Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.

Abstract: A slot type game with one or more dynamic paylines and/or dynamic payline modifiers includes a grid or matrix of symbols for which one or more symbol outcomes may be determined and presented. In embodiments with a dynamic payline, the slot type game also includes a payline determination for which a payline outcome may be determined and presented. The payline outcome may correspond to positions of symbols in the grid or matrix and may determine whether or not the corresponding symbols in the grid or matrix are winners. In embodiments with a dynamic payline modifier, the slot type game also includes a payline modifier for which a payline modifier outcome may be determined and presented. The payline modifier outcome may correspond to positions of symbols in one or more paylines and may determine whether or not the one or more paylines and/or symbols are modified.

Abstract: A user-controlled portable traffic control system comprises one or more traffic signal units and a wireless handheld remote-control unit. Each traffic signal unit provides instruction to approaching motorists via a segmented backlit display consisting of first and second message panels. The wireless handheld remote-control unit allows a user to communicate commands to the traffic signal units via a transceiver circuit. Additionally, the handheld remote-control unit includes an interface indicating system status information via a plurality of indicator lights corresponding to the traffic signal units. Each traffic signal unit is housed in a two-part collapsible rigid outer case with a mounting handle allowing for ease of transport and a versatile means of both mounting and transporting the system.

Abstract: A user-controlled portable traffic control system comprises one or more traffic signal units and a wireless handheld remote-control unit. Each traffic signal unit provides instruction to approaching motorists via a segmented backlit display consisting of first and second message panels. The wireless handheld remote-control unit allows a user to communicate commands to the traffic signal units via a transceiver circuit. Additionally, the handheld remote-control unit includes an interface indicating system status information via a plurality of indicator lights corresponding to the traffic signal units. Each traffic signal unit is housed in a two-part collapsible rigid outer case with a mounting handle allowing for ease of transport and a versatile means of both mounting and transporting the system.

Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.

Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.

Abstract: The present disclosure is directed to a spring arrangement for use in a drug delivery device and a drug delivery device including such a spring arrangement. The spring arrangement includes a clutch spring which is located axially interposed between a stationary housing component and an axially movable sleeve. The sleeve includes clutch features adapted to engage corresponding clutch features of a clutch element. The clutch spring biases the clutch features and the corresponding clutch features into engagement. The sleeve is coupled to a button such that upon actuation of the button the sleeve is translated against the bias of the clutch spring from a proximal position in which the sleeve is rotationally locked to the housing component into a distal position in which the sleeve is rotationally un-locked from the housing component. Upon release of the button the clutch spring translates the sleeve and the button into the proximal position.

Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing and at least two separate component parts, wherein for example at least one of these component parts performs a movement relative to the housing during dose setting and for example at least one of these component parts performs a movement relative to the housing during dose dispensing, and wherein the relative movement of the at least two separate component parts with respect to each other during dose setting differs from the relative movement of the at least two separate component parts with respect to each other during dose dispensing.

Abstract: A drive mechanism (4) for a drug delivery device comprising—a piston rod (14), —a trigger member (9) coupled with the piston rod (14) in such a manner that rotational movement between the piston rod (14) and the trigger member (9) is constrained in a first state, the trigger member (9) being elastically deformable in such a manner that the piston rod (14) is rotationally moveable with respect to the trigger member (9) in a second state, —a trigger button (10) being suitable for activating the deformation of the trigger member (9).

Abstract: The disclosure refers to a handheld injection device comprising a housing, a dose indicator positioned within and axially constrained to the housing and rotatable with respect to the housing during dose setting and during dose dispensing, a gauge element, which is at least partly interposed between the housing and the dose indicator, wherein the gauge element is axially guided within the housing and in threaded engagement with the dose indicator such that rotation of the dose indicator causes an axial displacement of the gauge element (80; 490). A contrast element having a first marking is provided and at least a region of the gauge element is provided with a second marking, with the first marking and/or the second marking being visible through a first window or aperture in the housing depending on the axial position of the gauge element within the housing.

Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.

