Abstract: Techniques for modulation and demodulation using near-Nyquist sampling operate using substantially band-limited signal. In modulating, the substantially band-limited signal is formed by filtering modulated symbol date to produce a complex sample stream having a bandwidth of less than the twice the associated symbol transmission rate and with a sample rate of less than twice the symbol rate. In demodulating, a substantially band-limited signal having a bandwidth of less than twice the associated symbol transmission rate is sampled at a sample rate of less than twice the symbol rate of the modulation.

Abstract: A method and system for maintaining communication of data in a communication link between a transmission site and a reception site during a momentary disruption of the communication link includes storage of data during the disruption, and optionally both prior to and subsequent to the disruption, to enable communication subsequently to the disruption. In one embodiment, data is stored over an interval of time longer than the disruption and centered on the disruption, and is scrambled prior to communication between the transmission site and the reception site. Unscrambling of the data in a received sequence and application of error-correction code to the received sequence regains information which would have been lost in the disruption. Use may also be made of buffers at both of the sites for saving data which was to be transmitted during the disruption, and communicating the data to the end-user buffer subsequent to the disruption.

Abstract: A valve apparatus that has a longitudinal axis therethrough comprises a valve seat member, a valve closure member, a fluid flow path, and a screening member. The valve seat member comprises a hollow bore and a first frustoconical contact surface. The valve closure member comprises a body and a second frustoconical contact surface that is adapted to seal against the first frustoconical contact surface. The valve closure member is movable along the longitudinal axis of the valve apparatus. The fluid flow path extends through the bore of the valve seat member and between the valve seat member and the valve closure member. This fluid flow path is closed when the second frustoconical contact surface is sealed against the first frustoconical contact surface. The screening member is attached to at least one of the valve closure member or the valve seat member, and screens particles from fluid passing through the fluid flow path when the valve closure member approaches the valve seat member.

Abstract: This invention relates to compositions and methods for the treatment of pathologies associated with intracellular polyamine dysregulation. In particular, the present invention provides compositions and methods involving mammalian polyamine oxidase (PAO) to treat cancer, cell damage, tissue damage caused by ischemia/reperfusion, inflammation, traumatic brain injury, stroke and tissue developmental disorders. Methods for diagnosis and prognosis of cancer and other diseases are also provided by the present invention.

Abstract: A method and system for maintaining communication of data in a communication link between a transmission site and a reception site during a momentary disruption of the communication link includes storage of data during the disruption, and optionally both prior to and subsequent to the disruption, to enable communication subsequently to the disruption. In one embodiment, data is stored over an interval of time longer than the disruption and centered on the disruption, and is scrambled prior to communication between the transmission site and the reception site. Unscrambling of the data in a received sequence and application of error-correction code to the received sequence regains information which would have been lost in the disruption. Use may also be made of buffers at both of the sites for saving data which was to be transmitted during the disruption, and communicating the data to the end-user buffer subsequent to the disruption.

Abstract: A modem, or a communication system, in its transmission section, has signal-formatting circuitry followed by circuitry for insertion of a sequence of pilot symbols into a sequence of data symbols outputted by the formatting circuitry. Placement of the insertion circuitry after the formatting circuitry permits a variety of formatting options without effecting the sequence of pilot symbols that serves as a time reference useful in detection of a signal transmitted by the modem. The reception section of the modem is equipped correspondingly to process a received composite signal of data symbols having a prescribed format and a sequence of pilot symbols. The reception section extracts the sequence of pilot symbols from the composite signal, and employs the pilot symbols to develop a time base for operation of circuitry for decoding the format of the received composite signal to extract data from the composite signal.