Patents by Inventor William R. Moore
William R. Moore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12138273Abstract: Sustained-release abiraterone prodrug formulations, methods, and kits for parenteral administration to a subject having a sex hormone-dependent benign or malignant disorder such as prostate cancer, a syndrome due to androgen excess, and/or a syndrome due to glucocorticoid excess such as hypercortisolemia.Type: GrantFiled: January 19, 2023Date of Patent: November 12, 2024Assignee: PROPELLA THERAPEUTICS, INC.Inventors: Matthew J. Sharp, William R. Moore, Jr.
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Patent number: 11957696Abstract: Sustained-release abiraterone prodrug formulations, methods, and kits for parenteral administration to a subject having a sex hormone-dependent benign or malignant disorder such as prostate cancer, an androgen receptor driven cancer, a syndrome due to androgen excess, and/or a syndrome due to glucocorticoid excess such as hypercortisolemia.Type: GrantFiled: February 14, 2022Date of Patent: April 16, 2024Assignee: PROPELLA THERAPEUTICS, INC.Inventors: Matthew J. Sharp, William R. Moore, Jr.
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Publication number: 20230196457Abstract: A system for managing investment information and knowledge is disclosed, comprising at least one database configured to store a plurality of user and stock market information. A portfolio database stores portfolio information for a plurality of users, accessible via a computing device. A teaching system is in operable communication with a teaching database and a teaching server to provide instructional information. An evaluation system is in operable communication with an evaluation database and an evaluation server to provide evaluations related to one or more trading techniques.Type: ApplicationFiled: December 21, 2021Publication date: June 22, 2023Inventors: Hunter Slay, William R. Moore
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Patent number: 11559534Abstract: Sustained-release abiraterone prodrug formulations, methods, and kits for parenteral administration to a subject having a sex hormone-dependent benign or malignant disorder such as prostate cancer, a syndrome due to androgen excess, and/or a syndrome due to glucocorticoid excess such as hypercortisolemia.Type: GrantFiled: August 10, 2020Date of Patent: January 24, 2023Assignee: Propella Therapeutics, Inc.Inventors: Matthew J. Sharp, William R. Moore, Jr.
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Publication number: 20220265681Abstract: Sustained-release abiraterone prodrug formulations, methods, and kits for parenteral administration to a subject having a sex hormone-dependent benign or malignant disorder such as prostate cancer, an androgen receptor driven cancer, a syndrome due to androgen excess, and/or a syndrome due to glucocorticoid excess such as hypercortisolemia.Type: ApplicationFiled: February 14, 2022Publication date: August 25, 2022Inventors: Matthew J. SHARP, William R. Moore, JR.
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Publication number: 20200368255Abstract: Sustained-release abiraterone prodrug formulations, methods, and kits for parenteral administration to a subject having a sex hormone-dependent benign or malignant disorder such as prostate cancer, a syndrome due to androgen excess, and/or a syndrome due to glucocorticoid excess such as hypercortisolemia.Type: ApplicationFiled: August 10, 2020Publication date: November 26, 2020Inventors: Matthew J. SHARP, William R. Moore, JR.
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Patent number: 10792292Abstract: Sustained-release abiraterone prodrug formulations, methods, and kits for parenteral administration to a subject having a sex hormone-dependent benign or malignant disorder such as prostate cancer, a syndrome due to androgen excess, and/or a syndrome due to glucocorticoid excess such as hypercortisolemia.Type: GrantFiled: March 4, 2020Date of Patent: October 6, 2020Assignee: Propella Therapeutics, Inc.Inventors: Matthew J. Sharp, William R. Moore, Jr.
