Abstract: A medical instrument for enhancing diagnosis and treatment comprising a handle, an ablation probe extending from the handle, a catheter extending from the handle. The catheter defines a lumen and the ablation probe is located within the lumen of the catheter. A port in fluid communication with the lumen of the catheter is configured for connection to a vacuum or fluid source, and application of a vacuum or an injection of fluid creates a consistent zone of permittivity around the ablation probe.

Abstract: A system and method for enhancing diagnosis and treatment including an extended working channel defining an elongated passageway and adapted to extend through the bronchoscope and into a luminal network, an opening operably associated with the extended working channel and in fluid communication with the luminal network, and a medical instrument configured for insertion through the extended working channel, wherein during operation, apposition of tissue on the extended working channel or medical instrument isolates at least a portion of a luminal network in which the extended working channel is inserted.

Abstract: Provided are systems, devices, and methods for planning a medical procedure. An exemplary method includes receiving image data of a patient's chest, identifying the patient's lungs in the image data, determining locations of pleural surfaces of the patient's lungs in the image data, identifying a treatment target in the patient's lungs, generating a three-dimensional (3D) model of the patient's lungs based on the image data, the 3D model showing the pleural surfaces of the patient's lungs and the treatment target, determining whether the treatment target invades the pleural surfaces, displaying a view of the 3D model for viewing by a clinician, receiving input from the clinician regarding a plan for the medical procedure, and displaying the plan for the medical procedure.

Abstract: Provided are systems, devices, and methods of planning a medical procedure. An exemplary method includes receiving image data of a patient's chest, identifying the patient's lungs in the image data, determining locations of fissures of the patient's lungs in the image data, generating a three-dimensional (3D) model of the patient's lungs based on the image data, the 3D model showing the fissures of the patient's lungs, displaying a view of the 3D model including the fissures of the patient's lungs for viewing by a clinician, receiving input from the clinician regarding a plan for the medical procedure, and displaying the plan for the medical procedure.

Abstract: Provided in accordance with the present disclosure are systems, devices, and methods useable in training for bronchoscopy and thoracic procedures. An exemplary system includes a housing unit configured to simulate the chest cavity of a patient, at least one simulated lung located within the housing unit, the at least one simulated lung including a plurality of airways, and an exterior of the at least one simulated lung being substantially sealed from the atmosphere by the housing unit, a respiratory controller configured to control inspiration and expiration of air into and out of the plurality of airways of the at least one simulated lung, and a fluid controller configured to control administration of fluids to the at least one simulated lung.

Abstract: A method and system for instilling a medium into portions of a luminal network is provided. The method includes generating a model of a luminal network based on images of the luminal network, determining a location of a treatment target in the luminal network, navigating a bronchoscope through the bronchial tree to a target, guiding a catheter through the bronchoscope, dispensing medium to the target from a distal end of the catheter, and removing a quantity of medium from the luminal network.

Abstract: Disclosed are systems, devices, and methods for planning a procedure for treatment of tissue in a patient's lungs. An exemplary method includes generating a three-dimensional (3D) model of the patient's lungs, displaying the 3D model of the patient's lungs, selecting a target location in the tissue of the patient's lungs as displayed on the 3D model, identifying a point on a pleural surface of the patient's lungs with access to the target location, determining an access path between the target location and the identified point on the pleural surface, calculating a risk of injury to intervening structures between the identified point on the pleural surface and the target location, based on the determined access path, and displaying the access path and the calculated risk of injury for the access path on the 3D model.

Abstract: Disclosed are systems, devices, and methods for planning a procedure for treatment of lung tissue. An exemplary method includes generating a three-dimensional (3D) model of the luminal network, displaying the 3D model of the luminal network, selecting a target location in the tissue adjacent to the luminal network as displayed on the 3D model, identifying a point in the luminal network which is proximate to or at the target location, determining an access path between the target location and the identified point in the luminal network, calculating a risk of injury to intervening structures between the target location and the identified point in the luminal network, based on the determined access path, and displaying the access path and the calculated risk of injury for the access path on the 3D model.

Abstract: Disclosed are systems, devices and methods for providing proximity awareness to an anatomical feature while navigating inside a patient's chest, an exemplary method including receiving image data of the patient's chest, generating a three-dimensional (3D) model of the patient's chest based on the received image data, determining a location of the anatomical feature based on the received image data and the generated 3D model, tracking a position of an electromagnetic sensor included in a tool, iteratively determining a position of the tool inside the patient's chest based on the tracked position of the electromagnetic sensor, and indicating a proximity of the tool relative to the anatomical feature, based on the determined position of the tool inside the patient's chest.

Abstract: A system for navigating to and interacting with a region of interest during a respiratory cycle is provided. The system includes an extended working channel, a computing device including a memory and at least one processor, a plurality of images stored in the memory, a display device that displays a user interface. The user interface includes at least one image of the plurality of images depicting the region of interest and a progression of the extended working channel through the airway, and a probability diagnostic and/or treatment zone defining a probable distribution of a trajectory of the tool once deployed beyond an opening of the extended working channel displayed in the at least one image. The respiratory cycle is divided into inhalation and exhalation. The user interface is configured to depict movement of the region of interest and the airways during the respiratory cycle.

