Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-3 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.

Abstract: An adapter probe configured for injecting fluid (e.g., liquid, gas) into at least one electrical cable. Particularly for injecting an electrical cable with a fluid when the electrical cable is affixed to a separable connector (e.g., elbow separable connector). Separable connector may be configured to connect sources of energy (e.g., transformer, circuit breaker) with distribution systems via electrical cable (or cable section).

Abstract: An adapter probe configured for injecting fluid (e.g., liquid, gas) into at least one electrical cable. Particularly for injecting an electrical cable with a fluid when the electrical cable is affixed to a separable connector (e.g., elbow separable connector). Separable connector may be configured to connect sources of energy (e.g., transformer, circuit breaker) with distribution systems via electrical cable (or cable section).

Abstract: An adapter probe configured for injecting fluid (e.g., liquid, gas) into at least one electrical cable. Particularly for injecting an electrical cable with a fluid when the electrical cable is affixed to a separable connector (e.g., elbow separable connector). Separable connector may be configured to connect sources of energy (e.g., transformer, circuit breaker) with distribution systems via electrical cable (or cable section).

Abstract: Disclosed herein are diagnostic assays using surface enhanced Raman spectroscopy (SERS)-active particles, including liquid-based assays; magnetic capture assays; microparticle-nanoparticle satellite structures for signal amplification in an assay; composite SERS-active particles useful for enhanced detection of targets; and sample tubes and processes for using the same.

Abstract: Techniques for machine learning (ML) model knowledge distillation and automatic retraining are described. A model adaptation controller obtains samples generated by an edge device and inference values generated based on the samples by a deployed ML model of the edge device. The model adaptation controller runs inference on the samples using a different ML model to generate inferences that can be used to determine whether the performance of the deployed ML model is lacking. If so, the model adaptation controller can retrain the deployed ML model using samples with ground truth values generated by the different ML model, resulting in a light-weight retrained model that can be provisioned to the edge device. This retraining process may be performed iteratively to automatically improve and adapt the ML model running at the edge device.

Abstract: A method for reducing a time-to-first-print in an imaging device that includes tracking a set of sleep times between print jobs in an imaging device and determining whether a predetermined number of sleep times in the set of sleep times is reached; and upon a positive determination, identifying a first and a second most recent sleep times stored among the set of sleep times tracked; determining whether each of the first sleep time and the second sleep time is less than a predetermined threshold; and upon a positive determination, determining a value based on an average of the first sleep time and the second sleep time. The value is used as a period of time that the imaging device is powered at a snooze mode prior to transitioning to a sleep mode, and when a print job is received in the imaging device while in the snooze mode, the time-to-first-print from the snooze mode is faster than the time-to-first print when the print job is received while in the sleep mode.

Abstract: Disclosed herein are diagnostic assays using surface enhanced Raman spectroscopy (SERS)-active particles, including liquid-based assays; magnetic capture assays; microparticle-nanoparticle satellite structures for signal amplification in an assay; composite SERS-active particles useful for enhanced detection of targets; and sample tubes and processes for using the same.

Abstract: In accordance with an embodiment, described herein is a system and method for supporting namespaces in a multitenant application server environment. The application server environment can include a domain with a plurality of partitions. A global namespace or JNDI tree bound to domain-level resources can maintain a collection of partition root nodes, with each partition root node being the root node of a partition JNDI tree. Each node in a partition JNDI tree is made partition-aware by including properties specific to a particular partition. An initial context for a partition can be created for use in dispatching resource lookup requests to the partition, and can be reused by other applications in accessing resources in the partition.

Abstract: In accordance with an embodiment, described herein is a system and method for supporting namespaces in a multitenant application server environment. The application server environment can include a domain with a plurality of partitions. A global namespace or JNDI tree bound to domain-level resources can maintain a collection of partition root nodes, with each partition root node being the root node of a partition JNDI tree. Each node in a partition JNDI tree is made partition-aware by including properties specific to a particular partition. An initial context for a partition can be created for use in dispatching resource lookup requests to the partition, and can be reused by other applications in accessing resources in the partition.

