Patents by Inventor William R. N. Williamson

William R. N. Williamson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4281017
    Abstract: Compounds of formula I ##STR1## wherein either R.sup.1 and R.sup.2 are both hydrogen or R.sup.1 and R.sup.2, taken together, represent a group of formula (a): ##STR2## in which R.sup.5 is hydrogen, halogen or C.sub.1-4 alkyl, R.sup.3 is hydrogen or a group of formula (b): ##STR3## in which R.sup.6 is hydrogen or C.sub.1-4 alkyl, and R.sup.4 is hydrogen or a group of formula --CHR.sup.7 COOH, where R.sup.7 is hydrogen or C.sub.1-4 alkyl,provided that:(i) when R.sup.3 is a group of formula (b), then R.sup.1, R.sup.2 and R.sup.4 are all hydrogen,(ii) when R.sup.3 is hydrogen, then R.sub.4 is --CHR.sup.7 COOH, and(iii) when R.sup.1 and R.sup.2, together, represent a group of formula (a), then R.sub.3 is hydrogen;possess pharmacological activity, in particular anti-inflammatory activity and are particularly useful in treatment of rheumatoid arthritis.
    Type: Grant
    Filed: September 10, 1979
    Date of Patent: July 28, 1981
    Assignee: Lilly Industries Limited
    Inventor: William R. N. Williamson
  • Patent number: 4246281
    Abstract: Acenaphthenes of formula (I) ##STR1## where Ph represents an optionally substituted phenyl group and wherein R.sup.1 represents hydrogen or C.sub.1-4 alkyl are useful anti-inflammatory agents.
    Type: Grant
    Filed: September 10, 1979
    Date of Patent: January 20, 1981
    Assignee: Lilly Industries Limited
    Inventor: William R. N. Williamson
  • Patent number: 4166818
    Abstract: Acylamino heteroaryl compounds in which the heteroaryl nucleus is a 1,2,4-oxadiazole or 1,2,4-thiadiazole nucelus, methods of making the compounds and pharmaceutical formulations containing the compounds. The compounds have anti-allergy activity.
    Type: Grant
    Filed: October 11, 1977
    Date of Patent: September 4, 1979
    Assignee: Lilly Industries Limited
    Inventors: William J. Ross, John P. Verge, William R. N. Williamson
  • Patent number: 4163048
    Abstract: Acylamino heteroaryl compounds in which the heteroaryl nucleus is a 1,2,4-oxadiazole or 1,2,4-thiadiazole nucleus, methods of making the compounds and pharmaceutical formulations containing the compounds. The compounds having anti-allergy activity.
    Type: Grant
    Filed: June 13, 1977
    Date of Patent: July 31, 1979
    Assignee: Lilly Industries Limited
    Inventors: William J. Ross, John P. Verge, William R. N. Williamson
  • Patent number: 4158659
    Abstract: Acylamino heteroaryl compounds in which the heteroaryl nucleus is a 1,3,4-oxadiazole or 1,3,4-thiadiazole nucleus, methods of making the compounds and pharmaceutical formulations containing the compounds. The compounds have anti-allergy activity.
    Type: Grant
    Filed: October 7, 1977
    Date of Patent: June 19, 1979
    Assignee: Lilly Industries Limited
    Inventors: William J. Ross, John P. Verge, William R. N. Williamson
  • Patent number: 4152442
    Abstract: Acylamino heteroaryl compounds in which the heteroaryl nucleus is a 1,3,4-oxadiazole or 1,3,4-thiadiazole nucleus, methods of making the compounds and pharmaceutical formulations containing the compounds. The compounds have anti-allergy activity.
    Type: Grant
    Filed: June 22, 1977
    Date of Patent: May 1, 1979
    Assignee: Lilly Industries Limited
    Inventors: William J. Ross, John P. Verge, William R. N. Williamson
  • Patent number: 4141995
    Abstract: o-Hydroxybenzophenones and derivatives thereof are described together with a process for their production. The compounds have anti-allergy activity and are characterized by the presence of an alkyl substituent on the hydroxyphenyl ring.
    Type: Grant
    Filed: September 2, 1977
    Date of Patent: February 27, 1979
    Assignee: Lilly Industries Limited
    Inventors: John C. Saunders, William R. N. Williamson
  • Patent number: 4134993
    Abstract: Novel benzophenone derivatives having anti-allergy activity, and pharmaceutical formulations and methods of treatment utilizing benzophenone derivatives.
    Type: Grant
    Filed: October 11, 1977
    Date of Patent: January 16, 1979
    Assignee: Eli Lilly and Company
    Inventors: Delme Evans, John C. Saunders, William R. N. Williamson
  • Patent number: 4131682
    Abstract: Novel heteroaryl ketone derivatives, specifically a class of phenyl heteroaryl methanone derivatives, having anti-allergy activity, pharmaceutical formulations containing diphenylmethane derivatives and methods of treatment utilizing such derivatives.
    Type: Grant
    Filed: October 11, 1977
    Date of Patent: December 26, 1978
    Assignee: Lilly Industries Limited
    Inventors: Delme Evans, John C. Saunders, William R. N. Williamson