Patents by Inventor William Michael Nichols

William Michael Nichols has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for stabilizing phenylephrine
    Patent number: 8323695
    Abstract: The present invention relates to a process for stabilizing phenylephrine including drying an acidic solution of phenylephrine and pharmaceutical compositions including stabilized phenylephrine.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: December 4, 2012
    Assignee: McNeil-PPC, Inc.
    Inventors: Hugh Huang, Jonathan Zeszotarski, Anthony Bean, William Michael Nichols
  • Method for stabilizing phenylephrine
    Publication number: 20090047343
    Abstract: The present invention relates to a process for stabilizing phenylephrine including drying an acidic solution of phenylephrine and pharmaceutical compositions including stabilized phenylephrine.
    Type: Application
    Filed: August 13, 2007
    Publication date: February 19, 2009
    Inventors: Hugh Huang, Jonathan Zeszotarski, Anthony Bean, William Michael Nichols
  • Denaturants for sympathomimetic amine salts
    Publication number: 20020082304
    Abstract: The instant invention makes impractical the use of sympathomimetic amine compositions in illicit drug production. More specifically, the preparation of methamphetamine from the disclosed pseudoephedrine hydrochloride formulations is inhibited. The present invention defines pharmaceutical compositions comprising a sympathomimetic amine salt and at least one combination inhibitor, the combination inhibitor which acts both to interfere with the isolation of the sympathomimetic amine from the composition and to interfere with the conversion of the sympathomimetic amine to another pharmacologically active compound. The contemplated compositions may also include reaction and separation inhibitors in any mixture to assure maximum protection against the use of the sympathomimetic amine-containing compositions for illegal drug manufacture. The presence of the combination, reaction and separation inhibitors does not significantly alter the release of the sympathomimetic amine from the composition.
    Type: Application
    Filed: November 20, 2001
    Publication date: June 27, 2002
    Inventors: William Stefan Bess, William Michael Nichols
  • Denaturants for sympathomimetic amine salts
    Patent number: 6359011
    Abstract: The instant invention makes impractical the use of sympathomimetic amine compositions in illicit drug production. More specifically, the preparation of methamphetamine from the disclosed pseudoephedrine hydrochloride formulations is inhibited. The present invention defines pharmaceutical compositions comprising a sympathomimetic amine salt and at least one combination inhibitor, the combination inhibitor which acts both to interfere with the isolation of the sympathomimetic amine from the composition and to interfere with the conversion of the sympathomimetic amine to another pharmacologically active compound. The contemplated compositions may also include reaction and separation inhibitors in any mixture to assure maximum protection against the use of the sympathomimetic amine-containing compositions for illegal drug manufacture. The presence of the combination, reaction and separation inhibitors does not significantly alter the release of the sympathomimetic amine from the composition.
    Type: Grant
    Filed: September 8, 1999
    Date of Patent: March 19, 2002
    Assignee: Warner-Lambert Company
    Inventors: William Stefan Bess, William Michael Nichols