Patents by Inventor William Sheffler

William Sheffler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240038331
    Abstract: Synthetic nanostructures, proteins that are useful, for example, in making synthetic nanostructures, and methods for designing such synthetic nanostructures are disclosed herein.
    Type: Application
    Filed: September 1, 2023
    Publication date: February 1, 2024
    Inventors: David BAKER, Neil KING, Jacob BALE, William SHEFFLER
  • Publication number: 20230287402
    Abstract: The disclosure provides two-dimensional protein structures including first and second polypeptides that are different, each form homo-oligomers, and interact to form a rigid interface, polypeptide components of such two-dimensional protein structures, and uses thereof.
    Type: Application
    Filed: August 23, 2021
    Publication date: September 14, 2023
    Inventors: Ariel Ben SASSON, David BAKER, William SHEFFLER, Hannele RUOHOLA-BAKER, Logeshwaran SOMASUNDARM, Emmanuel DERIVERY, Joseph WATSON
  • Publication number: 20190341124
    Abstract: Synthetic nanostructures, proteins that are useful, for example, in making synthetic nanostructures, and methods for designing such synthetic nanostructures are disclosed herein.
    Type: Application
    Filed: February 8, 2019
    Publication date: November 7, 2019
    Inventors: David BAKER, Neil KING, Jacob BALE, William SHEFFLER
  • Patent number: 10248758
    Abstract: Synthetic nanostructures, proteins that are useful, for example, in making synthetic nanostructures, and methods for designing such synthetic nanostructures are disclosed herein.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: April 2, 2019
    Assignee: University of Washington Through its Center for Commercialization
    Inventors: David Baker, Neil King, Jacob Bale, William Sheffler
  • Publication number: 20150356240
    Abstract: Synthetic nanostructures, proteins that are useful, for example, in making synthetic nanostructures, and methods for designing such synthetic nanostructures are disclosed herein.
    Type: Application
    Filed: February 7, 2014
    Publication date: December 10, 2015
    Applicant: University of Washington Through It's Center For Commercialization
    Inventors: David BAKER, Neil KING, Jacob BALE, William SHEFFLER
  • Patent number: 8969521
    Abstract: Methods and systems for computationally designing self-assembling polypeptides are disclosed. A representation of a docked configuration of a symmetric protein architecture can be determined by a computing device configured to computationally symmetrically dock representations of protein building blocks within a representation of a symmetric protein architecture, where symmetrically docking a representation of a particular protein building block can include determining a configuration of the protein building blocks in three-dimensional space within the symmetric protein architecture configured to generate interfaces between building blocks suitable for computational protein interface design. The amino acid sequence of the docked protein building blocks can be computationally modified to specify protein-protein interfaces between the plurality of protein building blocks that are energetically favorable to drive self-assembly of a protein that includes the modified amino acid sequence.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: March 3, 2015
    Assignee: University of Washington Through its Center for Commercialization
    Inventors: David Baker, Neil King, William Sheffler, Todd Yeates
  • Publication number: 20130274441
    Abstract: Methods and systems for computationally designing self-assembling polypeptides are disclosed. A representation of a docked configuration of a symmetric protein architecture can be determined by a computing device configured to computationally symmetrically dock representations of protein building blocks within a representation of a symmetric protein architecture, where symmetrically docking a representation of a particular protein building block can include determining a configuration of the protein building blocks in three-dimensional space within the symmetric protein architecture configured to generate interfaces between building blocks suitable for computational protein interface design. The amino acid sequence of the docked protein building blocks can be computationally modified to specify protein-protein interfaces between the plurality of protein building blocks that are energetically favorable to drive self-assembly of a protein that includes the modified amino acid sequence.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 17, 2013
    Applicants: The Regents of the University of California, University of Washington through its Center for Commercialization
    Inventors: David Baker, Neil King, William Sheffler, Todd Yeates
  • Publication number: 20050030310
    Abstract: A graphical user interface for a computer system includes a display portion configured to display a representation of a first three-dimensional object, wherein the first three-dimensional object has an associated first volume, and a control icon associated with the first three-dimensional object, wherein the control icon is configured to allow a user to specify a bend amount to the first three-dimensional object in a first dimension, wherein the display portion is also configured to display a representation of a bent first three-dimensional object, wherein the bent first three-dimensional object comprises the first three-dimensional object that is bent lengthwise in response to the bend amount, and that may have an adjusted thickness in response to the bend amount.
    Type: Application
    Filed: May 6, 2004
    Publication date: February 10, 2005
    Applicant: Pixar
    Inventors: Steven Hunter, David Mullins, Robert Russ, William Wise, William Sheffler, Christian Hoffman
  • Publication number: 20050007370
    Abstract: A graphical user interface for a computer system includes a display portion configured to display a representation of a first three-dimensional object and a second three-dimensional object, wherein the first three-dimensional object has an associated first volume, and wherein the second three-dimensional object has an associated second volume, and a control icon associated with the first three-dimensional object, wherein a user can specify a modification to the first three-dimensional object in a first dimension via the control icon, wherein the display portion is also configured to display a representation of a modified first three-dimensional object, wherein the modified first three-dimensional object comprises the first three-dimensional object that is modified in the first dimension in response to the modification and that is modified in a second dimension in response to the modification and to a volume preservation value.
    Type: Application
    Filed: January 27, 2004
    Publication date: January 13, 2005
    Applicant: Pixar
    Inventors: Steven Hunter, David Mullins, Robert Russ, William Wise, William Sheffler, Christian Hoffman
  • Patent number: 6169881
    Abstract: A method (1300) and apparatus (300) combines a terminal blockage profile for a ground-to-satellite terminal with satellite location and motion data for one or more satellites (12) in a satellite communication system (10) to predict an impending service outage or impairment on a real-time or near real-time basis and reports such impending outages or impairments, and the expected duration thereof, to the terminal operator. The prediction of an impending outage or impairment also can include analysis of information concerning atmospheric conditions in the vicinity of the terminal location as well as other potential sources of a service outage or impairment.
    Type: Grant
    Filed: May 4, 1998
    Date of Patent: January 2, 2001
    Assignee: Motorola, Inc.
    Inventors: Richard Lawrence Astrom, Brian Michael Daniel, Alvin William Sheffler