Abstract: The invention provides for methods and systems for engineering target proteins, based on protein sequence characteristics that influence the likelihood of obtaining a crystal suitable for X-ray structure solution, to improve protein crystallization, as well as related material.

Abstract: The invention provides for methods and systems for engineering target proteins, based on protein sequence characteristics that influence the likelihood of obtaining a crystal suitable for X-ray structure solution, to improve protein crystallization, as well as related material.

Abstract: This patent document discloses assemblies, alignment devices and methods for creating a bi-directional path through an occlusion. An alignment device can include a positioning member and a tubular member. The tubular member can be coupled with a distal end portion of the positioning member and can include proximal and distal progressive size-changing shapes separated by a narrow neck passageway. An assembly can include the alignment device, a guide catheter having a lumen in which the alignment device is at least partially positioned, a guidewire, and a specialty catheter for supporting the guidewire. The alignment device and the guide catheter can be advanced in an antegrade direction to a proximal end of the occlusion, and the guidewire and the specialty catheter can be advanced in a retrograde direction to a distal end of the occlusion. The guidewire and the specialty catheter can be manipulated through the occlusion and into the distal end of the tubular member.

Abstract: The invention is directed to methods and metric suitable for use in determining the solubility, expression and usability of a polypeptide encoded by a nucleic acid sequence. In certain aspects, the invention also relates to methods for introducing modifications in a polypeptide, for example through substitution of one or more codons in the nucleic acid sequence encoding the polypeptide, to increase or decrease the solubility, expression or usability of the polypeptide.

Abstract: Compositions and devices for the production of treated wood products are disclosed. A moisture exchange container for treating a plurality of wood pieces with a chemical formulation of interest is described. Also, an adhesive suitable for gluing wood pieces that have been treated, or that are going to be treated, with a chemical formulation of interest is described. Also disclosed are methods and systems using the devices and compositions of the present invention, and treated wood products.

Abstract: The invention provides for methods and systems for engineering target proteins, based on protein sequence characteristics that influence the likelihood of obtaining a crystal suitable for X-ray structure solution, to improve protein crystallization, as well as related material.

Abstract: Compositions and devices for the production of treated wood products are disclosed. A moisture exchange container for treating a plurality of wood pieces with a chemical formulation of interest is described. Also, an adhesive suitable for gluing wood pieces that have been treated, or that are going to be treated, with a chemical formulation of interest is described. Also disclosed are methods and systems using the devices and compositions of the present invention, and treated wood products.

Abstract: Compositions and devices for the production of treated wood products are disclosed. A moisture exchange container for treating a plurality of wood pieces with a chemical formulation of interest is described. Also, an adhesive suitable for gluing wood pieces that have been treated, or that are going to be treated, with a chemical formulation of interest is described. Also disclosed are methods and systems using the devices and compositions of the present invention, and treated wood products.

Abstract: An impact sensing and tracking system helps detect concussion risks using a computerized evaluation combined with traditional methods. The system includes impact sensors, a application and a centralized database with a webpage browser interface. Impact sensors are worn on athletes' heads, helmet or other headwear and measure impacts that athletes receive while playing sports. The mobile application includes a real-time test and alert system which assists play-side help detect concussion symptoms, provides medical care notices and reports test results to the database for tracking and analysis. The impact data for each athlete is stored in the database along with tests that have been administered through the application. The system reviews, analyzes and compares impact data to standardized concussion data and stores it as a comprehensive, long-term diagnostic study on diagnosed concussions in athletes that the system uses to evaluate impact severities and concussion risks in specific situations.

Abstract: A door system can have a door that can both slide and pivot open. The door can be positioned in a door frame. The door can slide within the door frame using tracks, rollers, and/or guides. The door can be prevented from swinging open while the door is sliding along the doorframe. The door can swing open along a pivot point when a side of the door substantially abuts a side of the doorframe. The door can be prevented from sliding while door is swung open.

Abstract: A door system can have a door that can both slide and pivot open. The door can be positioned in a door frame. The door can slide within the door frame using tracks, rollers, and/or guides. The door can be prevented from swinging open while the door is sliding along the doorframe. The door can swing open along a pivot point when a side of the door substantially abuts a side of the doorframe. The door can be prevented from sliding while door is swung open.

Abstract: Compositions and devices for the production of treated wood products are disclosed. A moisture exchange container for treating a plurality of wood pieces with a chemical formulation of interest is described. Also, an adhesive suitable for gluing wood pieces that have been treated, or that are going to be treated, with a chemical formulation of interest is described. Also disclosed are methods and systems using the devices and compositions of the present invention, and treated wood products.

Abstract: System and method for reserving and booking vacation rental properties. The method may include receiving first user input from a first user to a website requesting reservation of a vacation rental property. The first user input may include contact information. The method may further include providing the first user input to a second user regarding the requested reservation of the vacation rental property. The contact information may be usable to contact the first user. The method may include receiving second user input specifying a reservation of the vacation rental property. The reservation may include reservation dates and a reservation price. The reservation may be provided to the first user, and payment information may be received for the reservation.

Abstract: A wireless interface for a diagnostic instrument is provided. The diagnostic instrument includes a communications interface having an external data port. A wireless adapter coupled to the external data port communicates diagnostic data with one or more computing devices. In a single user mode, a computing device can control several diagnostic instruments wirelessly. In broadcast mode, a diagnostic instrument can send a data stream wirelessly to many listening computing devices. Further features, such as safety warning messages, are provided.

Abstract: An applicator tip for an applicator for applying a polymerizable monomeric adhesive composition can include a bioactive material, a flavorant, a polymerization initiator, and/or a polymerization rate modifier.

Abstract: A method for chemical analysis of fluids utilized in hydrocarbon exploration and production in which microfluidic systems designed to react to specific characteristics of a fluid are introduced into fluid samples or during operations. The microfluidic systems are then recovered and subjected to analysis to permit one to measure the desired characteristics.

Abstract: A wireless interface for a diagnostic instrument is provided. The diagnostic instrument includes a communications interface having an external data port. A wireless adapter coupled to the external data port communicates diagnostic data with one or more computing devices. In a single user mode, a computing device can control several diagnostic instruments wirelessly. In broadcast mode, a diagnostic instrument can send a data stream wirelessly to many listening computing devices. Further features, such as safety warning messages, are provided.

Abstract: A multipurpose multifunctional (M/M) interface device system comprises one or more system ports configured to couple to a system to be diagnosed; one or more diagnostic ports configured to couple to at least one diagnostic system; a set of power management modules configured to provide a full power level and a reduced power level; and a main processor module configured to control communications between the system ports and the diagnostic ports. The main processor module selectively transitions the M/M interface device between a standby mode at the reduced power level and an operational mode at the full power level in response to prescribed criteria. The device is useful in vehicle diagnostics, such as gas analyses, and other applications.

Abstract: A user interface for a computing device is provided. The user interface includes a plurality of display elements. A display element includes an active region, a graphical representation, and a textual description. The active region is sized for enabling human finger tip selection of the display element on a touch sensitive display screen. A display module receives coordinate information from the display screen and determines whether the coordinate information corresponds to the active region. When a user touches the active region, an instrument interface module sends a command to a diagnostic instrument. Further features, such as language localization of the textual description, are also provided.

Abstract: A semi-automated apparatus and process for combining virgin blend material and reground tablet material, said apparatus comprising: (a) a chamber including an inlet for said virgin blend material; (b) a hopper including an inlet for said reground tablet material; and (c) a feeder for feeding said reground tablet material from said hopper to said chamber for combining with said virgin blend material, wherein said feeder controls the rate of feeding to said chamber.