Abstract: Active compression devices, methods of assembly and methods of use are disclosed. A bone fixation device may include a first member, a second member shaped to engage the first member, and at least one deformable member. A bone fusion device including a female member with a proximal and distal end, a male member with a proximal and distal end, and at least one elastic element positioned between the female member and the male member. A bone plating device including a first member, a second member shaped to engage the first member, and at least one deformable member positioned between the first member and the second member. Methods of assembling and using the bone fixation devices, bone fusion devices, and bone plating devices are also disclosed.

Abstract: Active compression devices, methods of assembly and methods of use are disclosed. A bone fixation device may include a first member, a second member shaped to engage the first member, and at least one deformable member. A bone fusion device including a female member with a proximal and distal end, a male member with a proximal and distal end, and at least one elastic element positioned between the female member and the male member. A bone plating device including a first member, a second member shaped to engage the first member, and at least one deformable member positioned between the first member and the second member. Methods of assembling and using the bone fixation devices, bone fusion devices, and bone plating devices are also disclosed.

Abstract: Active compression devices, methods of assembly and methods of use are disclosed. A bone fixation device may include a first member, a second member shaped to engage the first member, and at least one deformable member. A bone fusion device including a female member with a proximal and distal end, a male member with a proximal and distal end, and at least one elastic element positioned between the female member and the male member. A bone plating device including a first member, a second member shaped to engage the first member, and at least one deformable member positioned between the first member and the second member. Methods of assembling and using the bone fixation devices, bone fusion devices, and bone plating devices are also disclosed.

Abstract: Active compression devices, methods of assembly and methods of use are disclosed. A bone fixation device may include a first member, a second member shaped to engage the first member, and at least one deformable member. A bone fusion device including a female member with a proximal and distal end, a male member with a proximal and distal end, and at least one elastic element positioned between the female member and the male member. A bone plating device including a first member, a second member shaped to engage the first member, and at least one deformable member positioned between the first member and the second member. Methods of assembling and using the bone fixation devices, bone fusion devices, and bone plating devices are also disclosed.

Abstract: Active compression devices, methods of assembly and methods of use are disclosed. A bone fixation device may include a first member, a second member shaped to engage the first member, and at least one deformable member. A bone fusion device including a female member with a proximal and distal end, a male member with a proximal and distal end, and at least one elastic element positioned between the female member and the male member. A bone plating device including a first member, a second member shaped to engage the first member, and at least one deformable member positioned between the first member and the second member. Methods of assembling and using the bone fixation devices, bone fusion devices, and bone plating devices are also disclosed.

Abstract: Disclosed is a gas permeable electrode comprising an electrocatalyst which is permeable to a reactant or reaction product, the electrocatalyst comprising particulate boron-doped diamond. There is also disclosed a method of making an electrocatalyst which is permeable to a reactant or reaction product, the method comprising the step of forming an electrocatalyst comprising particulate boron-doped diamond.

Abstract: A method of creating a fuse. The method comprises the steps of creating a fusible link electrically connecting a first terminal portion to a second terminal portion, the fusible link, the first terminal portion and the second terminal portion being made of a first electrically conductive material; and spraying a coating of a second electrically conductive material onto the fusible link. The second electrically conductive material has a lower melting point than the first electrically conductive material and is absorbable in the first electrically conductive material.

Abstract: An endplate for an intervertebral prosthesis prosthesis endplate of the invention includes: a generally planar base plate, a first elevated region, or dome, within the base plate periphery, and a second elevated region, or dome, within the boundary of the first elevated region. The antero-posterior and side-to-side (medial-lateral) dimensions of the first elevated region are made to be unequal in order to provide resistance to torsional stresses, and the laterally opposite sidewalls of the first elevated region are defined by arcs that terminate in sagittal planes of the endplate, and are symmetrical with respect to a coronal plane of the endplate. A bone rasp for preparing a surgical site for implantation of the prosthesis has a rasp head having a pivot point and rasp teeth arranged to produce a recess or seat of predetermined shape.

