Abstract: Many epidemics such as the opioid epidemic, are complex and dynamic, yet relatively little is known regarding its likely future impact and the potential mitigating impact of interventions to address it. The instant systems and methods provide a dynamic decision dynamic open Markov model, configured to provide updated estimates of the future magnitude of an epidemic, and project the potential association of key interventions with mitigation of the epidemic via a redress model and abatement model. This novel approach addresses the deficiencies of conventional approaches to modeling opioid epidemics by granularly analyzing populations via a framework including an open Markov model, redress model, abatement model, and evaluation model, that simulate the impact of interventions on the population, and forecast the remedies and resources required to abate the epidemic.

Abstract: Methods for identifying indications for testing for Lyme related infection are described. A subject, presenting a sudden onset of at least one visual symptom known to be associated with Lyme related infection, may be screened for peri-papillary ischemia and, if peri-papillary ischemia is present, the subject may be recommended to undergo further testing for Lyme related infection.

Abstract: A method and apparatus of providing wave-front color therapy using a computer or portable handheld devices such as PDA's and other portable telecommunication devices to deliver a specific different nanometer wavelength of light to affect a wide variety of visual, binocular, function, perceptual, and cognitive-related vision imbalances that interfere with function and performance. The current proposed device would provide specific treatment for these difficulties by delivering different wavelengths of light through a computer monitor. The exact therapeutic prescription including nanometer specifications and hue-saturation will be prescribed for individuals with a wide range of visual problems caused by a traumatic brain injury, cerebrovascular accident, and Multiple Sclerosis, and the like, to name a few examples. This disclosure claims analog and digital relations of light as it relates to both the spatial and temporal relationship of light.