Patents by Inventor William R. Clark

William R. Clark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240335545
    Abstract: Disclosed are methods of treating graft versus host disease (GVHD) or treating ocular graft versus host disease (oGVHD). The methods may comprise administering a therapeutically effective amount of a composition comprising CCL20 locked dimer to a subject, e.g., a subject suffering from GVHD. Also disclosed are modified CCL20LD compositions comprising an unstructured polypeptide.
    Type: Application
    Filed: April 5, 2024
    Publication date: October 10, 2024
    Inventors: William R. Clarke, Brian F. Volkman, Francis C. Peterson, Michael B. Dwinell, Chad A. Koplinski
  • Publication number: 20240069161
    Abstract: In one embodiment, a lidar system includes a wavelength-tunable light source configured to emit pulses of light, each emitted pulse of light having a particular wavelength of multiple different wavelengths. The lidar system also includes a scanner configured to scan the emitted pulses of light across a field of regard of the lidar system. The scanner includes (i) a beam deflector configured to angularly deflect each emitted pulse of light along a first scan axis according to the particular wavelength of the emitted pulse of light and (ii) a scan mirror configured to scan the emitted pulses of light along a second scan axis different from the first scan axis. The lidar system further includes a receiver configured to detect a received pulse of light that includes a portion of one of the emitted pulses of light scattered by a target located a distance from the lidar system.
    Type: Application
    Filed: January 4, 2023
    Publication date: February 29, 2024
    Inventors: Joseph G. LaChapelle, Jason M. Eichenholz, Roger S. Cannon, Stephen D. Gaalema, William R. Clark, Alex Michael Sincore
  • Publication number: 20230213628
    Abstract: In one embodiment, a lidar system includes a light source configured to emit pulses of light and a scanner configured to scan the emitted pulses of light across a field of regard of the lidar system. The scanner includes (i) a beam deflector configured to direct each emitted pulse of light along a first scan axis and (ii) a scan mirror configured to scan the emitted pulses of light along a second scan axis different from the first scan axis. The lidar system also includes a receiver that includes a one-dimensional detector array that includes multiple detector elements arranged along a direction corresponding to the first scan axis. The receiver is configured to (i) detect a received pulse of light that includes a portion of one of the emitted pulses of light scattered by a target and (ii) determine a time of arrival of the received pulse of light.
    Type: Application
    Filed: January 4, 2023
    Publication date: July 6, 2023
    Inventors: Joseph G. LaChapelle, Jason M. Eichenholz, Roger S. Cannon, Stephen D. Gaalema, William R. Clark, Alex Michael Sincore
  • Patent number: 10055749
    Abstract: A service provider system remembers feedback by a user when the user selects an offer, a presented option, or other content from a page or display on a user device. The user is then taken to a new page or screen with details about the offer, option, or other content. When the user goes back to the original page or screen, the page is revised based on the user feedback. For example, a dialog box may pop up over the selected offer to ask the user whether the user accepted the offer or is not interested in the offer. If so, the offer disappears and subsequent pages may not show the selected offer again.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: August 21, 2018
    Assignee: PAYPAL, INC.
    Inventors: Egan Schulz, William R. Clarke, Javier Diaz-Infante
  • Patent number: 10004818
    Abstract: Methods and compositions utilizing ether and alkyl phospholipid ether analog compounds for treating cancer and imaging, monitoring, and detecting cancer stem cells in humans.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: June 26, 2018
    Assignee: CELLECTAR, Inc.
    Inventors: Jamey P. Weichert, Anatoly Pinchuk, Irawati Kandela, Marc Longino, William R. Clarke
  • Patent number: 9616140
    Abstract: The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and diagnostic methods utilizing these compounds.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: April 11, 2017
    Assignee: CELLECTAR BIOSCIENCES, INC.
    Inventors: Anatoly Pinchuk, Jamey P. Weichert, Marc Longino, Irawati Kandela, William R. Clarke
  • Publication number: 20160228588
    Abstract: Methods and compositions utilizing ether and alkyl phospholipid ether analog compounds for treating cancer and imaging, monitoring, and detecting cancer stem cells in humans.