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Patent number: 10427740Abstract: A system for hanging a split outer side panel on a rack in a manufacturing environment, the split outer side panel includes a first part having a rear section, a top section, and a rear portion of a side sill, and a second part having an A-pillar, a B-pillar, and a front portion of the side sill. The system includes a jig for hanging the first part of the split outer side panel. The jig includes a first keyhole pin extending from a first surface of the jig, the first keyhole pin being received by a first keyhole in the first part, and a second keyhole pin extending from a first surface of the jig, the second keyhole pin being received by a second keyhole in the first part.Type: GrantFiled: October 21, 2015Date of Patent: October 1, 2019Assignee: Honda Motor Co., Ltd.Inventors: William R Moore, David P Tracey, John McQueen
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Patent number: 10322444Abstract: An apparatus for rotating an inner stamped part with respect to an outer stamped part is provided. The inner stamped part is nested within an aperture formed within the outer stamped part. The apparatus includes a plurality of grippers that include at least a first gripper positioned at a first edge of the inner stamped part and a second gripper positioned at a second edge of the inner stamped part opposite to the first edge. The plurality of grippers is configured to grip the inner stamped part at the first edge and the second edge, respectively. The plurality of grippers is further configured to rotate the gripped inner stamped part about an axis of rotation. The axis of rotation intersects the first gripper and the second gripper. The plurality of grippers is also configured to open to release the inner stamped part.Type: GrantFiled: January 17, 2017Date of Patent: June 18, 2019Assignee: Honda Motor Co., Ltd.Inventors: William R. Moore, Emily Germann, Paul Adams Thompson, John Scott McQueen, Jeffrey Frank Teubl
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Publication number: 20180201451Abstract: An apparatus for rotating an inner stamped part with respect to an outer stamped part is provided. The inner stamped part is nested within an aperture formed within the outer stamped part. The apparatus includes a plurality of grippers that include at least a first gripper positioned at a first edge of the inner stamped part and a second gripper positioned at a second edge of the inner stamped part opposite to the first edge. The plurality of grippers is configured to grip the inner stamped part at the first edge and the second edge, respectively. The plurality of grippers is further configured to rotate the gripped inner stamped part about an axis of rotation. The axis of rotation intersects the first gripper and the second gripper. The plurality of grippers is also configured to open to release the inner stamped part.Type: ApplicationFiled: January 17, 2017Publication date: July 19, 2018Inventors: William R. Moore, Emily Germann, Paul Adams Thompson, John Scott McQueen, Jeffrey Frank Teubl
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Patent number: 9415433Abstract: Disclosed herein is a sheet metal stamping device and method for substantially inhibiting recoil from a neutral stamped position of a scrap part region. A sheet metal stamping device for stamping a sheet metal part comprising a first die body and a second is provided wherein the first die body and the second die body are in operable communication for forming the sheet metal part from a sheet metal blank. The sheet metal part includes at least one scrap region formed therein which is prone to recoil from a neutral stamped position. The first die body and the second die body have complementary elongate bead-forming regions located for forming an elongate bead region in the scrap region. And, the elongate bead-forming regions are configured such that the elongate bead substantially inhibits recoil or springback of the scrap region from the neutral stamped position when the scrap region is severed from the part.Type: GrantFiled: June 29, 2010Date of Patent: August 16, 2016Assignee: HONDA MOTOR CO., LTD.Inventor: William R. Moore
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Patent number: 9409222Abstract: Disclosed herein is a sheet metal stamping device and methods for reducing the size of a blank required for producing a stamped part therefrom than is conventionally possible. The device utilizes an intermediate clamp section with projections having clamping formations located thereon which complement clamping formations located on a first die section. The intermediate clamp section projections allow for the use of a smaller blank size as less addendum material is required to secure the blank during the stamping process. The blank is secured using the intermediate clamp section and the first die section prior to the second die section engaging the blank to stamp the part. In some embodiments, retention beads resultant from the clamping process may remain in the stamped part, that being inside a trim line. Furthermore, in some embodiments, a blank shifter may be provided to locate the blank between the die sections prior to clamping.Type: GrantFiled: February 25, 2011Date of Patent: August 9, 2016Assignee: HONDA MOTOR CO., LTD.Inventors: William R. Moore, Kevin P. Glenn
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Publication number: 20120318034Abstract: Disclosed herein is a sheet metal stamping device and methods for reducing the size of a blank required for producing a stamped part therefrom than is conventionally possible. The device utilizes an intermediate clamp section with projections having clamping formations located thereon which complement clamping formations located on a first die section. The intermediate clamp section projections allow for the use of a smaller blank size as less addendum material is required to secure the blank during the stamping process. The blank is secured using the intermediate clamp section and the first die section prior to the second die section engaging the blank to stamp the part. In some embodiments, retention beads resultant from the clamping process may remain in the stamped part, that being inside a trim line. Furthermore, in some embodiments, a blank shifter may be provided to locate the blank between the die sections prior to clamping.Type: ApplicationFiled: February 25, 2011Publication date: December 20, 2012Applicant: HONDA MOTOR CO., LTD.Inventors: William R. Moore, Kevin P. Glenn
