Patents by Inventor William Paul Duprex

William Paul Duprex has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MEASLES VIRUS VACCINE EXPRESSING SARS-COV-2 PROTEIN(S)
    Publication number: 20230272421
    Abstract: A recombinant measles viral vector comprising a nucleic acid sequence encoding a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spike glycoprotein is provided. Polypeptides comprising the SARS-CoV-2 spike glycoprotein also are provided, as well as related nucleic acids, vectors, and compositions. The polypeptides, nucleic acids, vectors, and compositions can be used in methods of preventing, inhibiting, reducing, eliminating, protecting, or delaying the onset of an infection or an infectious clinical condition caused by coronavirus and methods for inducing an immune response against a coronavirus.
    Type: Application
    Filed: June 15, 2021
    Publication date: August 31, 2023
    Inventors: William Paul DUPREX, Natasha TILSTON-LUNEL, Shamkumar NAMBULLI, Linda J. MURPHY
  • Measles virus vaccine expressing SARS-CoV-2 protein(s)
    Patent number: 11298417
    Abstract: A recombinant measles viral vector comprising a nucleic acid sequence encoding a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spike glycoprotein is provided. Polypeptides comprising the SARS-CoV-2 spike glycoprotein also are provided, as well as related nucleic acids, vectors, and compositions. The polypeptides, nucleic acids, vectors, and compositions can be used in methods of preventing, inhibiting, reducing, eliminating, protecting, or delaying the onset of an infection or an infectious clinical condition caused by coronavirus and methods for inducing an immune response against a coronavirus.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: April 12, 2022
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: William Paul Duprex, Natasha Louise Tilston-Lunel, Shamkumar Nambulli
  • MEASLES VIRUS VACCINE EXPRESSING SARS-COV-2 PROTEIN(S)
    Publication number: 20210386852
    Abstract: A recombinant measles viral vector comprising a nucleic acid sequence encoding a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spike glycoprotein is provided. Polypeptides comprising the SARS-CoV-2 spike glycoprotein also are provided, as well as related nucleic acids, vectors, and compositions. The polypeptides, nucleic acids, vectors, and compositions can be used in methods of preventing, inhibiting, reducing, eliminating, protecting, or delaying the onset of an infection or an infectious clinical condition caused by coronavirus and methods for inducing an immune response against a coronavirus.
    Type: Application
    Filed: January 7, 2021
    Publication date: December 16, 2021
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventor: William Paul Duprex
  • Measles virus vaccine expressing SARS-COV-2 protein(s)
    Patent number: 11103576
    Abstract: A recombinant measles viral vector comprising a nucleic acid sequence encoding a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spike glycoprotein is provided. Polypeptides comprising the SARS-CoV-2 spike glycoprotein also are provided, as well as related nucleic acids, vectors, and compositions. The polypeptides, nucleic acids, vectors, and compositions can be used in methods of preventing, inhibiting, reducing, eliminating, protecting, or delaying the onset of an infection or an infectious clinical condition caused by coronavirus and methods for inducing an immune response against a coronavirus.
    Type: Grant
    Filed: September 2, 2020
    Date of Patent: August 31, 2021
    Assignee: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventor: William Paul Duprex