Patents by Inventor William Shakespeare

William Shakespeare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic heteroaryl compounds
    Publication number: 20070191376
    Abstract: This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
    Type: Application
    Filed: December 22, 2006
    Publication date: August 16, 2007
    Inventors: Dong Zou, Wei-Sheng Huang, R. Thomas, Jan Romero, Jiwei Qi, Yihan Wang, Xiaotian Zhu, William Shakespeare, Rajeswari Sundaramoorthi, Chester Metcalf,, David Dalgarno, Tomi Sawyer
  • Novel perines
    Publication number: 20050096298
    Abstract: Novel purines and uses of these compounds for the treatment of bone related disorders and cancer is disclosed.
    Type: Application
    Filed: November 22, 2004
    Publication date: May 5, 2005
    Inventors: Chester Metcalf, Manfred Weigele, Tomi Sawyer, Regine Bohacek, William Shakespeare, Rajeswari Sundaramoorthi, Yihan Wang, David Dalgarno
  • Substituted purine derivatives
    Publication number: 20050065171
    Abstract: This invention relates to compounds of the general formula: in which Y, RA, RC and R6 are as defined herein, and to their preparation and use.
    Type: Application
    Filed: June 24, 2004
    Publication date: March 24, 2005
    Inventors: William Shakespeare, Chester Metcalf, Tomi Sawyer, Yihan Wang, Rajeswari Sundaramoorthi, David Dalgarno, Regine Bohacek, Manfred Weigele
  • Amidine derivatives as inhibitors of nitric oxide synthase
    Patent number: 6489322
    Abstract: There are provided novel compounds of formula (I) wherein R1 represents a 2-thienyl or 3-thienyl ring and R2 represents hydrogen or C 1 to 4 alkyl and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are selective inhibitors of the neuronal isoform of nitric oxide synthase.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: December 3, 2002
    Assignee: AstraZeneca AB
    Inventors: James Macdonald, James Matz, William Shakespeare
  • Compounds
    Patent number: 6166030
    Abstract: There are provided novel compounds of formula (I) ##STR1## wherein R.sup.1 represents a 2-thienyl or 3-thienyl ring and R.sup.2 represents C 1 to 4 alkyl and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are selective inhibitors of the neuronal isoform of nitric oxide synthase.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: December 26, 2000
    Assignee: Astra Aktiebolag
    Inventors: James MacDonald, James Matz, William Shakespeare
  • Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase
    Patent number: 6140322
    Abstract: There are provided novel compounds of formula (I) ##STR1## wherein X, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are as defined in the specification and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy.
    Type: Grant
    Filed: January 20, 1999
    Date of Patent: October 31, 2000
    Assignee: Astra Aktiebolag
    Inventors: James MacDonald, James Matz, William Shakespeare
  • Amidine and isothiourea derivatives, compositions containing them and their use as inhibitors of nitric oxide synthase
    Patent number: 5929085
    Abstract: There are provided novel compounds of formula (I) ##STR1## wherein X, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are as defined in the specification and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy.
    Type: Grant
    Filed: January 22, 1997
    Date of Patent: July 27, 1999
    Assignee: Astra Aktiebolag
    Inventors: James MacDonald, James Matz, William Shakespeare