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Patent number: 7612200Abstract: The present invention is directed to a compound having the formula wherein R1, R2, R3, R4, G, and Q are defined herein. The compounds of the present invention are useful as inhibitors of protein kinases. The present invention is also directed to compositions comprising a compound according to the above formula. The present invention is also directed to compounds that stabilize the open conformation of a protein kinase, a crystallized protein kinase in the open conformation, and uses thereof. The compounds and compositions described herein are useful for treating and preventing an inflammatory condition or disease.Type: GrantFiled: December 7, 2005Date of Patent: November 3, 2009Assignee: Locus Pharmaceuticals, Inc.Inventors: Enrique Luis Michelotti, William R. Moore, Jr., Eric Bruce Springman
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Publication number: 20090192307Abstract: The present invention is directed to a compound having the formula wherein R1, R2, R3, R4, G, and Q are defined herein. The compounds of the present invention are useful as inhibitors of protein kinases. The present invention is also directed to compositions comprising a compound according to the above formula. The present invention is also directed to compounds that stabilize the open conformation of a protein kinase, a crystallized protein kinase in the open conformation, and uses thereof. The compounds and compositions described herein are useful for treating and preventing an inflammatory condition or disease.Type: ApplicationFiled: December 7, 2005Publication date: July 30, 2009Inventors: Enrique Luis Michelotti, William R. Moore, JR., Eric Bruce Springman
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Publication number: 20080280891Abstract: The present invention is in the area of novel compounds and salts thereof, their syntheses, and their use as anti-cancer agents. The compounds include compounds of Formula I: and solvates, hydrates and pharmaceutically-acceptable salts thereof, wherein A1 is N or CR1; A3 is N or CR3; A5 is N or CR5; R1, R3-R6 and L are defined in the specification; n is 0 or 1; and X is an optionally-substituted aryl group having 6-10 carbons in the ring portion, an optionally-substituted 6-membered heteroaryl group having 1-3 nitrogen atoms in the ring portion, an optionally-substituted 5-membered heteroaryl group having 0-4 nitrogen atoms in the ring portion and optionally having 1 sulfur atom or 1 oxygen atom in the ring portion, or an optionally-substituted heteroaryl group in which a 6-membered ring is fused either to a 5-membered ring or to a 6-membered ring, wherein in each case 1, 2, 3 or 4 ring atoms are heteroatoms independently selected from nitrogen, oxygen and sulfur.Type: ApplicationFiled: June 27, 2007Publication date: November 13, 2008Applicant: Locus Pharmaceuticals, Inc.Inventors: Martha Kelly, Younghee Lee, Bin Liu, Ted Fujimoto, Joel Freundlich, Bruce D. Dorsey, Gary A. Flynn, Arifa Husain, William R. Moore, Jr.
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Publication number: 20040190799Abstract: A discharge bag for flowable materials is disclosed, having a side discharge spout near the bottom of the bag, allowing for discharge without the requirement for the bag to be hoisted by a forklift or other means, for discharging the materials contained within. The side discharge bag can be conveniently used with a frame assembly that further facilitates the discharge of flowable materials stored in the bag.Type: ApplicationFiled: July 22, 2003Publication date: September 30, 2004Applicant: General Electric CompanyInventors: Kief Hess, William R. Moore, Steve L. Suuk, Michael P. Dawley, Thad P. Leister
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Patent number: 6355460Abstract: The present invention relates to serine protease inhibitors having a P site binding moiety and a divalent cation(s) chelating moiety which are pre-prepared as divalent cation(s) complexes or combined with the serine protease in the presence of divalent cation(s) and methods for identifying and using the inhibitors. The compounds are shown to have high inhibitory activity when complexed to divalent cation(s) and are useful in various processes associated with serine protease isolation and inhibition.Type: GrantFiled: July 12, 1999Date of Patent: March 12, 2002Assignee: Axys Pharmaceuticals, Inc.Inventors: James M. Clark, Kyle Elrod, Thomas E. Jenkins, Bradley A. Katz, William R. Moore, Robert M. Stroud
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Patent number: 6255091Abstract: A method is presented for determining if the inhibition of metal mediated serine proteases can be potentiated by cobalt or zinc ions.Type: GrantFiled: November 19, 1996Date of Patent: July 3, 2001Assignees: AXYS Pharmaceuticals, Inc., The Regents of the University of CaliforniaInventors: James M. Clark, Kyle Elrod, Thomas E. Jenkins, Bradley A. Katz, William R. Moore, Robert M. Stroud
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Patent number: 5489600Abstract: The present invention relates to piperidyl amides which are useful as inhibitors of cholesterol biosynthesis and as agents which lower total serum cholesterol in patients in need thereof.Type: GrantFiled: May 25, 1994Date of Patent: February 6, 1996Inventors: Marion W. Wannamaker, William A. VanSickle, William R. Moore