Patents by Inventor William R. Kenealy

William R. Kenealy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11753656
    Abstract: The present invention provides for novel metabolic pathways to reduce or modulate glycerol production and increase product formation. More specifically, the invention provides for a recombinant microorganism comprising one or more native and/or heterologous proteins that function to import glycerol and one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to convert a carbohydrate source, such as lignocellulose, to a product, such as ethanol, wherein the one or more native and/or heterologous proteins or enzymes is activated, upregulated, or downregulated.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: September 12, 2023
    Assignee: LALLEMAND HUNGARY LIQUIDITY MANAGEMENT LLC
    Inventors: Aaron Argyros, William R. Kenealy, Emily Stonehouse
  • Publication number: 20230159962
    Abstract: The present invention provides for novel metabolic pathways to reduce or modulate glycerol production and increase product formation. More specifically, the invention provides for a recombinant microorganism comprising one or more native and/or heterologous proteins that function to import glycerol and one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to convert a carbohydrate source, such as lignocellulose, to a product, such as ethanol, wherein the one or more native and/or heterologous proteins or enzymes is activated, upregulated, or downregulated.
    Type: Application
    Filed: August 8, 2022
    Publication date: May 25, 2023
    Applicant: LALLEMAND HUNGARY LIQUIDITY MANAGEMENT LLC
    Inventors: Aaron ARGYROS, William R. KENEALY, Emily STONEHOUSE
  • Publication number: 20220090045
    Abstract: The present disclosure provides for novel metabolic pathways to increase acetone and isopropanol formation. More specifically, the present disclosure provides for a recombinant microorganism comprising a plurality of first native and/or heterologous enzymes that function in a first engineered metabolic pathway to convert fructose-6-phosphate to acetyl-CoA and acetate (e.g., phosphoketolase and acetate kinase), wherein the plurality of first native and/or heterologous enzymes is activated, upregulated, or overexpressed. The recombinant microorganism further comprises a plurality of second native and/or heterologous enzymes that function in a second engineered metabolic pathways to convert acetyl-CoA and acetate to isopropanol (e.g., thiolase, CoA transferase and acetoacetate decarboxylase), wherein the plurality of second native and/or heterologous enzymes is activated, upregulated, or overexpressed. Also provided are methods for making isopropanol or acetone using the recombinant microorganisms.
    Type: Application
    Filed: December 10, 2021
    Publication date: March 24, 2022
    Inventors: Aaron Argyros, William R. Kenealy, Emily Stonehouse
  • Publication number: 20160194669
    Abstract: The present invention provides for novel metabolic pathways to reduce or modulate glycerol production and increase product formation. More specifically, the invention provides for a recombinant microorganism comprising one or more native and/or heterologous proteins that function to import glycerol and one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to convert a carbohydrate source, such as lignocellulose, to a product, such as ethanol, wherein the one or more native and/or heterologous proteins or enzymes is activated, upregulated, or downregulated.
    Type: Application
    Filed: August 15, 2014
    Publication date: July 7, 2016
    Inventors: Aaron Argyros, William R. Kenealy, Emily Stonehouse
  • Patent number: 8123904
    Abstract: The present invention provides a method for producing an MDF board from pulp from a fibrous lignocellulose material using a treatment or pretreatment step which exposes the material to oxalic acid or oxalic acid derivatives (particularly dialkyl ester derivatives, particularly in the vapor phase). The treated wood is then subjected to a sugar extraction wash and refined using any one of the several pulping methods to produce a final pulp product. Once this is done the pulp is used to make MDF boards having improved water repellency properties.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: February 28, 2012
    Assignees: Wisconsin Alumni Research Foundation, Biopulping International Inc., The United States of America as represented by the Secretary of Agriculture
    Inventors: Masood Akhtar, William R. Kenealy, Eric G. Horn, Ross E. Swaney, Jerrold Winandy
  • Publication number: 20100300634
    Abstract: The present invention provides a method for producing an MDF board from pulp from a fibrous lignocellulose material using a treatment or pretreatment step which exposes the material to oxalic acid or oxalic acid derivatives (particularly dialkyl ester derivatives, particularly in the vapor phase). The treated wood is then subjected to a sugar extraction wash and refined using any one of the several pulping methods to produce a final pulp product. Once this is done the pulp is used to make MDF boards having improved water repellency properties.
    Type: Application
    Filed: August 11, 2010
    Publication date: December 2, 2010
    Inventors: Masood Akhtar, William R. Kenealy, Eric G. Horn, Ross E. Swaney, Jerrold Winandy
  • Publication number: 20080264588
    Abstract: The present invention provides a method for producing an MDF board from pulp from a fibrous lignocellulose material using a treatment or pretreatment step which exposes the material to oxalic acid or oxalic acid derivatives (particularly dialkyl ester derivatives, particularly in the vapor phase). The treated wood is then subjected to a sugar extraction wash and refined using any one of the several pulping methods to produce a final pulp product. Once this is done the pulp is used to make MDF boards having improved water repellency properties.
    Type: Application
    Filed: August 31, 2007
    Publication date: October 30, 2008
    Inventors: Masood Akhtar, William R. Kenealy, Eric G. Horn, Ross E. Swaney, Jerrold Winandy
  • Patent number: 5562905
    Abstract: A chemically synthesized 15 amino acid peptide designated peptide 1-69, which has the sequence of amino acids numbers 308 to 322 (RIQRGPGRAFVTIGK) of the human immunodeficiency virus-1 (HIV-1) IIIB env-coded protein, was used to immunize animals. Peptide 1-69 elicited in immunized animals antibodies that block HIV proliferation and block HIV-induced cell fusion in cell culture.
    Type: Grant
    Filed: March 20, 1989
    Date of Patent: October 8, 1996
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: William R. Kenealy, Stephen R. Petteway, Paul J. Durda