    Type: Application
    Filed: April 15, 2016
    Publication date: August 11, 2016
    Inventors: Jamey P. Weichert, Anatoly Pinchuk, Irawati Kandela, Marc Longino, William R. Clarke
  • Patent number: 9339564
    Abstract: Methods and compositions utilizing ether and alkyl phospholipid ether analog compounds for treating cancer and imaging, monitoring, and detecting cancer stem cells in humans.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: May 17, 2016
    Assignee: CELLECTAR, INC.
    Inventors: Jamey P. Weichert, Anatoly Pinchuk, Irawati Kandela, Marc Longino, William R. Clarke
  • Publication number: 20160110781
    Abstract: There is provided systems and method for concession preordering for pickup or delivery during an event. A user may attend an event at a venue and have purchased admission for the event. Prior to attending the event, the user may establish a preorder for concessions available at the venue, such as popcorn for a movie or drinks at a concert or sports game. Once the user arrives at the venue, the preorder may be loaded to the concessions device so that a merchant viewing the preorder may fulfill the preorder by preparing the items in the preorder. The user may be detected at the venue through the user's communication device or when the user scans their ticket for entry to the venue. The user may be alerted when the order is prepared and instructed to visit a location or request the items to be delivered.
    Type: Application
    Filed: October 20, 2014
    Publication date: April 21, 2016
    Inventors: Teresa Elizabeth Bedel, Michael Hwang, Megan Marie Williams, William R. Clarke, April Van Scherpe
  • Publication number: 20160092797
    Abstract: Methods and systems for improving access to an attraction are described. A user pays for a purchase using a service provider. The service provider generates a pass to an attraction associated with the purchase. The pass can designate a future time and an access code for accessing the attraction. When the user returns at the assigned future time, the right of the user to the attraction at the assigned time is validated with the pass, and the user is granted immediate access to the attraction.
    Type: Application
    Filed: September 30, 2014
    Publication date: March 31, 2016
    Inventors: William R. Clarke, Michael Songnam Hwang, April Lynn Van Scherpe, Teresa Elizabeth Bedel, Megan Marie Williams
  • Publication number: 20150205657
    Abstract: Techniques for predicting failure of a storage device are described in various implementations. An example method that implements the techniques may include receiving, at an analysis system and from a computing system having a storage device, current diagnostic information associated with the storage device. The method may also include storing, using the analysis system, the current diagnostic information in a collection that includes historical diagnostic information associated with other storage devices of other computing systems. The method may also include predicting, using the analysis system, whether the storage device is likely to fail in a given time period based on the current diagnostic information and an estimated lifespan for storage devices that are of a same classification as the storage device, the estimated lifespan determined based on the collection.
    Type: Application
    Filed: September 28, 2012
    Publication date: July 23, 2015
    Inventor: William R. Clark
  • Patent number: 9022933
    Abstract: A computer readable storage medium having a computer program stored thereon and representing a set of instructions that when executed by a computer causes the computer to calculate a mapping function that provides a location of each sub-volume of an imaging volume as a function of time from ultrasound data and determine a respective acquisition window for each sub-volume of the imaging volume from the mapping function. The instructions also cause the computer to reconstruct an image of the imaging volume substantially free of motion artifacts from imaging data acquired from the imaging volume.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: May 5, 2015
    Assignee: General Electric Company
    Inventors: Jiang Hsieh, Michael John Barber, Brian J. Kost, William R. Clarke, Michael A. Juhl, Anne Lindsay Hall
  • Publication number: 20150044142
    Abstract: The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and diagnostic methods utilizing these compounds.
    Type: Application
    Filed: September 23, 2014
    Publication date: February 12, 2015
    Applicant: Cellectar, Inc.
