Patents by Inventor William P. Van Antwerp

William P. Van Antwerp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10073948
    Abstract: Systems and processes for managing data relating to one or more medical or biological conditions of a plurality of subjects (such as patients) over a wide area network, such as the Internet, may be employed for diabetes subjects or subjects with other medical conditions requiring monitoring and/or treatment over time. Such systems and processes provide various functions for several types of users, including patients or subject-users, healthcare provider-users and payor entity-users and combinations thereof, which allow for improved treatment and medical data management of individual subjects and groups of subjects and which allow collection and analysis of aggregate data from many subject sources, for improving overall healthcare practices of providers and subjects (e.g., patients).
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 11, 2018
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Gary Cohen, Joel Goldsmith, Pam S. Roller, Sanford Widran, George W. Patterson, James R. Daugherty, William P. Van Antwerp
  • Publication number: 20160324930
    Abstract: Medical systems and methods for treating kidney disease alone, heart failure alone, kidney disease with concomitant heart failure, or cardiorenal syndrome are described. The systems and methods are based on delivery of a chimeric natriuretic peptide to a patient. Methods for increasing peptide levels include direct peptide delivery via either an external or implantable programmable pump.
    Type: Application
    Filed: March 14, 2016
    Publication date: November 10, 2016
    Inventors: William P. Van Antwerp, VenKatesh R. Manda, Andrew J. L. Walsh, John Burns, Daron Evans, Hsiao Lieu
  • Publication number: 20160317622
    Abstract: Methods of treating heart failure, or decreasing blood pressure, comprising administering an NP at an appropriate does, or in an amount sufficient to provide particular concentrations of NP, are provided.
    Type: Application
    Filed: March 10, 2016
    Publication date: November 3, 2016
    Inventors: Daron Evans, Hsiao Lieu, William P. Van Antwerp
  • Patent number: 9314507
    Abstract: Methods of treating heart failure, or decreasing blood pressure, comprising administering an NP at an appropriate dose, or in an amount sufficient to provide particular concentrations of NP, are provided.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: April 19, 2016
    Assignee: Capricor Therapeutics, INC.
    Inventors: Daron Evans, Hsiao Lieu, William P. Van Antwerp
  • Patent number: 9237865
    Abstract: Embodiments of the invention provide analyte sensors having elements designed to modulate their chemical reactions as well as methods for making and using such sensors. In certain embodiments of the invention, the sensor includes a hydrophilic comb-copolymer having a central chain and a plurality of side chains coupled to the central chain, wherein at least one side chain comprises a silicone moiety.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: January 19, 2016
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Yunbing Wang, Rajiv Shah, Jenn-Hann Larry Wang, William P. Van Antwerp, Brooks B. Cochran
  • Patent number: 8948836
    Abstract: An apparatus for sensing multiple parameters includes an implantable housing and a plurality of implantable sensors disposed within the implantable housing. The plurality of implantable sensors sense parameters in a patient, such as biological or physiological parameters, for example, and each responds to an analyte in the patient. The plurality of implantable sensors may include, but is not limited to, electrochemical, potentiometric, current and optical sensors.
    Type: Grant
    Filed: December 26, 2003
    Date of Patent: February 3, 2015
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Bahar Reghabi, Rebecca K. Gottlieb, Rajiv Shah, Bradley J. Enegren, William P. Van Antwerp
  • Publication number: 20140200923
    Abstract: Systems and processes for managing data relating to one or more medical or biological conditions of a plurality of subjects (such as patients) over a wide area network, such as the Internet, may be employed for diabetes subjects or subjects with other medical conditions requiring monitoring and/or treatment over time. Such systems and processes provide various functions for several types of users, including patients or subject-users, healthcare provider-users and payor entity-users and combinations thereof, which allow for improved treatment and medical data management of individual subjects and groups of subjects and which allow collection and analysis of aggregate data from many subject sources, for improving overall healthcare practices of providers and subjects (e.g., patients).
    Type: Application
    Filed: March 14, 2014
    Publication date: July 17, 2014
    Applicant: Medtronic MiniMed, Inc.
    Inventors: Gary COHEN, Joel GOLDSMITH, Pam S. ROLLER, Sanford WIDRAN, George W. PATTERSON, James R. DAUGHERTY, William P. VAN ANTWERP
  • Patent number: 8715180
    Abstract: Systems and processes for managing data relating to one or more medical or biological conditions of a plurality of subjects (such as patients) over a wide area network, such as the Internet, may be employed for diabetes subjects or subjects with other medical conditions requiring monitoring and/or treatment over time. Such systems and processes provide various functions for several types of users, including patients or subject-users, healthcare provider-users and payor entity-users and combinations thereof, which allow for improved treatment and medical data management of individual subjects and groups of subjects and which allow collection and analysis of aggregate data from many subject sources, for improving overall healthcare practices of providers and subjects (e.g., patients).