Abstract: A method for associating a customer accessible supply item of a first type with an imaging apparatus includes communicating identification information between the customer accessible supply item of the first type and the imaging apparatus; and operationally locking the customer accessible supply item of the first type with only the imaging apparatus based on the identification information, to the exclusion of other imaging apparatuses and other customer accessible supply items of the first type.

Abstract: A method for associating a customer accessible supply item of a first type with an imaging apparatus includes communicating identification information between the customer accessible supply item of the first type and the imaging apparatus; and operationally locking the customer accessible supply item of the first type with only the imaging apparatus based on the identification information, to the exclusion of other imaging apparatuses and other customer accessible supply items of the first type.

Abstract: A document printed marking including a first information marking including first luminescent taggants having a first luminescence wavelength band; and a second information marking printed at least partially on the first information marking at an overlap location. The second information marking includes second different luminescent taggant having a second different luminescence wavelength band. The second luminescence wavelength band is spaced from the first luminescence wavelength band such that the first information marking and the second information marking are substantially luminescently non-intrusive with each other at the overlap location.

Abstract: A method, apparatus, and system for providing a standard, generic contract between an application server and a message provider which allows the message provider to deliver messages to message endpoints (each of which is associated with a corresponding message application) residing in the application server is disclosed. By generic, it is meant that the contract is independent of the specific messaging style, messaging semantics and messaging infrastructure used to deliver messages. In this way, the contract also serves as the standard message provider pluggability contract that allows any message provider to be plugged into any application server via an associated resource adapter.

Abstract: A system and method for automating the transfer of real estate. A centralized server or servers are connected to a distributed computer network that is connected between a plurality of client computers. A real estate record is created on the centralized server and information is received on the server from a plurality of sources including real estate databases, computer input devices, facsimile equipment, and electronic mail systems. The centralized server is integrated with a multiple listing service wherein information can be automatically exchanged therebetween. Fax or email communications may include documents for storage on the server. The fax or email sender enters a record identifier wherein the server recognizes the record identifier and determines whether it matches an existing real estate record. If so, the server converts the document to digital form if necessary and saves it to the matching real estate record.

Abstract: Methods, software, and apparatus for transparently pairing data with a command object, with respect to the application which wishes to present the data, are disclosed. In one aspect of the present invention, a computer-implemented framework for associating data with a command object includes a data handler mechanism arranged to interface with an application which wishes to use the data. The framework also includes a data retriever mechanism that is arranged to obtain the data, and is in communication with the data handler mechanism, as well as a mapping mechanism, which is also in communication with the data handler mechanism, and is arranged to obtain the command object. In one embodiment of the present invention, the data is a stream of bytes, and the data handler mechanism is used to bind the stream of bytes to the command object.

Abstract: A method of storing usage information in an ink jet printer includes storing low priority usage information in a first memory field. First high priority usage information is stored in a second memory field. Second high priority usage information is stored in a third memory field. The second high priority usage information is substantially identical to the first high priority usage information.

Abstract: A method, apparatus, and system for providing a standard, generic contract between an application server and a message provider which allows the message provider to deliver messages to message endpoints (each of which is associated with a corresponding message application) residing in the application server is disclosed. By generic, it is meant that the contract is independent of the specific messaging style, messaging semantics and messaging infrastructure used to deliver messages. In this way, the contract also serves as the standard message provider pluggability contract that allows any message provider to be plugged into any application server via an associated resource adapter.

Abstract: A method, apparatus and system arranged to provide a connection(s) from an application component to a shared resource only as needed. In this way the total number of connections are limited to only those connections required to execute a particular method thereby saving valuable computing resources. In the described embodiment, after an invoked application component has started a particular transaction, a pre-enlistment notification is returned to the application server thereby putting all resource adapters on notice that a connection may be forthcoming.

Abstract: A method of storing usage information in an ink jet printer includes storing low priority usage information in a first memory field. First high priority usage information is stored in a second memory field. Second high priority usage information is stored in a third memory field. The second high priority usage information is substantially identical to the first high priority usage information.