Patents by Inventor William Michne

William Michne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Positive modulators of nicotinic acetylcholine receptors
    Publication number: 20070179172
    Abstract: Compounds of Formula I or Formula II wherein R1, X and Ar are as described in the specification, pharmaceutically-acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially for treatment of conditions associated with reductions in nicotinic transmission.
    Type: Application
    Filed: May 4, 2004
    Publication date: August 2, 2007
    Inventors: Christopher Becker, Jeanne Comstock, William Michne, Megan Murphy, Eifion Phillips, James Rosamond, Thomas Simpson
  • Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
    Patent number: 7112595
    Abstract: The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.
    Type: Grant
    Filed: November 3, 2003
    Date of Patent: September 26, 2006
    Assignees: NPS Pharmaceuticals, Inc., Astrazeneca AB
    Inventors: Bradford Van Wagenen, Thomas M. Stormann, Scott T Moe, Susan M Sheehan, Donald McLeod, Daryl L Smith, Methvin Isaac, Abdelmalik Slassi, Ian Egle, Louise Edwards, Tomislav Stefanac, Tao Xin, Jalaj Arora, William Michne
  • Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
    Publication number: 20060189661
    Abstract: The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.
    Type: Application
    Filed: April 6, 2006
    Publication date: August 24, 2006
    Inventors: Bradford Wagenen, Thomas Stormann, Scott Moe, Susan Sheehan, Donald McLeod, Daryl Smith, Methvin Isaac, Abdelmalik Slassi, Ian Egle, Louise Edwards, Tomislav Stefanac, Tao Xin, Jalaj Arora, William Michne