Abstract: The present invention provides methods and compositions for modulating transendothelial migration (TEM) of leukocytes. In particular, inhibition of TEM can provide a potent therapeutic approach to treating inflammatory conditions. The invention specifically relates to the discovery that CD99 mediates TEM, because blocking CD99 on either endothelial cells or monocytes bloks migration 80-90%. In conjunction with PECAM inhibitors, TEM blockade approaches 100%. CD99 is involved in a step in TEM that is distal to the step controlled by PECAM.

Abstract: The invention concerns equipment for extracting root post prosthetic elements or implants, such as an instrument including two lever assembled together by a pivoting and non-intersecting articulation, each of the levers having a handle and an extracting branch extending on either side of the articulation such that when the two handles are brought closer together, the two extracting branches are spaced apart. The ends of the extracting branches of the instruments are curved so as to form an angle with the remaining part of the branches. There are U-shaped extracting end pieces designed to be removably positioned and pivotably mounted, at the curved ends of the extracting branches.

Abstract: An instrument for removing a crown by generating a couple of forces between the occlusal surface of the stump of the tooth and the basal surface of the crown. The instrument has an indented intermediate portion and a working part extending from a tapered intermediate portion and a handle. When inserted in a groove formed at the occlusal part of the stump along a plane substantially parallel to the occlusal surface of the crown, the working portion enables, by a physical action, exertion of a couple of forces between the respective occlusal surfaces of the stump and the basal surface of the crown. The working part is rotatable integrally and correspondingly with a rotation of the handle.

Abstract: An instrument for setting a crown or a sealed prosthesis on a natural or prosthetic support by generating a couple of forces between the occlusal surface of the stump and the basal surface of the crown. The instrument includes an indented intermediate portion and a working portion, which may include an extension of a handle and a tapered intermediate portion. When inserted in a groove previously performed by the practitioner at a supposed level of the occlusal part of the stump along a plane substantially parallel to the occlusal surface of the crown, the working portion enables, by a physical action, exertion of a couple of forces between the respective occlusal surfaces of the stump and the basal surface of the crown. The couple of forces being generated subtantially in the vertical axis of the tooth or implant, the instrument enables to limit the traumas for the patient, to preserve the support base, to safeguard the prosthesis for future resetting.