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: May 6, 2014
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Gary Cohen, Joel Goldsmith, Pam S. Roller, Sanford Widran, George W. Patterson, James R. Daugherty, William P. Van Antwerp
  • Patent number: 8523773
    Abstract: A long term analyte sensor for measuring at least one analyte in the body of a user and which includes a housing, a plurality of analyte contacting sensor elements and at least one structure for relaying information away from the sensor. This plurality of analyte contacting sensor elements are typically disposed in an array. The analyte sensor further includes at least one sensor protection membrane that is controllable in a manner such that sensor elements may be activated (e.g. exposed to the external environment) at different times so as to extend the useful life of the sensor. In illustrative analyte sensors, the analyte is glucose.
    Type: Grant
    Filed: July 15, 2009
    Date of Patent: September 3, 2013
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Rajiv Shah, Rebecca K. Gottlieb, Eric A. Grovender, Shaun M. Pendo, Paul Citron, William P. Van Antwerp
  • Patent number: 8454566
    Abstract: Embodiments of the invention provide compositions which are effective to inhibit the development of biofilms on a surface of a medical device having the composition applied thereto, to medical devices having the composition applied to a surface thereof and to methods for using the compositions to coat medical devices.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: June 4, 2013
    Assignee: Medtronic MiniMed, Inc.
    Inventor: William P. Van Antwerp
  • Patent number: 8313433
    Abstract: Systems and processes for managing data relating to one or more medical or biological conditions of a plurality of subjects (such as patients) over a wide area network, such as the Internet, may be employed for diabetes subjects or subjects with other medical conditions requiring monitoring and/or treatment over time. Such systems and processes provide various functions for several types of users, including patients or subject-users, healthcare provider-users and payor entity-users and combinations thereof, which allow for improved treatment and medical data management of individual subjects and groups of subjects and which allow collection and analysis of aggregate data from many subject sources, for improving overall healthcare practices of providers and subjects (e.g., patients).
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: November 20, 2012
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Gary Cohen, Joel Goldsmith, Pam S. Roller, Sanford Widran, George W. Patterson, James R. Daugherty, William P. Van Antwerp
  • Publication number: 20120220528
    Abstract: Medical systems and methods for treating kidney disease alone, heart failure alone, kidney disease with concomitant heart failure, or cardiorenal syndrome are described. The systems and methods are based on delivery of a chimeric natriuretic peptide to a patient. Methods for increasing peptide levels include direct peptide delivery via either an external or implantable programmable pump.
    Type: Application
    Filed: February 7, 2012
    Publication date: August 30, 2012
    Applicant: MEDTRONIC, INC.
    Inventors: William P. Van Antwerp, VenKatesh R. Manda, Andrew J. L. Walsh, John Burnes, Daron Evans, Hsiao Lieu
  • Publication number: 20120216297
    Abstract: Systems and processes for managing data relating to one or more medical or biological conditions of a plurality of subjects (such as patients) over a wide area network, such as the Internet, may be employed for diabetes subjects or subjects with other medical conditions requiring monitoring and/or treatment over time. Such systems and processes provide various functions for several types of users, including patients or subject-users, healthcare provider-users and payor entity-users and combinations thereof, which allow for improved treatment and medical data management of individual subjects and groups of subjects and which allow collection and analysis of aggregate data from many subject sources, for improving overall healthcare practices of providers and subjects (e.g., patients).
    Type: Application
    Filed: April 26, 2012
    Publication date: August 23, 2012
    Inventors: Gary Cohen, Joel Goldsmith, Pam S. Roller, Sanford Widran, George W. Patterson, James R. Daugherty, William P. Van Antwerp
  • Publication number: 20110270212
    Abstract: Methods and devices for treating patients having chronic hepatitis C infection so as to eradicate detectable HCV-RNA and/or inhibit the emergence of a drug resistant HCV variant are disclosed. Certain methods of the invention involve the use of a continuous infusion pump in a multiphasic combination therapy using a therapeutically effective amount of a small molecule inhibitor such as ribavirin and a therapeutically effective amount of interferon-?.
    Type: Application
    Filed: October 3, 2008
    Publication date: November 3, 2011
    Applicant: MEDTRONIC, INC.
