Abstract: A sensor system and method for analyzing a fluid contained within an environmental control system, comprising the steps of providing a system including a passage for containing a thermal change fluid; placing a sensor including a mechanical resonator in the passage; operating the resonator to have at least a portion thereof translate through the fluid; and monitoring the response of the resonator to the fluid in the passage. A preferred sensor includes a tuning fork resonator.

Abstract: A system for monitoring a fluid in an environmental control system includes a mechanical resonator positioned for contacting a thermal change fluid. In some embodiments, the mechanical resonator is positioned in a passage for containing the thermal change fluid. Suitable thermal change fluids include an R-134A refrigerant, a mineral oil, an ester lubricant or a mixture thereof; a superheated refrigerant; or an elevated pressure and elevated temperature vapor, an elevated pressure liquid, a reduced pressure liquid, a reduced pressure vapor and combinations thereof. The mechanical resonator can be a flexural resonator or a torsion resonator. In some embodiments, the mechanical resonator is a tuning fork resonator. Methods of the invention include monitoring a response of the mechanical resonator to the thermal change fluid. In some embodiments, at least a portion of the mechanical resonator is translated through the thermal change fluid and the response of the resonator to the fluid is monitored.

Abstract: The present invention provides methods for the directed differentiation of embryonic stem cells along the endodermal lineage, especially the pancreatic lineage.

Abstract: Fluid monitoring methods, systems and apparatus are disclosed. Preferred embodiments comprise one or more flexural resonator sensing elements. In preferred embodiments a sensor or a sensor subassembly is ported to multiple fluidic systems.

Abstract: A sensor system and method for analyzing a fluid contained within an environmental control system, comprising the steps of providing a system including a passage for containing a thermal change fluid; placing a sensor including a mechanical resonator in the passage; operating the resonator to have at least a portion thereof translate through the fluid; and monitoring the response of the resonator to the fluid in the passage. A preferred sensor includes a tuning fork resonator.