Patents by Inventor William Shingler

William Shingler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunotherapeutic method
    Patent number: 8642274
    Abstract: The present invention provides a method of monitoring the efficacy of an immunotherapy in a mammalian subject, wherein the subject has been administered an immunotherapy, wherein the immunotherapy comprises a viral vector containing a polynucleotide encoding an antigen, wherein the viral vector is capable of transducing cells in the mammalian subject to cause the cells to express the antigen; the method comprising: (b) measuring, from a biological sample isolated from the subject, an immune response of the subject to the antigen and comparing the immune response of the subject to the antigen to a reference measurement of immune response to the antigen; (c) measuring, from a biological sample isolated from the subject, an immune response of the subject to the viral vector and comparing the immune response of the subject to the viral vector to a reference measurement of immune response to the viral vector; and (d) determining efficacy based on the comparisons of (b) and (c), wherein an elevated immune response
    Type: Grant
    Filed: July 15, 2009
    Date of Patent: February 4, 2014
    Assignee: Oxford Biomedica, Inc.
    Inventors: Richard Harrop, William Shingler, Stuart Naylor, Michael McDonald
  • CHEMO-IMMUNOTHERAPY METHOD
    Publication number: 20120213822
    Abstract: A method of treating or preventing disease, said method comprising administering to a subject, simultaneously, sequentially or separately, an antigen and a chemotherapeutic agent or agents comprising the steps of: administering the chemotherapeutic agent or agents, and administering an antigen up to 6 weeks after the chemotherapeutic agent.
    Type: Application
    Filed: February 21, 2012
    Publication date: August 23, 2012
    Applicant: OXFORD BIOMEDICA (UK) LIMITED
    Inventors: Richard Harrop, Michelle Kelleher, William Shingler, Susan Mary Kingsman, Miles William Carroll
  • Peptide
    Patent number: 8147838
    Abstract: The present invention relates to peptide epitopes of 5T4 antigen and their use in immunotherapy. In particular, the present invention relates to any one of the peptide epitopes as described herein as well as their used in diagnosis and therapy of cancer.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: April 3, 2012
    Assignee: Oxford Biomedica (UK) Limited
    Inventors: Richard Harrop, William Shingler, Susan Mary Kingsman
  • Chemo-immunotherapy method
    Patent number: 8133681
    Abstract: A method of treating or preventing disease, said method comprising administering to a subject, simultaneously, sequentially or separately, an antigen and a chemotherapeutic agent or agents comprising the steps of: administering the chemotherapeutic agent or agents, and administering an antigen up to 6 weeks after the chemotherapeutic agent.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: March 13, 2012
    Assignee: Oxford Biomedica (UK) Limited
    Inventors: Richard Harrop, Michelle Kelleher, William Shingler, Susan Mary Kingsman, Miles William Carroll
  • IMMUNOTHERAPEUTIC METHOD
    Publication number: 20100124534
    Abstract: The present invention provides a method of monitoring the efficacy of an immunotherapy in a mammalian subject, wherein the subject has been administered an immunotherapy, wherein the immunotherapy comprises a viral vector containing a polynucleotide encoding an antigen, wherein the viral vector is capable of transducing cells in the mammalian subject to cause the cells to express the antigen; the method comprising: (b) measuring, from a biological sample isolated from the subject, an immune response of the subject to the antigen and comparing the immune response of the subject to the antigen to a reference measurement of immune response to the antigen; (c) measuring, from a biological sample isolated from the subject, an immune response of the subject to the viral vector and comparing the immune response of the subject to the viral vector to a reference measurement of immune response to the viral vector; and (d) determining efficacy based on the comparisons of (b) and (c), wherein an elevated immune response
    Type: Application
    Filed: July 15, 2009
    Publication date: May 20, 2010
    Applicant: OXFORD BIOMEDICA (UK) LIMITED
    Inventors: Richard Harrop, William Shingler, Stuart Naylor, Michael McDonald
  • PEPTIDE
    Publication number: 20090280138
    Abstract: The present invention relates to peptide epitopes of 5T4 antigen and their use in immunotherapy. In particular, the present invention relates to any one of the peptide epitopes as described herein as well as their use in diagnosis and therapy of cancer.
    Type: Application
    Filed: May 12, 2006
    Publication date: November 12, 2009
    Applicant: OXFORD BIOMEDICA (UK) LIMITED
    Inventors: Richard Harrop, William Shingler, Susan Kingsman
  • Chemo-Immunotherapy Method
    Publication number: 20090047307
    Abstract: A method of treating or preventing disease, said method comprising administering to a subject, simultaneously, sequentially or separately, an antigen and a chemotherapeutic agent or agents comprising the steps of: administering the chemotherapeutic agent or agents, and administering an antigen up to 6 weeks after the chemotherapeutic agent.
    Type: Application
    Filed: March 20, 2008
    Publication date: February 19, 2009
    Applicant: OXFORD BIOMEDICA (UK) LIMITED
    Inventors: Richard Harrop, Michelle Kelleher, William Shingler, Susan Mary Kingsman, Miles William Carroll