    Inventors: William P. Van Antwerp, Thomas J. Vasicek
  • Patent number: 8034764
    Abstract: A method is provided for treating conditions that are susceptible of treatment with a cytokine wherein certain physiological processes normally associated with cytokine administration (e.g. the induction of SOCS 1 and/or SOCS 3) are diminished or eliminated. The method comprises continuously administering a controlled dose of a cytokine to an individual afflicted with a condition susceptible of treatment with the cytokine.
    Type: Grant
    Filed: September 8, 2004
    Date of Patent: October 11, 2011
    Assignee: Medtronic MiniMed, Inc.
    Inventors: William P. Van Antwerp, Poonam S. Gulati
  • Publication number: 20110184389
    Abstract: Apparatuses and methods for pumping fluids such as fluid medications are disclosed. Embodiments of the invention provide an osmotic pump fluid delivery apparatus including elements designed to control the fluid delivery rate. Typical embodiments of the invention include an arrangement of elements such as solute reservoirs that can manipulate the solute concentrations within an inner osmotic compartment or compartments of an osmotic pump so as to control fluid delivery from the pump. Other embodiments include sealed electro-osmotic pumps that do not discharge ions into the surroundings or require water from an external source. These embodiments of the invention provide new ways to control fluid delivery in apparatuses that employ osmotic processes to function.
    Type: Application
    Filed: March 31, 2011
    Publication date: July 28, 2011
    Applicant: MEDTRONIC, INC.
    Inventors: Eric A. Grovender, Ashok V. Joshi, John Howard Gordon, Sai Bhavaraju, William P. Van Antwerp
  • Publication number: 20110184379
    Abstract: Methods for treating Hepatitis infections are provided. In one embodiment, an initial dosage of interferon is administered to a patient, and interferon serum levels and viral load data is collected over time. This data can be used to determine patient-specific pharmacokinetic and pharmacodynamic parameters and then construct patient-specific interferon delivery profiles. Patient-specific delivery profiles can then be used to design patient-specific therapeutic regimens.
    Type: Application
    Filed: March 27, 2009
    Publication date: July 28, 2011
    Applicant: MEDTRONIC, INC.
    Inventors: William P. Van Antwerp, Robert C. Hamlen, Eric A. Grovender
  • Publication number: 20110027229
    Abstract: Methods and systems for treating Hepatitis C infections are provided. Typically the method comprises administering interferon-? to the patient subcutaneously using a continuous infusion apparatus, wherein this therapeutic regimen is sufficient to maintain circulating levels of interferon-? in the serum of the patient above a target concentration for a certain period of time.
    Type: Application
    Filed: August 2, 2010
    Publication date: February 3, 2011
    Applicant: MEDTRONIC, INC.
    Inventors: William P. Van Antwerp, Eric A. Grovender, Harry L. A. Janssen, Robert J. De Knegt
  • Patent number: 7875008
    Abstract: A catheter for use in delivery or withdrawal of a formulation, wherein the catheter has an outer layer comprising a bio-compatible material and a barrier layer comprising a material that provides a more effective barrier than the outer layer against inward and outward diffusion of substances that may cause destabilization of the formulation. The catheter may include a flared distal end tip to aid in the release, during a bolus delivery or catheter flush, of any obstruction situated at the distal end tip of the catheter. The catheter may also include a slit valve at the distal end tip which has one or more and, preferably a plurality of slits that may be elastically extended to an open position by the expulsion of the formulation during an IIP pump stroke. During the interval between IIP pump strokes, the slits return to a closed position and hinder the inflow of body fluid into the distal end tip.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: January 25, 2011
    Assignee: Medtronic Minimed, Inc.
    Inventors: Colin Chong, Keith Oberg, Paul Mounce, Peter C. Lord, William P. Van Antwerp
  • Publication number: 20100331647
    Abstract: A long term analyte sensor for measuring at least one analyte in the body of a user and which includes a housing, a plurality of analyte contacting sensor elements and at least one structure for relaying information away from the sensor. This plurality of analyte contacting sensor elements are typically disposed in an array. The analyte sensor further includes at least one sensor protection membrane that is controllable in a manner such that sensor elements may be activated (e.g. exposed to the external environment) at different times so as to extend the useful life of the sensor. In illustrative analyte sensors, the analyte is glucose.
    Type: Application
    Filed: July 15, 2009
    Publication date: December 30, 2010
    Applicant: MEDTRONIC MINIMED, INC.
    Inventors: Rajiv Shah, Rebecca K. Gottlieb, Eric A. Grovender, Shaun M. Pendo, Paul Citron, William P. Van Antwerp