Patents by Inventor William S. Micka

William S. Micka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dominant negative variants of methionine aminopeptidase 2 (MetAP2) and clinical uses thereof
    Publication number: 20020182701
    Abstract: Inhibitors of type 2 methionine aminopeptidases (“MetAP2”), specifically dominant negative variants of MetAP2, both polypeptides and encoding polynucleotides, are provided. Also provided are methods of treating subjects suffering from cancer, diseases mediated by the immune system or opportunistic infections using inhibitors of MetAP2. Also provided are high through put screens and assays to detect and identify inhibitors of MetAP2 and downstream effectors of MetAP2.
    Type: Application
    Filed: August 30, 2001
    Publication date: December 5, 2002
    Applicant: Saint Louis University
    Inventors: Yie-Hwa Chang, William S. Micka, Joseph A. Vetro