Abstract: A method of manufacturing a patterned electric circuit. The method comprises the steps of providing a cold gas-dynamic spraying (CGDS) device, providing a substrate, and depositing a pattern of electrically conductive material with the CGDS device on the substrate by relative movement between the CGDS device to the substrate.

Abstract: Compounds represented by formula 1: wherein R1 is H, halogen, (C1-4)alkyl, O(C1-4)alkyl, and haloalkyl; R2 is H or methyl; R3 is H or (C1-4)alkyl; R4 is H or (C1-4)alkyl; R5 is (C1-4)alkyl, (C1-4)alkyl(C3-7)cyclo-alkyl or (C3-7)cycloalkyl; and W is a fused phenyl-5 or 6-membered heterocycle having one or two heteroatoms selected from N or S; or W is phenyl, 1,1?-biphenyl, 2,3-dihydro-1H-indene, 1,2,3,4-tetrahydronaphthyl, or naphthyl; said W being optionally substituted with (C1-4)alkyl, which in turn can be optionally substituted with a carboxy or (C1-4)alkoxycarbonyl, or a salt or ester thereof. The compounds have inhibitory activity against Wild Type, single and double mutant strains of HIV.

Abstract: An interpositional biarticular disk implant (11) having a circular peripheral rim, a generally toroidal axial center opening (13) and convex upper and lower surfaces (15, 17) is implanted between resected concave surfaces of the metacarpal base and the trapezium or other carpal bone in a CMC joint replacement. The disk (11) is anchored in operative position through the use of a flexable cond, such as a harvested tendon that passes through the center opening (13) and through osseous passageways created in the two facing bones.

Abstract: A compound of formula (I) or its enantiomers or diastereoisomers thereof: wherein: A, X, W, R1, Y; R3; and R4 are as defined herein. The compounds of the invention may be used as inhibitors of the papilloma virus E1-E2-DNA complex. The invention further provides a method of treating or preventing human papilloma virus infection.

Abstract: Compounds represented by formula I: wherein R1 is H, halogen, (C1-4)alkyl, O(C1-4)alkyl, and haloalkyl; R2 is H or (C1-4)alkyl; R3 is H or (C1-4)alkyl; R4 is (C1-4)alkyl, (C1-4)alkyl(C3-7)cycloalkyl, or (C3-7)cycloalkyl; and Q is a fused phenyl-5 or 6-membered saturated heterocycle having one to two heteroatoms selected from O and N, said Q being optionally substituted with hydroxy, or (C1-4)alkyl which in turn maybe optionally substituted with pyridinyl-N-oxide or C(O)OR wherein R is H or (C1-4)alkyl; or a salt thereof. The compounds have inhibitory activity against Wild Type, and single and double mutants strains, of HIV.

Abstract: Hemi joint replacements for the base of the first metacarpal of the CMC joint are provided which can effectively restore and reestablish functional joint mechanics while preserving the soft tissues that contribute to joint stability and function. The implants have a unique head shape with a saddle-like articular surface that is shaped somewhat similar to a conventional bicycle seat. A set of four proportionately larger and smaller implants allows a surgeon to choose the appropriately sized prosthesis for implantation in respect of the metacarpal osteotomy.

Abstract: A compound of formula (I) or its enantiomers or diastereoisomers thereof: wherein: A,; X, W, R1, Y; R3; and R4 are as defined herein. The compounds of the invention may be used as inhibitors of the papilloma virus E1-E2-DNA complex. The invention further provides a method of treating or preventing human papilloma virus infection.

Abstract: Compounds represented by formula 1: 1

Abstract: Compounds represented by formula I: 1

Abstract: A window for a waveguide for a beam of electromagnetic radiation. The window includes a layer of a material capable of allowing electromagnetic radiation to pass therethrough and a support on each side of the layer. Each support defines a passage for electromagnetic radiation. Further, the layer is provided with at least one recess formed in the periphery thereof.

Abstract: A compound of formula (I) is disclosed: wherein X, z, W, Y, R1 through R5, m and n are as define herein. These compounds are peptidomimetic inhibitors of human cytomegalovirus (HCMV) protease and are useful for the treatment of human cytomegalovirus infection.