Patents by Inventor William Rush SCAGGS

William Rush SCAGGS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KRas inhibitors
    Patent number: 12723053
    Abstract: The present invention provides compounds of the formula: wherein A, Z, G, R1, R2, and R4 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients for cancer.
    Type: Grant
    Filed: March 29, 2024
    Date of Patent: September 1, 2026
    Assignee: Eli Lilly and Company
    Inventors: Adedoyin David Abraham, Alberto Valero De La Cruz, Alicia Marcos Llorente, Alvaro Enriquez Garcia, Andrew Dilger, Deqi Guo, Desta Bume, Frederic Laurent Cordier, Gaiying Zhao, Isabel Rojo Garcia, James Robert Henry, Jason Eric Lamar, Jolie Anne Bastian, Maria Lourdes Prieto Vallejo, Mario Barberis, Matthew Patrick Baumgartner, Miguel Garzón Sanz, Pablo Garcia Losada, Ramkumar Rajamani, Richard Duane Johnston, Robert Hazlitt, Santiago Carballares Martin, Sean Aronow, Shane Michael Walls, Sonia Maria Gutierrez Sanfeliciano, Steven Andrews, Timothy Scott Kercher, Victoriano Molero Flórez, Wenceslao Lumeras Amador, William Rush Scaggs, Juan Antonio Rincon Cabezudo, Julián Priego Soler, Xiaohong Chen
  • KRAS inhibitors
    Patent number: 12691117
    Abstract: The present invention provides compounds of the formula: wherein R1, R2, R3, and R4 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients with cancer.
    Type: Grant
    Filed: September 10, 2025
    Date of Patent: July 28, 2026
    Assignee: ELI LILLY AND COMPANY
    Inventors: Sean Aronow, Mario Barberis, Alexandra Bosnidou, Desta Bume, Xiaohong Chen, Sonia Maria Gutierrez Sanfeliciano, Timothy Scott Kercher, Wenceslao Lumeras Amador, Alicia Marcos Llorente, Julian Priego Soler, Maria Lourdes Prieto Vallejo, Ramkumar Rajamani, Isabel Rojo Garcia, William Rush Scaggs, Victoriano Molero Flórez
  • KRAS INHIBITORS
    Publication number: 20260166037
    Abstract: The present invention provides compounds of the formula: wherein R1, R2, R3, and R4 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients with cancer.
    Type: Application
    Filed: September 10, 2025
    Publication date: June 18, 2026
    Inventors: Sean ARONOW, Mario BARBERIS, Alexandra BOSNIDOU, Desta BUME, Xiaohong CHEN, Sonia Maria GUTIERREZ SANFELICIANO, Timothy Scott KERCHER, Wenceslao LUMERAS AMADOR, Alicia MARCOS LLORENTE, Julian PRIEGO SOLER, Maria Lourdes PRIETO VALLEJO, Ramkumar RAJAMANI, Isabel ROJO GARCIA, William Rush SCAGGS, Victoriano MOLERO FLÓREZ
  • KRAS inhibitors
    Patent number: 12600733
    Abstract: Provided herein are compounds of the formula: wherein A, B, R1, R2, R3a, R3b, Z1, Z2, and Z3 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients with cancer.
    Type: Grant
    Filed: September 30, 2025
    Date of Patent: April 14, 2026
    Assignee: ELI LILLY AND COMPANY
    Inventors: Adedoyin David Abraham, Sean Aronow, Desta Bume, Xiaohong Chen, Sonia Maria Gutierrez Sanfeliciano, Timothy Scott Kercher, Wenceslao Lumeras Amador, Ramkumar Rajamani, Isabel Rojo Garcia, William Rush Scaggs, Shane Walls
  • KRAS INHIBITORS
    Publication number: 20260092075
    Abstract: Provided herein are compounds of the formula: wherein A, B, R1, R2, R3a, R3b, Z1, Z2, and Z3 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients with cancer.
    Type: Application
    Filed: September 30, 2025
    Publication date: April 2, 2026
    Inventors: Adedoyin David ABRAHAM, Sean ARONOW, Desta BUME, Xiaohong CHEN, Sonia Maria GUTIERREZ SANFELICIANO, Timothy Scott KERCHER, Wenceslao LUMERAS AMADOR, Ramkumar RAJAMANI, Isabel ROJO GARCIA, William Rush SCAGGS, Shane WALLS
  • KRAS INHIBITORS
    Publication number: 20240368193
    Abstract: The present invention provides compounds of the formula: wherein A, Z, G, R1, R2, and R4 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients for cancer.
    Type: Application
    Filed: March 29, 2024
    Publication date: November 7, 2024
    Inventors: Adedoyin David ABRAHAM, Alberto VALERO DE LA CRUZ, Alicia MARCOS LLORENTE, Alvaro ENRIQUEZ GARCIA, Andrew DILGER, Deqi GUO, Desta BUME, Frederic LAURENT CORDIER, Gaiying ZHAO, Isabel ROJO GARCIA, James Robert HENRY, Jason Eric LAMAR, Jolie Anne BASTIAN, Maria Lourdes PRIETO VALLEJO, Mario BARBERIS, Matthew Patrick BAUMGARTNER, Miguel GARZÓN SANZ, Pablo GARCIA LOSADA, Ramkumar RAJAMANI, Richard Duane JOHNSTON, Robert HAZLITT, Santiago CARBALLARES MARTIN, Sean ARONOW, Shane Michael WALLS, Sonia Maria GUTIERREZ SANFELICIANO, Steven ANDREWS, Timothy Scott KERCHER, Victoriano MOLERO FLÓREZ, Wenceslao LUMERAS AMADOR, William Rush SCAGGS, Juan Antonio RINCON CABEZUDO, Julián PRIEGO SOLER, Xiaohong CHEN