2007
Publication date:
June 3, 2010
Applicant:
UCB PHARMA S.A.
Inventors:
Rikki Peter Alexander, Pavandeep Singh Aujla, Karen Viviane Lucile Crepy, Anne Marie Foley, Richard Jeremy Franklin, Alan Findlay Haughan, Helen Tracey Horsley, William Mark Jones, Benedicte Irma Leonce Frederique Lallemand, Stephen Robert Mack, Trevor Morgan, Patrick Marie Ghislain Pasau, David Jonathan Phillips, Verity Margaret Sabin, George Martin Buckley, Kerry Jenkins, Benjamin Garfield Perry