Patents by Inventor William R. Taylor

William R. Taylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETECTING CHOLANGIOCARCINOMA
    Publication number: 20250137068
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as cholangiocarcinoma.
    Type: Application
    Filed: November 21, 2024
    Publication date: May 1, 2025
    Inventors: John B. Kisiel, David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab
  • DETECTING PANCREATIC HIGH-GRADE DYSPLASIA
    Publication number: 20250137067
    Abstract: Provided herein is technology for pancreatic high-grade dysplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of pancreatic high-grade dysplasia (IPMN-HGD, PanIN-3, or PDAC).
    Type: Application
    Filed: November 11, 2024
    Publication date: May 1, 2025
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney
  • DETECTION OF COLON NEOPLASIA BY ANALYSIS OF METHYLATED DNA
    Publication number: 20250027158
    Abstract: Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.
    Type: Application
    Filed: June 17, 2024
    Publication date: January 23, 2025
    Inventors: Hatim T. Allawi, Michael W. Kaiser, Graham P. Lidgard, William R. Taylor, Tamara J. Sander, Abram M. Vaccaro
  • Detecting cholangiocarcinoma
    Patent number: 12188093
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as cholangiocarcinoma.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: January 7, 2025
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John B. Kisiel, David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab
  • DETECTING NEOPLASM
    Publication number: 20240417807
    Abstract: This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided.
    Type: Application
    Filed: June 18, 2024
    Publication date: December 19, 2024
    Inventors: William R. Taylor, Jonathan J. Harrington, Patrick S. Quint, Hongzhi Zou, Harold R. Bergen, III, David I. Smith, David A. Ahlquist
  • DIGITAL SEQUENCE ANALYSIS OF DNA METHYLATION
    Publication number: 20240368702
    Abstract: The present invention relates to methods and compositions for determination of and uses of specific methylation patterns indicative of adenoma and carcinoma. In particular, the invention relates to analysis of defined CpG loci that are coordinately methylated in DNAs from cancer and adenoma samples, methods for identifying coordinately methylated loci, and methods of using analysis of coordinately methylated loci in one or more marker regions in the design of assays for adenoma and cancer.
    Type: Application
    Filed: April 5, 2024
    Publication date: November 7, 2024
    Inventors: David A. Ahlquist, William R. Taylor, Hongzhi Zou, Graham P. Lidgard
  • Metabolically Stable HDAC Inhibitors with Trifluoromethylpyruvamide as Metal-Binding Group
    Publication number: 20240360089
    Abstract: HDAC inhibitor compounds having trifluoromethylpyruvamides or hydrates thereof, and methods of making and using the same, are described. The HDAC inhibitor compounds are useful for inhibiting HDAC activity and inhibiting growth of cancer cells.
    Type: Application
    Filed: February 23, 2024
    Publication date: October 31, 2024
    Applicant: The University of Toledo
    Inventors: Endri Karaj, Liyanaaratchige V. Tillekeratne, Riddhidev Banerjee, William R. Taylor
  • DETECTING COLORECTAL NEOPLASM
    Publication number: 20240352534
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
    Type: Application
    Filed: April 24, 2024
    Publication date: October 24, 2024
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
  • Detection of colon neoplasia by analysis of methylated DNA
    Patent number: 12049671
    Abstract: Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.
    Type: Grant
    Filed: August 23, 2021
    Date of Patent: July 30, 2024
    Assignees: Exact Sciences Corporation, Mayo Foundation for Medical Education and Research
    Inventors: Hatim T. Allawi, Michael W. Kaiser, Graham P. Lidgard, William R. Taylor, Tamara J. Sander, Abram M. Vaccaro
  • Detecting neoplasm
    Patent number: 12043871
    Abstract: This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided.
    Type: Grant
    Filed: December 6, 2022
    Date of Patent: July 23, 2024
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: William R. Taylor, Jonathan J. Harrington, Patrick S. Quint, Hongzhi Zou, Harold R. Bergen, III, David I. Smith, David A. Ahlquist
  • DETECTING GASTRIC NEOPLASM
    Publication number: 20240191308
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as gastric cancer.
    Type: Application
    Filed: November 14, 2023
    Publication date: June 13, 2024
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Hatim T. Allawi
  • DETECTING NEOPLASM
    Publication number: 20240182980
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.
    Type: Application
    Filed: October 18, 2023
    Publication date: June 6, 2024
    Inventors: David A. Ahlquist, John B. Kisiel, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
  • DETECTING OVARIAN CANCER
    Publication number: 20240182976
    Abstract: Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).
    Type: Application
    Filed: June 1, 2023
    Publication date: June 6, 2024
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Michael W. Kaiser
  • Detecting colorectal neoplasm
    Patent number: 11987847
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: May 21, 2024
    Assignees: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, EXACT SCIENCES CORPORATION
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
  • Digital sequence analysis of DNA methylation
    Patent number: 11952633
    Abstract: The present invention relates to methods and compositions for determination of and uses of specific methylation patterns indicative of adenoma and carcinoma. In particular, the invention relates to analysis of defined CpG loci that are coordinately methylated in DNAs from cancer and adenoma samples, methods for identifying coordinately methylated loci, and methods of using analysis of coordinately methylated loci in one or more marker regions in the design of assays for adenoma and cancer.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: April 9, 2024
    Assignees: Exact Sciences Corporation, Mayo Foundation for Medical Research and Education
    Inventors: David A. Ahlquist, William R. Taylor, Hongzhi Zou, Graham P. Lidgard
  • COMPOSITIONS AND METHODS FOR DETECTING GYNECOLOGICAL CANCER
    Publication number: 20240110245
    Abstract: The present disclosure relates to detecting one or more types of gynecological cancer in a biological sample from a subject. In particular, the present disclosure provides compositions and methods for detecting the presence or absence of one or more types of gynecological cancer (e.g., cervical cancer, ovarian cancer, endometrial cancer) in a biological sample from a subject having or suspected of having a gynecological cancer.
    Type: Application
    Filed: September 1, 2023
    Publication date: April 4, 2024
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney
  • DETECTING CERVICAL CANCER
    Publication number: 20240052425
    Abstract: Provided herein is technology for cervical cancer screening. In particular, provided herein are methods, compositions, and related uses for detecting the presence or absence of cervical cancer, cervical pre-cancers (e.g., cervix related in-situ adenocarcinoma, cervical intraepithelial neoplasia), and cervical cancer subtypes (e.g., cervical adenocarcinoma, squamous cell cervical cancer), or for discriminating cervical cancer from other types of gynecological cancers (e.g., endometrial, and ovarian cancers) from a biological sample (e.g., a tissue sample (e.g., cervical tissue), a blood sample, a plasma sample, a serum sample, a whole blood sample, a secretion sample (e.g., cervical secretion, vaginal secretion), an organ secretion sample, a CSF sample, a saliva sample, a urine sample, or a stool sample).
    Type: Application
    Filed: March 4, 2022
    Publication date: February 15, 2024
    Inventors: William R. Taylor, Dougias W. Mahoney, John B. Kisiel, David A. Ahlquist
  • Detecting gastric neoplasm
    Patent number: 11859254
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as gastric cancer.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: January 2, 2024
    Assignees: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Hatim T. Allawi
  • DETECTING PROSTATE CANCER
    Publication number: 20230416840
    Abstract: Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
    Type: Application
    Filed: May 24, 2023
    Publication date: December 28, 2023
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
  • Detecting neoplasm
    Patent number: 11821039
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: November 21, 2023
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, John B. Kisiel, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi