Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-3 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.

Abstract: Methods and systems are presented for making good use of recently obtained biometric data, for configuring propagule capsules (e.g. containing seeds or spores with growth media and other helpful materials) for deployment via drones so that each has an improved chance of survival, and for configuring drones or piloted craft for safe fleet deployment in remote locations.

Abstract: A computer-implemented method includes: receiving, by a computing device, information identifying the presence of a crowdsourcing event; receiving, by a computing device, indirect crowdsourcing data including user device activity from a plurality of user devices within a geofence associated with the crowdsourcing event; generating, by the computing device, indirect crowdsourcing data records based on the indirect crowdsourcing data; receiving, by the computing device, a query relating to the crowdsourcing event; generating, by the computing device, a query response in response to the query based on the indirect crowdsourcing data records; and providing by the computing device, the query response.

Abstract: A method for transitioning workflow execution includes executing, at a workstation utilizing one or more hardware processors of the workstation, a first step of a multi-step workflow; determining, utilizing a workflow engine, that a next step of the multi-step workflow is not required to be executed at a set location, and further determining that the first subsequent step of the multi-step workflow that is required to be executed at a set location is required to be executed at a server; transitioning execution of the multi-step workflow to one or more servers; and executing, at one or more servers utilizing one or more hardware processors of the one or more servers, steps of the multi-step workflow up to and including the step of the multi-step workflow that was identified as being required to be executed at a server.

Abstract: Methods and systems are presented for making good use of recently obtained biometric data, for configuring propagule capsules (e.g. containing seeds or spores with growth media and other helpful materials) for deployment via drones so that each has an improved chance of survival, and for configuring drones or piloted craft for safe fleet deployment in remote locations.

Abstract: A computer-implemented method includes: receiving, by a computing device, information identifying the presence of a crowdsourcing event; receiving, by a computing device, indirect crowdsourcing data including user device activity from a plurality of user devices within a geofence associated with the crowdsourcing event; generating, by the computing device, indirect crowdsourcing data records based on the indirect crowdsourcing data; receiving, by the computing device, a query relating to the crowdsourcing event; generating, by the computing device, a query response in response to the query based on the indirect crowdsourcing data records; and providing by the computing device, the query response.

Abstract: An embodiment of the invention provides a method for recording, managing and tracking changes to objects in a computer system. A master record is created for the computer system; and, a transactional record is created for an object in the computer system. The master record includes the current status of the object and the current status for all objects associated to the object. The transactional record is updated in the electronic database; and, the master record is updated when the transactional record is updated. The master record is linked to all of the transactional records of the objects associated to the object with the processor. The master record is updated with the processor when a transactional record of the objects associated to the object is updated or added.

Abstract: An embodiment of the invention provides a method for recording, managing and tracking changes to objects in a computer system. A master record is created for the computer system; and, a transactional record is created for an object in the computer system. The master record includes the current status of the object and the current status for all objects associated to the object. The transactional record is updated in the electronic database; and, the master record is updated when the transactional record is updated. The master record is linked to all of the transactional records of the objects associated to the object with the processor. The master record is updated with the processor when a transactional record of the objects associated to the object is updated or added.

Abstract: A polymer composite prepared by melt blending, comprising an amorphous polymer; and a crystallizable polymer; wherein upon cooling the polymer composite, the amorphous polymer forms a continuous phase and the crystallizable polymer forms a dispersed phase, and wherein the dispersed phase is less than 200 nanometers in size.

Abstract: A polyester block terpolymer comprising an amorphous block comprising a polystyrene dicarboxylate; a crystallizable block comprising a polyethylene glycol; and an aliphatic diol block; wherein the amorphous block is a continuous phase and the crystallizable block is a dispersed phase, and wherein the dispersed phase is less than about 200 nanometers in size.

Abstract: A support system for supporting a feeding tube of a person is disclosed. The support system comprises an elongated flexible band, a disc and a sling mechanism. The elongated flexible band is adapted to circumscribe the person's body, at least partially covering abdomen region of the person. The disc is disposed on the elongated flexible band and is capable of securing the feeding tube. The sling mechanism is functionally coupled to the elongated flexible band and provides support to the feeding tube, for example, while the tube is not being used to feed a user.

Abstract: A polymer composite prepared by melt blending, comprising an amorphous polymer; and a crystallizable polymer; wherein upon cooling the polymer composite, the amorphous polymer forms a continuous phase and the crystallizable polymer forms a dispersed phase, and wherein the dispersed phase is less than 200 nanometers in size.