Abstract: A system and method enabling the receipt of image data of a patient, identification of one or more locations within the image data illustrating the effects of COPD, planning a pathway to the one or more locations, navigating an extended working channel to one of the locations, positioning a catheter proximate the location, and temporarily evacuating air from within a portion of a patient's lungs including the identified location illustrating the effects of COPD to temporarily isolate the portion of the lungs including the one or more actual locations.

Abstract: A method of registering an area of interest luminal network to images of the area of interest luminal network comprising. The method includes generating a model of the area of interest based on images of the area of interest, determining a location of a soft point in the area of interest, tracking a location of the location sensor while the location sensor is navigated within the area of interest, comparing the tracked locations of the location sensor within the area of interest , navigating the location sensor to the soft point, confirming the location sensor is located at the soft point, and updating the registration of the model with the area of interest based on the tracked locations of the location sensor at the soft point.

Abstract: A surgical system including an endoscopic navigation catheter, at least one laparoscopic access port, a laparoscopic tool, and an endoscopic tool. The endoscopic navigation catheter is configured for navigation of a luminal network to an area of interest. The at least one laparoscopic access port is placed adjacent to the area of interest. The laparoscopic tool is configured for insertion through the at least one laparoscopic access port, and the endoscopic tool is configured for insertion through the endoscopic navigation catheter. The laparoscopic tool and endoscopic tool enable a combined laparoscopic and endoscopic approach to the area of interest.

Abstract: A method for assessing suture line integrity includes loading a navigation plan into a navigation system, the navigation plan including a planned pathway shown in a 3D model, inserting a probe into a patient's airways, the probe including a location sensor in operative communication with the navigation system, registering a sensed location of the probe with the planned pathway, and selecting a target in the navigation plan, the target including a proposed suture line. The method further includes presenting a view of the 3D model showing the planned pathway and indicating the sensed location of the probe, navigating the probe through the airways of the patient's lungs toward the target, and imaging the proposed suture line of the target, via the probe, to determine tissue integrity surrounding the proposed suture line.

Abstract: A system and method for navigating to a target site in a patient is provided. The system includes an extended working channel and a tool usable with an electromagnetic navigation system. In particular, the extended working channel and the tool contain an electromagnetic sensor configured to provide location information within a patient of the extended working channel and the tool to the electromagnetic navigation system. The distance from the tool and the target site can then be determined and displayed to a clinician on a display device.

Abstract: Disclosed are systems, devices, and methods for performing treatment along a lumen network, an exemplary method comprising receiving image data of a patient's lungs, mapping one or more luminal networks inside the patient's lungs based on the received image data, identifying a treatment target in the image data, determining a luminal pathway to the treatment target via at least one of the luminal networks, configuring treatment parameters for treatment of the treatment target and at least one of the luminal networks, navigating a tool inside at least one of the luminal networks to the treatment target, treating the treatment target with a primary treatment modality, and treating the luminal pathway of at least one of the luminal networks leading to or from the treatment target with a secondary treatment modality.

Abstract: A system and method enabling the receipt of image data of a patient, identification of one or more locations within the image data depicting symptoms of lung disease, analyzing airways and vasculature proximate the identified locations, planning a pathway to the one or more locations, navigating an extended working channel to one of the locations, identifying the direction of blood flow within vasculature serving the location, positioning a catheter proximate the location, and temporarily isolating a portion of the identified vasculature serving the location depicting symptoms of lung disease.

Abstract: Methods for marking the location of and/or providing for an access point on a tissue wall include navigating an extended working channel (EWC) to an access point and piercing a tissue wall by piercing tool at the access point to create an opening through which the EWC may pass. The opening allows for the deployment of one or more of a diagnostic, imaging, or therapeutic modality from the EWC. Following removal of the one or more diagnostic, imaging, or therapeutic modality, a coagulant may be deposited to permit the opening to close. The location of the piercing is marked to easily identify the location at which the tissue wall was pierced for subsequent procedures.

Abstract: A surgical system includes a bronchoscope, an extended working channel defining an elongated passageway and adapted to extend through the bronchoscope, and a valve in fluid communication with the passageway of the extended working channel. The surgical system further includes an elongated surgical instrument configured and dimensioned to be inserted through the extended working channel. During operation, a fluid is able to flow from the valve and through the extended working channel such that the fluid travels within an annular area surrounding the elongated surgical instrument positioned within the extended working channel.

Abstract: A diaphragm assist device (DAD) for assistance with diaphragm contraction to facilitate breathing. The device assists with respiration of patients having diaphragmatic dysfunction including those awaiting lung transplants, and those in need of weaning from mechanical ventilation, as well as those who can benefit from an implantable ventilator.