Patents by Inventor William R. Levis

William R. Levis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200101028
    Abstract: The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.
    Type: Application
    Filed: April 8, 2019
    Publication date: April 2, 2020
    Applicant: Phio Pharmaceuticals Corp.
    Inventors: William R. Levis, Leonard L. Kaplan, John G. Callahan
  • Patent number: 10300027
    Abstract: The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: May 28, 2019
    Assignee: Phio Pharmaceuticals Corp.
    Inventors: William R. Levis, Leonard L. Kaplan, John G. Callahan
  • Publication number: 20150057362
    Abstract: The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.
    Type: Application
    Filed: November 4, 2014
    Publication date: February 26, 2015
    Inventors: William R. Levis, Leonard L. Kaplan, John G. Callahan
  • Patent number: 8835619
    Abstract: The present invention is directed to heat shock proteins from Mycobacterium leprae as well as their encoding polynucleotides and vectors and host cells containing these polynucleotides. These heat shock proteins and their encoding polynucleotides are useful in detection of Mycobacterium leprae. In addition, the heat shock protein can be used as an adjuvant in a pharmaceutical composition containing an antigen to induce or enhance the immune response against the antigen. Further, the heat shock protein may be used to treat atopic conditions or as a vaccine against Mycobacterium leprae. Alternatively, the heat shock protein can be used to form a fusion protein with an antigen to induce or enhance the immune response against the antigen.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: September 16, 2014
    Assignee: New York University
    Inventors: William R. Levis, Frank T. Martiniuk
  • Publication number: 20110268761
    Abstract: The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.
    Type: Application
    Filed: February 25, 2011
    Publication date: November 3, 2011
    Inventors: William R. Levis, Leonard L. Kaplan, John G. Callahan
  • Publication number: 20100136016
    Abstract: The present invention is directed to heat shock proteins from Mycobacterium leprae as well as their encoding polynucleotides and vectors and host cells containing these polynucleotides. These heat shock proteins and their encoding polynucleotides are useful in detection of Mycobacterium leprae. In addition, the heat shock protein can be used as an adjuvant in a pharmaceutical composition containing an antigen to induce or enhance the immune response against the antigen. Further, the heat shock protein may be used to treat atopic conditions or as a vaccine against Mycobacterium leprae. Alternatively, the heat shock protein can be used to form a fusion protein with an antigen to induce or enhance the immune response against the antigen.
    Type: Application
    Filed: November 23, 2009
    Publication date: June 3, 2010
    Applicant: NEW YORK UNIVERSITY
    Inventors: William R. LEVIS, Frank T. MARTINIUK
  • Patent number: 7622121
    Abstract: The present invention is directed to heat shock proteins from Mycobacterium leprae as well as their encoding polynucleotides and vectors and host cells containing these polynucleotides. These heat shock proteins and their encoding polynucleotides are useful in detection of Mycobacterium leprae. In addition, the heat shock protein can be used as an adjuvant in a pharmaceutical composition containing an antigen to induce or enhance the immune response against the antigen. Further, the heat shock protein may be used to treat atopic conditions or as a vaccine against Mycobacterium leprae. Alternatively, the heat shock protein can be used to form a fusion protein with an antigen to induce or enhance the immune response against the antigen.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: November 24, 2009
    Assignee: New York University
    Inventors: William R. Levis, Frank T. Martiniuk
  • Patent number: 6455586
    Abstract: Topical drug compositions, containing contact sensitizing agents as the active components of the subject patent compositions, can provide a pharmacological action that induces a delayed hypersensitization reaction resulting in stimulation of cell mediated immunity when applied to the skin. The preferred composition contains, but is not limited to, Diphenylcyclpropenone as a preferred embodiment of the class of contact sensitizing drugs applied to the skin in an optimally prepared pharmaceutical formulation with controlled absorption properties to reach the peripheral circulation resulting in increases in CD4+ helper T cells of benefit to immunocompromised patients.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: September 24, 2002
    Inventors: Leonard L. Kaplan, William R. Levis
  • Publication number: 20020128326
    Abstract: Topical drug compositions, containing contact sensitizing agents as the active components of the subject patent compositions, can provide a pharmacological action that induces a delayed hypersensitization reaction resulting in stimulation of cell mediated immunity when applied to the skin. The preferred composition contains, but is not limited to, Diphenylcyclpropenone as a preferred embodiment of the class of contact sensitizing drugs applied to the skin in an optimally prepared pharmaceutical formulation with controlled absorption properties to reach the peripheral circulation resulting in increases in CD4+ helper T cells of benefit to immunocompromised patients.
    Type: Application
    Filed: December 13, 1999
    Publication date: September 12, 2002
    Inventors: LEONARD L. KAPLAN, WILLIAM R. LEVIS