Abstract: Provided are a method, system, and program for forming a consistency group of data. A command is received to form a consistency group with respect to data received at a first storage site that is mirrored to a second storage site. A first data structure is provided indicating updates to the first storage site not included in the consistency group that are received after the command and a second data structure is provided indicating updates to the first storage site in the consistency group to be formed. A command is transmitted to cause data copied to the second storage site that is part of the consistency group to be copied to a third storage site. Indication is received when the data in the second storage site that is part of the consistency group is copied to the third storage site.

Abstract: Provided are a method, system, and program for forming a consistency group of data. Information is provided on a consistency group relationship indicating a plurality of slave controllers and, for each indicated slave controller, a slave storage unit managed by the slave controller. A command is transmitted to each slave controller in the consistency group relationship to cause each slave controller to transmit data in the slave storage unit to a remote storage in a manner that forms the consistency group. A determination is made as to whether all the slave controllers successfully transmitted the data in the slave storage units that is part of the consistency group to the remote storage.

Abstract: Disclosed is a technique for maintaining consistency of data. One or more blocks of data identified by a first structure are copied to form a consistent set of data. While not acknowledging completion of write requests to any blocks of data, a second structure is created, wherein the second structure indicates which blocks of data are modified while the consistent set of data is being formed. Also disclosed is a technique for asynchronous copy. Indicators are updated in a first structure for one or more blocks of data, wherein each indicator in the first structure indicates whether a corresponding block of data was modified since the block of data was last sent to remote storage.

Abstract: Inhibitors of type 2 methionine aminopeptidases (“MetAP2”), specifically dominant negative variants of MetAP2, both polypeptides and encoding polynucleotides, are provided. Also provided are methods of treating subjects suffering from cancer, diseases mediated by the immune system or opportunistic infections using inhibitors of MetAP2. Also provided are high through put screens and assays to detect and identify inhibitors of MetAP2 and downstream effectors of MetAP2.

Abstract: A method to copy information to two data storage devices. The method provides a first data storage device and a second data storage device, where the first data storage device is capable of communicating with the second data storage device. The method provides first information and a write command to the first data storage device at a first time. The method determines if the write command comprises a synchronous copy attribute. If the write command comprises a synchronous copy attribute, then the method synchronously provides the first information to the second data storage device. Alternatively, if the write command does not comprise a synchronous copy attribute, then the method provides the first information to the second data storage device at a second time, where that second time is later than the first time.

Abstract: Disclosed are a system, a method, and a computer program product to efficiently create consistent transaction sets to maintain one or more copies of data at different data storage sites. All transactions sent to a primary backup appliance during a consistent transaction set creation interval are formed into a consistent transaction set by efficiently adding new transactions as they are received and removing unnecessary transfers as newer versions arrive. When the creation interval has expired, the complete consistent transaction set is transferred to a secondary backup appliance to be used to update a consistent backup copy of the primary site data. For each consistent transaction set, there will be a tree data structure (a search tree) created that contains the addressing information for all of the blocks of data in the consistent transaction set.