    Inventors: Anatoly Pinchuk, Jamey P. Weichert, Marc Longino, Irawati Kandela, William R. Clarke
  • Patent number: 8871181
    Abstract: The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and diagnostic methods utilizing these compounds.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: October 28, 2014
    Assignee: Cellectar, Inc.
    Inventors: Anatoly Pinchuk, Jamey P. Weichert, Marc Longino, Irawati Kandela, William R. Clarke
  • Publication number: 20140289029
    Abstract: A service provider system remembers feedback by a user when the user selects an offer, a presented option, or other content from a page or display on a user device. The user is then taken to a new page or screen with details about the offer, option, or other content. When the user goes back to the original page or screen, the page is revised based on the user feedback. For example, a dialog box may pop up over the selected offer to ask the user whether the user accepted the offer or is not interested in the offer. If so, the offer disappears and subsequent pages may not show the selected offer again.
    Type: Application
    Filed: June 28, 2013
    Publication date: September 25, 2014
    Inventors: Egan Schulz, William R. Clarke, Javier Diaz-Infante
  • Publication number: 20130343991
    Abstract: Methods and compositions utilizing ether and alkyl phospholipid ether analog compounds for treating cancer and imaging, monitoring, and detecting cancer stem cells in humans.
    Type: Application
    Filed: May 6, 2013
    Publication date: December 26, 2013
    Applicant: CELLECTAR, INC.
    Inventors: Jamey P. Weichert, Anatoly Pinchuk, Irawati Kandela, Marc Longino, William R. Clarke
  • Publication number: 20120156133
    Abstract: The present invention provides phospholipid ether and alkyl phospholipid compounds and their combinations with other cancer therapy agents. More specifically, the invention relates to the use of phospholipid ether compounds comprising a “cold” isotope of iodine, e.g. 127I, or H, for treating cancer and combinations of phospholipid compounds comprising radioactive (i.e., “hot”) and non-radioactive (i.e., “cold”) isotopes of iodine.
    Type: Application
    Filed: February 23, 2012
    Publication date: June 21, 2012
    Applicant: Cellectar, Inc.
    Inventors: Anatoly Pinchuk, Marc Longino, Jamey P. Weichert, William R. Clarke, Abram M. Vaccaro, Irawati Kandela
  • Publication number: 20120128596
    Abstract: The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and diagnostic methods utilizing these compounds.
    Type: Application
    Filed: May 11, 2010
    Publication date: May 24, 2012
    Applicant: CELLECTAR, INC.
    Inventors: Anatoly Pinchuk, Jamey P. Weichert, Marc Longino, Irawati Kandela, William R. Clarke
  • Patent number: 8155729
    Abstract: Motion data is acquired simultaneously and in real-time with image data. The motion data provides accurate and near-instant information as to the state and position of an object prone to motion. The present invention is particularly applicable for cardiac CT or MR imaging and other physiologically gated acquisitions. In the context of cardiac imaging, the motion data includes information regarding size and location of the heart during the cardiac phases (diastole, systole, etc.) during each cardiac cycle.
    Type: Grant
    Filed: February 17, 2006
    Date of Patent: April 10, 2012
    Assignee: General Electric Company
    Inventors: Jiang Hsieh, Michael John Barber, Brian J. Kost, William R. Clarke, Michael A. Juhl, Anne Lindsay Hall
  • Publication number: 20110216957
    Abstract: A computer readable storage medium having a computer program stored thereon and representing a set of instructions that when executed by a computer causes the computer to calculate a mapping function that provides a location of each sub-volume of an imaging volume as a function of time from ultrasound data and determine a respective acquisition window for each sub-volume of the imaging volume from the mapping function. The instructions also cause the computer to reconstruct an image of the imaging volume substantially free of motion artifacts from imaging data acquired from the imaging volume.
    Type: Application
    Filed: May 19, 2011
    Publication date: September 8, 2011
    Inventors: Jiang Hsieh, Michael John Barber, Brian J. Kost, William R. Clarke, Michael A. Juhl, Anne Lindsay Hall