Patents by Inventor William R. Perrault

William R. Perrault has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID FORMS OF TERT-BUTYL (S)-2((2S,3R)-1-AMINO-3-HYDROXY-1-OXOBU TAN-2-YL)-1-OXO-2, 5-DIAZASPIRO [3.4] OCTAN E-5-CARBOXYLATE AND METHODS OF PREPARING THEM
    Publication number: 20220267341
    Abstract: Solid state forms of tert-buty 1 (S)-2-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-oxo-2,5-diazaspiro[3.4] octane-5-carboxylate, pharmaceutical compositions, preparation, and uses thereof.
    Type: Application
    Filed: June 23, 2020
    Publication date: August 25, 2022
    Inventors: Xiaoda YUAN, Shaoxin FENG, Danny T. DING, William R. PERRAULT
  • PROCESSES AND INTERMEDIATES FOR PRODUCING DIAZASPIRO LACTAM COMPOUNDS
    Publication number: 20220259217
    Abstract: Processes for producing diazaspiro lactam compounds and intermediates useful in the processes.
    Type: Application
    Filed: June 23, 2020
    Publication date: August 18, 2022
    Inventors: Danny T. DINH, William R. PERRAULT, Khalid DIKER
  • Enamines and diastereo-selective reduction of enamines
    Patent number: 10501483
    Abstract: Described herein is a compound having a chemical structure of Formula A: wherein m, p, q, W, Z, Y, X1, X2, R1, R2, R3 and R4 are as defined herein. A diastereo-selective reduction of the compound comprising contacting the compound of Formula A with a reducing agent in an aprotic polar or non-polar solvent is also described.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: December 10, 2019
    Assignee: ALLERGAN, INC.
    Inventors: Danny T. Dinh, William R. Perrault
  • ENAMINES AND DIASTEREO-SELECTIVE REDUCTION OF ENAMINES
    Publication number: 20190119304
    Abstract: Described herein is a compound having a chemical structure of Formula A: wherein m, p, q, W, Z, Y, X1, X2, R1, R2, R3 and R4 are as defined herein. A diastereo-selective reduction of the compound comprising contacting the compound of Formula A with a reducing agent in an aprotic polar or non-polar solvent is also described.
    Type: Application
    Filed: October 23, 2018
    Publication date: April 25, 2019
    Inventors: Danny T. Dinh, William R. Perrault
  • Process to prepare oxazolidinones
    Patent number: 7087784
    Abstract: The present invention relates to a one-step process to prepare pharmacologically active 2-oxo-5-oxazolidinylmethylacetamides.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: August 8, 2006
    Assignee: Pharmacia & Upjohn
    Inventors: William R. Perrault, Bruce Allen Pearlman, Delara B. Godrej
  • Oxazolidinone compounds
    Patent number: 6998420
    Abstract: Methods of synthesizing pharmacologically useful oxazolidinones are disclosed, and, in particular, a method of manufacturing a 5-(tert-butylcarbamoyl)-aminomethyl-oxazolidinone by condensing a carbamate with a tert-butylcarbamoyl protected derivative of glycidylamine or 3-amino-1-halopropanol.
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: February 14, 2006
    Assignee: Pharmacia & Upjohn Company
    Inventors: William R. Perrault, Robert C. Gadwood
  • Process to prepare oxazolidinones
    Patent number: 6887995
    Abstract: The present invention relates to a one-step process to prepare pharmacologically active 2-oxo-5-oxazolidinylmethylacetamides.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: May 3, 2005
    Assignee: Pharmacia & Upjohn Company
    Inventors: William R. Perrault, Bruce Allen Pearlman, Delara B. Godrej
  • 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamide antiviral agents
    Patent number: 6878705
    Abstract: The invention provides a compound of formula I: wherein G, R2, R3, and R4 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediates useful for preparing such compounds or salts, and methods of treating a herpesvirus infection using such compounds or salts.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: April 12, 2005
    Assignee: Pfizer
    Inventors: Michele M. Cudahy, Mark E. Schnute, Steven P. Tanis, William R. Perrault, Paul Matthew Herrinton, Sajiv K. Nair
  • 4-OXO-4,7-DIHYDROFURO[2,3-B]PYRIDINE-5-CARBOXAMIDE ANTIVIRAL AGENTS
    Publication number: 20040259907
    Abstract: The invention provides a compound of formula I: 1
    Type: Application
    Filed: January 14, 2003
    Publication date: December 23, 2004
    Inventors: Michele M. Cudahy, Mark E. Schnute, Steven P. Tanis, William R. Perrault, Paul Matthew Herrinton, Sajiv K. Nair
  • Methods of producing oxazolidinone compounds
    Patent number: 6833453
    Abstract: Methods of synthesizing pharmacologically useful oxazolidinones are disclosed, and, in particular, a method of manufacturing a 5-(tert-butylcarbamoyl)-aminomethyl-oxazolidinone by condensing a carbamate with a tert-butylcarbamoyl protected derivative of glycidylamine or 3-amino-1-halopropanol.
