Patents by Inventor William Reade Kem

William Reade Kem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nicotine compounds and analogs thereof, synthetic methods of making compounds, and methods of use
    Patent number: 9440948
    Abstract: Embodiments of the present disclosure provide for compounds such as those shown in FIG. 1.1 (compounds A, B, C, and D), 2?substituted nicotine compounds, azetidine compounds, ether linked nicotine compounds (FIG. 1.2, compounds E, F, G, and H), methods of synthesis of the compounds, methods of treatment of a condition using compounds A, B, C, D, 2?substituted nicotine compounds, azetidine compounds, or ether linked nicotine compounds, methods of selectively stimulating alpha7 nAChR and/or alpha4beta2 receptors, and the like.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: September 13, 2016
    Assignees: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: William Reade Kem, Ferenc Soti, Anne Rouchaud, Hong Xing, Jon Lindstrom, Kristin Marie Andrud
  • Alpha7 nicotinic receptor selective ligands
    Patent number: 8592458
    Abstract: The invention relates to the design and synthesis of 3-arylidene-anabaseine compounds that exhibit enhanced selectivity toward alpha7 nicotinic receptors. The compounds are expected to be useful in treating a wide variety of conditions, including neurodegenerative conditions such as Alzheimer's Disease, neurodevelopmental diseases such as schizophrenia, and certain peripherally located inflammations mediated by macrophage infiltration.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: November 26, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: William Reade Kem, Ferenc Soti
  • NICOTINE COMPOUNDS AND ANALOGS THEREOF, SYNTHETIC METHODS OF MAKING COMPOUNDS, AND METHODS OF USE
    Publication number: 20130157995
    Abstract: Embodiments of the present disclosure provide for compounds such as those shown in FIG. 1.1 (compounds A, B, C, and D), 2?substituted nicotine compounds, azetidine compounds, ether linked nicotine compounds (FIG. 1.2, compounds E, F, G, and H), methods of synthesis of the compounds, methods of treatment of a condition using compounds A, B, C, D, 2?substituted nicotine compounds, azetidine compounds, or ether linked nicotine compounds, methods of selectively stimulating alpha7 nAChR and/or alpha4beta2 receptors, and the like.
    Type: Application
    Filed: September 2, 2011
    Publication date: June 20, 2013
    Inventors: William Reade Kem, Ferenc Soti, Anne Rouchaud, Hong Xing, Jon Lindstrom, Kristin Marie Andrud
  • CONTROLLED-RELEASE FORMULATIONS OF ANABASEINE COMPOUNDS AND USES THEREOF
    Publication number: 20120237563
    Abstract: The subject invention pertains to controlled-release dosage forms of anabaseine compounds, such as 3-(2,4-dimethoxybenzylidene)-anabaseine (also known as DMXBA or GTS-21) or a pharmaceutically acceptable salt thereof, methods of use, and methods for producing controlled-release dosage forms.
    Type: Application
    Filed: August 18, 2010
    Publication date: September 20, 2012
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC.
    Inventors: William Reade Kem, Ferenc Soti, Robert Freedman, Lynn Johnson
  • Materials and methods for inhibiting fouling of surfaces exposed to aquatic environments
    Patent number: 7307171
    Abstract: The subject invention provides materials and methods for inhibiting the biofouling of surfaces exposed to aquatic environments. In one embodiment, the subject invention provides additives for marine paints and surface treatments. The subject invention further provides repellents and selective inhibitors for aquatic and/or terrestrial crustacean pests.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: December 11, 2007
    Assignees: University of Florida, Duke University
    Inventors: William Reade Kem, Ferenc Soti, Dan Rittschof
  • Materials and methods for inhibiting fouling of surfaces exposed to aquatic environments
    Patent number: 7087106
    Abstract: The subject invention provides materials and methods for inhibiting the biofouling of surfaces exposed to aquatic environments. In one embodiment, the subject invention provides additives for marine paints and surface treatments. The subject invention further provides repellants and selective inhibitors for aquatic and/or terrestrial crustacean pests.
    Type: Grant
    Filed: February 19, 2004
    Date of Patent: August 8, 2006
    Assignees: University of Florida, Duke University
    Inventors: William Reade Kem, Ferenc Soti, Dan Rittschof
  • Materials and methods for inhibiting fouling of surfaces exposed to aquatic environments
    Publication number: 20040235901
    Abstract: The subject invention provides materials and methods for inhibiting the biofouling of surfaces exposed to aquatic environments. In one embodiment, the subject invention provides additives for marine paints and surface treatments. The subject invention further provides repellants and selective inhibitors for aquatic and/or terrestrial crustacean pests.
    Type: Application
    Filed: February 19, 2004
    Publication date: November 25, 2004
    Inventors: William Reade Kem, Ferenc Soti, Dan Rittschof