Abstract: A polyester block terpolymer comprising an amorphous block comprising a polystyrene dicarboxylate; a crystallizable block comprising a polyethylene glycol; and an aliphatic diol block; wherein the amorphous block is a continuous phase and the crystallizable block is a dispersed phase, and wherein the dispersed phase is less than about 200 nanometers in size.

Abstract: A support system for supporting a feeding tube of a person is disclosed. The support system comprises an elongated flexible band, a disc and a sling mechanism. The elongated flexible band is adapted to circumscribe the person's body, at least partially covering abdomen region of the person. The disc is disposed on the elongated flexible band and is capable of securing the feeding tube. The sling mechanism is functionally coupled to the elongated flexible band and provides support to the feeding tube, for example, while the tube is not being used to feed a user.

Abstract: A sprinkler having a design such that they can be arrayed where the coverage of each exceeds 80 square feet—preferably less than 200 square feet in extra hazard or high piled storage environments up to ceiling heights of 25 feet or greater, including ceiling heights of approximately 30 feet or greater and being adapted to control through the maintenance of the heat release rate for the prescribed period of time established by NFPA-13 standards for what are termed “Extra Hazard” and “High Piled Storage” occupancy in which sprinklers preferably having a K factor of 18-40 through the selective combination of pressure and trigger-speed provide sufficiently large drops of water to permit the same to maintain sufficient size and density after contacting the structural members generally encountered in warehouse-type facilities to be able to penetrate the fire plume.

Abstract: A valve for fire suppression sprinkler systems is disclosed. The valve has a chamber with an inlet and an outlet. A closure member, positioned within the chamber, is movable to close and open the inlet. A latch engages the closure member to hold it in the closed position. The latch also engages a deformable diaphragm. The diaphragm deforms in response to pressure applied to it and allows the latch to move between a latched position engaged with the closure member and an unlatched position away from the closure member. When the diaphragm is depressurized it allows the latch to move and disengage from the closure member, which opens under fluid pressure from the inlet and allows fluid to flow through the valve.

Abstract: A fire suppression system is disclosed. The system includes a source of pressurized gas and a source of pressurized liquid. At least one emitter is in fluid communication with the liquid and gas sources. The emitter is used to establish a gas stream, atomize and entrain the liquid into the gas stream and discharge the resulting liquid-gas stream onto the fire. A method of operating the system is also disclosed. The method includes establishing a gas stream having first and second shock fronts using the emitter, atomizing and entraining the liquid with the gas at one of the two shock fronts to form a liquid-gas stream, and discharging the stream onto the fire. The method also includes creating a plurality of shock diamonds in the liquid-gas stream discharged from the emitter.

Abstract: An emitter for atomizing and discharging a liquid entrained in a gas stream is disclosed. The emitter has a nozzle with an outlet facing a deflector surface. The nozzle discharges a gas jet against the deflector surface. The emitter has a duct with an exit orifice adjacent to the nozzle outlet. Liquid is discharged from the orifice and is entrained in the gas jet where it is atomized. A method of operating the emitter is also disclosed. The method includes establishing a first shock front between the outlet and the deflector surface, a second shock front proximate to the deflector surface, and a plurality of shock diamonds in a liquid-gas stream discharged from the emitter.

Abstract: Polycarbonates containing low or undetectable levels of Fries rearrangement products and comprising repeat units derived from one or more of resorcinol, hydroquinone, methylhydroquinone, bisphenol A, and 4,4?-biphenol have been prepared by the melt reaction of one or more of the aforementioned dihydroxy aromatic compounds with an ester-substituted diaryl carbonate such as bis-methyl salicyl carbonate. Low, or in many instances undetectable, levels of Fries rearrangement products are found in the product polycarbonates obtained as the combined result of a highly effective catalyst system which suppresses the Fries reaction and the use of lower melt polymerization temperatures relative to temperatures required for the analogous polymerization reactions using diphenyl carbonate.

Abstract: A valve is disclosed having an inlet duct aligned with an outlet duct and an angularly oriented elliptical seat positioned between them. A pressure chamber faces the seat. A pivoting valve closure member is positioned between the pressure chamber and the seat. An asymmetrical rolling diaphragm is attached to the closure member and defines part of the pressure chamber. A seat engaging surface on the side of the closure member opposite the pressure chamber is sealingly engageable with the seat to close the valve. The valve closure member is pivoted into the closed positioned by pressurizing the pressure chamber. The valve remains closed against hydraulic pressure in the inlet duct. The valve is permitted to open by de-pressurizing the pressure chamber, allowing the closure member to pivot out of engagement with the seat. Fluid may then flow from the inlet duct to the outlet duct.