Patents by Inventor William R. Morrone

William R. Morrone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzothiazepine anti-seizure method
    Patent number: 4963545
    Abstract: Seizures are ameliorated with certain benzothiazepines.
    Type: Grant
    Filed: November 22, 1989
    Date of Patent: October 16, 1990
    Assignee: Marion Laboratories, Inc.
    Inventors: Ray H. Zobrist, William R. Morrone
  • Method of ameliorating epileptic seizures
    Patent number: 4879289
    Abstract: A method for ameliorating or preventing generalized tonic-clonic type epileptic seizures in mammals is provided. The method involves systemically administering to a mammal in need of such treatment a compound having the formula ##STR1## wherein X is hydrogen, a lower straight chain or branched alkyl, hydroxy, a halogen or a lower straight chain or branched alkyl halide; Y is a lower straight chain or branched alkyl; R.sub.1 is hydrogen, hydroxy or acetyloxy; R.sub.2 and R.sub.3 are each a lower straight chain or branched alkyl or a non-aromatic cycloalkyl or together are a heterocyclic, and pharmaceutically acceptable salts thereof in an amount effective to ameliorate or prevent generalized tonic-clonic type seizures. Preferred compounds are those in which X is hydrogen or 8-chloro, Y is ethyl, R.sub.1 is acetyloxy and R.sub.2 and R.sub.3 are each methyl.
    Type: Grant
    Filed: May 24, 1988
    Date of Patent: November 7, 1989
    Assignee: Marion Laboratories, Inc.
    Inventors: Ray H. Zobrist, William R. Morrone
  • Benzothiazepine anti-seizure method
    Patent number: RE35095
    Abstract: Seizures are ameliorated with certain benzothiazepines.
    Type: Grant
    Filed: September 9, 1992
    Date of Patent: November 21, 1995
    Assignee: Marion Laboratories, Inc.
    Inventors: Ray H. Zobrist, William R. Morrone