Abstract: An electrotransport device for delivering one or more therapeutic agents through the skin includes electrodes for contacting the skin, at least one electrode containing the agent, a power source for generating electrical current (IL) for delivering the agent, a current generating and controlling means and a disabling means for permanently and irreversibly disabling the current. The disabling means may include a timer means, a counter means, or a body parameter sensor and limit comparator to effect permanent disabling. The disabling means may be a permanent transition to a disabled logic state, a permanent discharge of a power supply source, or a permanent diversion of electrotransport current from the electrodes, or a combination of the above.

Abstract: A method and system for detecting a position of a metallic object are disclosed. The method includes (a) exciting a coil with an electrical signal to produce an electromagnetic field enveloping the object, (b) allowing a frequency of the electrical signal to be at the resonant frequency of the coil as affected by the object, and (c) adjusting a control signal controlling a characteristic of the electrical signal so that the characteristic substantially equals a predetermined standard level. The method further includes (d) periodically coupling and decoupling a resistive element in parallel with the coil while performing (a)-(c), and (e) deriving a signal based upon the control signal. The derived signal is indicative of a difference between first and second values of an intermediate signal functionally related to the control signal, which are obtained when the resistive element is coupled in parallel with the coil and decoupled, respectively.

Abstract: A cardiac mapping and pacing system includes a cardiac catheter having multiple electrodes and further includes an electrophysiological biological recorder. An interface system coupled between the multiple electrodes and the biological recorder permits the biological recorder to receive, process and display data acquired from the electrodes even though the number of electrodes may exceed the number of available inputs to the biological recorder. An application specific integrated circuit (ASIC) implemented as a CMOS switching circuit matrix is used to effectively interface a number of individual electrodes with a variety of existing and custom biological recorders.

Abstract: A cardiac mapping and pacing system includes a cardiac catheter having multiple electrodes and further includes an electrophysiological biological recorder. An interface system coupled between the multiple electrodes and the biological recorder permits the biological recorder to receive, process and display data acquired from the electrodes even though the number of electrodes may exceed the number of available inputs to the biological recorder. An application specific integrated circuit (ASIC) implemented as a CMOS switching circuit matrix is used to effectively interface a number of individual electrodes with a variety of existing and custom biological recorders.

Abstract: A system is used in association with a structure which, in use, is deployed in an interior body region. The structure includes an operative element. A switch matrix is coupled to the operative element. The switch matrix includes a plurality of inputs and a plurality of outputs. A controller is coupled to the switch matrix to control the switch matrix to couple the operative element to selected ones of the inputs and selected ones of the outputs in accordance with applied commands. An interface is coupled to the controller. The interface includes an input element to receive operator input and a processor to generate applied commands to the controller in response to operator input. The interface also includes an image controller to generate an image of the structure while coupled to the switch matrix. The image controller generates markers on the image in response to signals transmitted from the operative element through the switch matrix.