    Type: Grant
    Filed: October 17, 2001
    Date of Patent: December 21, 2004
    Assignee: Pharmacia & Upjohn Company
    Inventors: William R. Perrault, Robert C. Gadwood
  • Process to prepare oxazolidinones
    Publication number: 20040220407
    Abstract: The present invention relates to a one-step process to prepare pharmacologically active 2-oxo-5-oxazolidinylmethylacetamides.
    Type: Application
    Filed: March 25, 2004
    Publication date: November 4, 2004
    Inventors: William R. Perrault, Bruce Allen Pearlman, Delara B. Godrej
  • Methods of producing oxazolidinone compounds
    Publication number: 20040143131
    Abstract: Methods of synthesizing pharmacologically useful oxazolidinones are disclosed, and, in particular, a method of manufacturing a 5-(tert-butylcarbamoyl)-aminomethyl-oxazolidinone by condensing a carbamate with a tert-butylcarbamoyl protected derivative of glycidylamine or 3-amino-1-halopropanol.
    Type: Application
    Filed: December 23, 2003
    Publication date: July 22, 2004
    Applicant: PHARMACIA & UPJOHN COMPANY
    Inventors: William R. Perrault, Robert C. Gadwood
  • Heteroaryl-ethanolamine derivatives as antiviral agents
    Publication number: 20040110787
    Abstract: The present invention provides a compound of formula as described herein, which are useful as antiviral agents, in particular, as agents against viruses of the herpes family.
    Type: Application
    Filed: August 27, 2003
    Publication date: June 10, 2004
    Inventors: Mark E. Schnute, Michele M. Cudahy, David John Anderson, Thomas M. Judge, Thomas J. Fleck, Paul Matthew Herrinton, Sajiv K. Nair, Allen Scott, William R. Perrault, Steve P. Tanis, James A. Nieman, Sarah A. Collier, Bruce F. Fleck
  • Pyridoquinoxaline antivirals
    Publication number: 20040106596
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: November 25, 2003
    Publication date: June 3, 2004
    Inventor: William R. Perrault
  • PYRIDOQUINOXALINE ANTIVIRALS
    Publication number: 20030130255
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: December 19, 2002
    Publication date: July 10, 2003
    Inventors: Joseph Walter Strohbach, Steven P. Tanis, Malcolm Wilson Moon, William R. Perrault
  • Process to prepare oxazolidinones
    Publication number: 20020169312
    Abstract: The present invention relates to a one-step process to prepare pharmacologically active 2-oxo-5-oxazolidinylmethylacetamides.
    Type: Application
    Filed: April 15, 2002
    Publication date: November 14, 2002
    Inventors: William R. Perrault, Bruce Allen Pearlman, Delara B. Godrej
  • Methods of producing oxazolidinone compounds
    Publication number: 20020086900
    Abstract: Methods of synthesizing pharmacologically useful oxazolidinones are disclosed, and, in particular, a method of manufacturing a 5-(tert-butylcarbamoyl)-aminomethyl-oxazolidinone by condensing a carbamate with a tert-butylcarbamoyl protected derivative of glycidylamine or 3-amino-1-halopropanol.
    Type: Application
    Filed: October 17, 2001
    Publication date: July 4, 2002
    Inventors: William R. Perrault, Robert C. Gadwood
  • Process to prepare oxazolidinones
    Patent number: 5837870
    Abstract: The present invention includes processes for producing 5-hydroxymethyl substituted oxazolidinone alcohols (III) from carbamates (IIA) or a trifluoroacetamide (IIB) using a dihydroxy compound (I) or glycidol (IV) starting material and for the transformation of the hydroxymethyl substituted oxazolidinone alcohols (III) to the corresponding amino compounds, 5-aminomethyl substituted oxazolidinone amines (VII) which are acylated to form commercially useful antibacterial 5-acylamidomethyl substituted oxazolidinone (VIII).
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: November 17, 1998
    Assignee: Pharmacia & Upjohn Company
    Inventors: Bruce A. Pearlman, William R. Perrault, Michael R. Barbachyn, Peter R. Manninen, Dana S. Toops, David J. Houser, Thomas J. Fleck