Patents by Inventor William R. Abrams

William R. Abrams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isothermal nucleic acid amplification reactor with integrated solid state membrane
    Patent number: 9976176
    Abstract: Provided are devices adapted to isolate, amplify, and detect nucleic acids that may be present in a biological sample. The devices can, in some embodiments, isolate, amplify, and detect nucleic acid in a single chamber. In other embodiments, the devices are adapted to isolate and amplify nucleic acids in a reaction chamber, after which the nucleic acids may be communicated to a pervious medium—such as a lateral flow strip—where the user may label and detect the nucleic acids.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: May 22, 2018
    Assignees: The Trustees of the University of Pennsylvania, New York University
    Inventors: Haim H. Bau, William R. Abrams, Eran Geva, Michael G. Mauk, Changchun Liu, Daniel Malamud, Xianbo Qiu
  • Isothermal Nucleic Acid Amplification Reactor With Integrated Solid State Membrane
    Publication number: 20170096702
    Abstract: Provided are devices adapted to isolate, amplify, and detect nucleic acids that may be present in a biological sample. The devices can, in some embodiments, isolate, amplify, and detect nucleic acid in a single chamber. In other embodiments, the devices are adapted to isolate and amplify nucleic acids in a reaction chamber, after which the nucleic acids may be communicated to a pervious medium—such as a lateral flow strip—where the user may label and detect the nucleic acids.
    Type: Application
    Filed: September 8, 2016
    Publication date: April 6, 2017
    Inventors: Haim H. Bau, William R. Abrams, Eran Geva, Michael G. Mauk, Changchun Liu, Daniel Malamud, Xianbo Qiu
  • Isothermal nucleic acid amplification reactor with integrated solid state membrane
    Patent number: 9476102
    Abstract: Provided are devices adapted to isolate, amplify, and detect nucleic acids that may be present in a biological sample. The devices can, in some embodiments, isolate, amplify, and detect nucleic acid in a single chamber. In other embodiments, the devices are adapted to isolate and amplify nucleic acids in a reaction chamber, after which the nucleic acids may be communicated to a pervious medium—such as a lateral flow strip—where the user may label and detect the nucleic acids.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: October 25, 2016
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Haim H. Bau, William R. Abrams, Eran Geva, Michael G. Mauk, Changchun Liu, Daneil Malamud, Xianbo Ceiu
  • ISOTHERMAL NUCLEIC ACID AMPLIFICATION REACTOR WITH INTEGRATED SOLID STATE MEMBRANE
    Publication number: 20140162244
    Abstract: Provided are devices adapted to isolate, amplify, and detect nucleic acids that may be present in a biological sample. The devices can, in some embodiments, isolate, amplify, and detect nucleic acid in a single chamber. In other embodiments, the devices are adapted to isolate and amplify nucleic acids in a reaction chamber, after which the nucleic acids may be communicated to a pervious medium—such as a lateral flow strip—where the user may label and detect the nucleic acids.
    Type: Application
    Filed: February 15, 2012
    Publication date: June 12, 2014
    Inventors: Haim H. Bau, William R. Abrams, Eran Geva, Michael G. Mauk, Changchun Liu, Daniel Malamud, Xianbo Ceiu
  • Method for sonic analysis of an anomaly in a seafloor topographic representation
    Patent number: 4751645
    Abstract: A method for sonic analyzation on-line and in real time or off-line in post processing of a topographic representation of a seafloor to provide the latitude and longitude of an object producing a corresponding anomaly appearance identified in a topographic respresentation generated from a side scan sonar tow fish includes in the on-line, real time analyzation the steps of sequentially touching the tip of a sonic digitizer stylus to a point on the line representation of the seafloor laterally opposite the appearance of the anomaly; to the leading edge and the trailing edge of the anomaly and to the tip of an acoustic shadow of the anomaly appearance; and, if length is desired, to the top and bottom edges of the anomaly appearance. A computer includes a set of instructions to calculate the desired information and is coupled to a host computer associated with a vessel which tows the sonar tow fish along a course covering an area of interest of the seafloor.
    Type: Grant
    Filed: August 12, 1986
    Date of Patent: June 14, 1988
    Inventors: William R. Abrams, John Spruance