Abstract: Organosilicon quaternary ammonium compounds, their formulations, including powdered and solid formulations, and methods of use to treat infections in humans and animals.

Abstract: Organosilicon quaternary ammonium compounds, their formulations, including powdered and solid formulations, and methods of use to treat infections in humans and animals.

Abstract: Organosilicon quaternary ammonium compounds, their formulations, including powdered and solid formulations, and methods of use to treat infections in humans and animals.

Abstract: Organosilicon quaternary ammonium compounds, their formulations, including lyophilized solid formulations, and methods of use to treat infections in humans and animals.

Abstract: An antimicrobial product and methods of use are provided. The antimicrobial product includes a water-soluble antimicrobial organosilane and various additional compound, including antibiotic and anti-inflammatory medications, antiseptics, and/or detergents. An example delivery system including a microcapsule encasing the product is also described. Methods of use include embedding a delivery system within an article, such as bandages, inserts or wound coverings, the microcapsule containing the product which is released by a mechanism and at a time particular to the intended use of the article. The methods include treating an infection on a substrate by disrupting an existing microbial colonization, penetrating existing biofilms, and/or killing existing microbes.

Abstract: An antimicrobial product and methods of use are provided. The antimicrobial product includes a water-soluble antimicrobial organosilane (3-(trihydroxysilyl) propyldimethyloctadecyl ammonium chloride) and various additional adjuvant compounds, including anti-inflammatory medications, antiseptics, penetrants and/or detergents. An example delivery system including a microcapsule encasing the product is also described. Methods of use include embedding a delivery system within an article, such as bandages, inserts or wound coverings, the microcapsule containing the product which is released by a mechanism and at a time particular to the intended use of the article. The methods include topically treating a biofilm infection on an animal tissue substrate by disrupting existing microbial biofilm growth, penetrating existing biofilms, thereby killing microbes, and also through providing residual bonded organosilane, then killing persister cell microbes that through degrees of dormancy have escaped being killed.

Abstract: An antimicrobial composition and methods of use are provided. This antimicrobial composition includes a water-soluble organosilane (3-(trihydroxysilyl) propyldimethyloctadecyl ammonium chloride) and additional adjuvant compounds, including anti-inflammatory medications, antiseptics, transdermal penetrants, nutrients and/or buffers, generally to be applied in liquid form to penetrate and kill biofilms that are infecting living vertebrates. The methods include topically treating an infection by penetrating and disrupting an existing biofilm and killing cells therein and killing any persister cells that, through degrees of dormancy or otherwise, have escaped being killed during the initial application of the antimicrobial composition.

Abstract: An antimicrobial composition and methods of use are provided. The antimicrobial composition includes a water-soluble antimicrobial organosilane ammonium compound and a sugar. The composition may be in liquid, foam, ointment or gel form. The composition may include anti-inflammatory medications, alcohol and/or steroids. The antimicrobial composition may be used to treat eye infections in humans and animals. The antimicrobial composition may be applied directly to the surface of the eye. The antimicrobial composition may further be used to treat ocular related articles, including contact lenses, contact cases, instruments, pads and the like. The antimicrobial composition may be applied directly to the surface of the ocular related article during and/or after manufacture.

Abstract: An antimicrobial product and methods of use are provided. The antimicrobial product includes a water-soluble antimicrobial organosilane and the product delivered in an alcohol, foam or gel state in some cases including various additional compounds including antibiotic and anti-inflammatory medications, antiseptics, and/or detergents. An example delivery system including a microcapsule encasing the product or a particle coated with the product is also described. Methods of use include embedding a delivery system within an article, the microcapsule containing the product which is released by a mechanism and at a time particular to the intended use of the article.

Abstract: An antimicrobial product and methods of use are provided. The antimicrobial product includes a water-soluble antimicrobial organosilane and various additional compound, including antibiotic and anti-inflammatory medications, antiseptics, and/or detergents. An example delivery system including a microcapsule encasing the product is also described. Methods of use include embedding a delivery system within an article, such as bandages, inserts or wound coverings, the microcapsule containing the product which is released by a mechanism and at a time particular to the intended use of the article. The methods include treating an infection on a substrate by disrupting an existing microbial colonization, penetrating existing biofilms, and/or killing existing microbes.