Patents by Inventor William Nicholson Price, II

William Nicholson Price, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineering surface epitopes to improve protein crystallization
    Publication number: 20190214107
    Abstract: The invention provides for methods and systems for engineering target proteins, based on protein sequence characteristics that influence the likelihood of obtaining a crystal suitable for X-ray structure solution, to improve protein crystallization, as well as related material.
    Type: Application
    Filed: January 18, 2019
    Publication date: July 11, 2019
    Inventors: Victor NAUMOV, William Nicholson PRICE, II, Samuel K. HANDELMAN, John Francis HUNT, III
  • METHODS FOR ALTERING POLYPEPTIDE EXPRESSION AND SOLUBILITY
    Publication number: 20160186188
    Abstract: The invention is directed to methods and metric suitable for use in determining the solubility, expression and usability of a polypeptide encoded by a nucleic acid sequence. In certain aspects, the invention also relates to methods for introducing modifications in a polypeptide, for example through substitution of one or more codons in the nucleic acid sequence encoding the polypeptide, to increase or decrease the solubility, expression or usability of the polypeptide.
    Type: Application
    Filed: February 9, 2011
    Publication date: June 30, 2016
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: John F. Hunt, III, William Nicholson Price, II, Gaetano T. Montelione, Gregory P. Boel, Thomas Acton, Helen Neely
  • ENGINEERING SURFACE EPITOPES TO IMPROVE PROTEIN CRYSTALLIZATION
    Publication number: 20150269308
    Abstract: The invention provides for methods and systems for engineering target proteins, based on protein sequence characteristics that influence the likelihood of obtaining a crystal suitable for X-ray structure solution, to improve protein crystallization, as well as related material.
    Type: Application
    Filed: October 18, 2013
    Publication date: September 24, 2015
    Inventors: Victor Naumov, William Nicholson Price, II, Samuel K. Handelman, John Francis Hunt, III