Abstract: A method to detect local antibodies such as antigen-specific IgE via a brush biopsy specimen of a mucosal surface of a subject is disclosed. The method is easily performed in an office setting on both adult and pediatric patients. Also disclosed is a brush device specially designed for harvesting materials from a mucosal surface such as the medial surface of the inferior turbinate.

Abstract: A nasal spray delivery guide including a pair of guide elements spaced apart from one another and configured to be at least partially inserted into respective nostrils of a patient, and a flexible connector element attached to and extending between the guide elements. Each guide element includes an aperture extending therethrough from a base end to a tip end of the guide element. A method for delivering a nasal spray into a patient's nose includes the steps of providing the nasal spray delivery guide, inserting the guide elements at least partially into respective nostrils of the patient, inserting at least a portion of a nasal spray delivery device into one of the guide elements, and activating the nasal spray delivery device to deliver a nasal spray to a lateral wall of the respective nasal cavity.

Abstract: A method to detect local antibodies such as antigen-specific IgE via a brush biopsy specimen of a mucosal surface of a subject is disclosed. The method is easily performed in an office setting on both adult and pediatric patients. Also disclosed is a brush device specially designed for harvesting materials from a mucosal surface such as the medial surface of the inferior turbinate.

Abstract: A method to detect local antibodies such as antigen-specific IgE via a brush biopsy specimen of a mucosal surface of a subject is disclosed. The method is easily performed in an office setting on both adult and pediatric patients. Also disclosed is a brush device specially designed for harvesting materials from a mucosal surface such as the medial surface of the inferior turbinate.

Abstract: Disclosed herein are kits, devices and methods for promoting, supporting and enhancing olfactory function. The kits of the present disclosure relate to devices for stimulating olfactory function that include odorous pods selected from a group of odors or more than one group of odors, whereby each odorous pod is located in a compartment of a receptacle that can be used to promote, support and enhance an individual's olfactory function. The kits of the present disclosure can also include instructional methods for using such devices to promote, support and enhance olfactory function, diagnosing or evaluating olfactory function in a subject or treating and improving olfactory function in a subject.

Abstract: A nasal spray delivery guide including a pair of guide elements spaced apart from one another and configured to be at least partially inserted into respective nostrils of a patient, and a flexible connector element attached to and extending between the guide elements. Each guide element includes an aperture extending therethrough from a base end to a tip end of the guide element. A method for delivering a nasal spray into a patient's nose includes the steps of providing the nasal spray delivery guide, inserting the guide elements at least partially into respective nostrils of the patient, inserting at least a portion of a nasal spray delivery device into one of the guide elements, and activating the nasal spray delivery device to deliver a nasal spray to a lateral wall of the respective nasal cavity.

Abstract: A method to detect local antibodies such as antigen-specific IgE via a brush biopsy specimen of a mucosal surface of a subject is disclosed. The method is easily performed in an office setting on both adult and pediatric patients. Also disclosed is a brush device specially designed for harvesting materials from a mucosal surface such as the medial surface of the inferior turbinate.

Abstract: A method to detect local antibodies such as antigen-specific IgE via a brush biopsy specimen of a mucosal surface of a subject is disclosed. The method is easily performed in an office setting on both adult and pediatric patients. Also disclosed is a brush device specially designed for harvesting materials from a mucosal surface such as the medial surface of the inferior turbinate.

Abstract: A method to detect local antibodies such as antigen-specific IgE via a brush biopsy specimen of a mucosal surface of a subject is disclosed. The method is easily performed in an office setting on both adult and pediatric patients. Also disclosed is a brush device specially designed for harvesting materials from a mucosal surface such as the medial surface of the inferior turbinate.