Abstract: The present disclosure is directed to a drive sleeve with a hollow body having a ring of crown teeth with a first outer diameter forming a clutch interface at a first end and a thread extending on an outer surface of the body. The thread has a major diameter and a minor diameter, wherein the ring of crown teeth has at least two cavities. The at least two cavities extend on the outer surface of the body from the first end to the thread and defining a second outer diameter which is smaller than the major diameter of the thread. Further, some embodiments are directed to a drug delivery device with such a drive sleeve and a method for assembling a drug delivery device.

Abstract: A communication module is configured to obtain, from a first computing device associated with an energy receiver, an energy request. The energy request includes a location of the energy receiver and an amount of energy requested. A selection module is configured to generate a list of energy sources available to satisfy the energy request. The communication module is further configured to: transmit the list of energy sources to the first computing device for display; receive, from the first computing device, a selection of one energy source from the list of energy sources; and transmit, to the first computing device and a second computing device associated with the selected one energy source, a location at which the energy request is to be fulfilled. An energy transfer module is configured to selectively enable an electrical energy transfer from the selected one energy source to the energy receiver.

Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.

Abstract: A communication module is configured to obtain, from a first computing device associated with an energy receiver, an energy request. The energy request includes a location of the energy receiver and an amount of energy requested. A selection module is configured to generate a list of energy sources available to satisfy the energy request. The communication module is further configured to: transmit the list of energy sources to the first computing device for display; receive, from the first computing device, a selection of one energy source from the list of energy sources; and transmit, to the first computing device and a second computing device associated with the selected one energy source, a location at which the energy request is to be fulfilled. An energy transfer module is configured to selectively enable an electrical energy transfer from the selected one energy source to the energy receiver.

Abstract: A drive mechanism (1) for use in a drug delivery device (100) is provided. The drive mechanism (1) comprises a housing (10, 11, 12, 14, 15) with a proximal and a distal end and a piston rod (22) which is rotatable with respect to the housing (10, 11, 12, 14, 15). The drive mechanism (1) further comprises a nut member (31) which is selectively rotationally lockable with respect to the housing (10, 11, 12, 14, 15), wherein the drive mechanism (1) is switchable between a setting mode of operation and a dispensing mode of operation.

Abstract: A method for assembling a drive spring, especially into a drug delivery device includes rotating a component part to which the drive spring is attached in a first direction, followed by a rotation of the component part in the opposite direction and followed by attachment of a rotational stop. Further, the disclosure includes a drug delivery device for selecting and dispensing a number of user variable doses of a medicament, which device comprises a pre-charged drive spring.

Abstract: A drug delivery device for dispensing a dose of a liquid medicament with a rotationally driveable expelling mechanism adapted to expel the dose of the liquid medicament from a medicament container, a round torsional drive spring adapted to apply a driving torque to the rotationally driveable expelling mechanism when energized by an external strain, wherein the round torsional drive spring encloses an interior space of varying shape and/or extension according to the level of external strain applied to the round torsional drive spring, and at least one restraining element defining a number of rest surfaces to internally support the round torsional drive spring increasingly with the level of external strain applied thereto, can be improved by providing the rest surfaces with an outer shape as to essentially maintain the centre of the interior space throughout the entire variation in external strain applicable to the round torsional drive spring.

Abstract: The present disclosure relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device and to such a drug delivery device. The mechanism comprises a spring driven rotatable drive member, a rotatable driven member, a clutch rotationally coupling the driven member and the drive member in a coupled state and allowing relative clockwise and anti-clockwise rotation between the driven member and the drive member in a decoupled state, and a spring biasing the clutch into its coupled state and allowing relative axial movement between the drive member and the driven member into the decoupled state of the clutch against the bias of the spring.

Abstract: A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing having a tubular portion with an inner thread, a piston rod having a threaded portion and a distal end, and a bearing having a distal face and a proximal face. The bearing includes a retaining stem protruding from the proximal face. The piston rod includes a distal portion having an outer diameter which is smaller than the inner diameter of the inner thread of the tubular portion and comprising at its distal end at least one retaining clip engaging the retaining stem. The axial length of the tubular portion is smaller than or equal to the axial distance between the proximal face of the bearing disc and the distal end of the threaded portion of the piston rod. During manufacturing of the device, the retaining clip engages the retaining stem prior to the inner thread of the tubular portion engages with the threaded portion of the piston rod.