Abstract: A method of disinfecting using a light diffusing fiber includes optically coupling a light source to a light diffusing optical fiber having a core, a cladding surrounding the core, an outer surface, and a plurality of scattering structures positioned within the core, the cladding, or both the core and the cladding. The method further includes positioning the light diffusing optical fiber in optical engagement with a pathogen sample and directing light output by the light source into the light diffusing optical fiber for a first time interval. The scattering structures scatter light propagating along the light diffusing optical fiber toward the outer surface and a portion of the light diffuses through the outer surface thereby irradiating the pathogen sample with light having an average power density of about 5 mW/cm2 to about 30 mW/cm2 at a wavelength from about 380 nm to about 495 nm for an exposure time from about 2 hours to about 24 hours.

Abstract: A system includes: an acoustic exciter; a compliant material applied to the acoustic exciter to configure the acoustic exciter for triggering acoustic excitation of at least part of a substrate; a sensor configured to receive an acoustic response of the acoustic excitation; and circuitry configured to determine at least one characteristic of the substrate using the acoustic response.

Abstract: Systems and methods for optimizing outcomes in multi-factor systems are described. Business process management, consulting intelligence, business intelligence, mobile intelligence, artificial intelligence, machine learning, and transportation management are integrated, as discussed herein, for optimizing transportation and logistics processes. Users may input legacy knowledge and data such as text, numbers, formulas, algorithms, and automated processes into a computing system for providing the system with industry insights for intelligently analyzing situation contexts, or the system may leverage third-party data. The system may suggest recommended actions based on analyzed situation contexts, and the system may furthermore execute various actions for responding to the situation contexts. The system may be configured to automatically analyze situation contexts and furthermore automatically execute various actions for responding to the situation contexts.

Abstract: A system or platform with architecture for dynamically orchestrating secure data flows across components in a healthcare enterprise, including, but not limited to, medical devices, electronic health records, clinical decision support systems, patient administration systems, and the like. The present invention enables plug-and-play interoperability via standards-based, trusted, bi-directional communication between components. The system provides dynamic registration of components and their profiles, runtime provisioning of communications channels, and dynamic orchestration of data between components. Component profiles abstract devices and applications as services producing and consuming certain messages that represent portions of a canonical data model. Registration takes a component identity and assigns an identifier and address to broker communication with the component.

Abstract: Systems and methods for optimizing outcomes in multi-factor systems are described. Business process management, consulting intelligence, business intelligence, mobile intelligence, artificial intelligence, machine learning, and transportation management are integrated, as discussed herein, for optimizing transportation and logistics processes. Users may input legacy knowledge and data such as text, numbers, formulas, algorithms, and automated processes into a computing system for providing the system with industry insights for intelligently analyzing situation contexts, or the system may leverage third-party data. The system may suggest recommended actions based on analyzed situation contexts, and the system may furthermore execute various actions for responding to the situation contexts. The system may be configured to automatically analyze situation contexts and furthermore automatically execute various actions for responding to the situation contexts.

Abstract: The present invention provides a training device for training a user to use a pressurised metered dose inhaler (PMDI). The device comprises a body, air expulsion means (e.g. bellows) for expelling air along an air flow path and an actuator for actuation of the air expulsion means. The air flow path comprises a restriction such that upon expulsion of air along the air flow path, an audible signal is generated. The audible signal mimics that generated during use of a PMDI.

Abstract: A product bag includes a bladder and an elongated filtration device. The bladder includes opposing first and second film layers defining a product chamber. The first and second film layers are sealed together along a perimeter seal extending along at least a portion of a perimeter of the bladder. The elongated filtration device includes a housing, a filtration membrane disposed in the housing, an inlet adapted for receiving a fluid to be filtered, and an outlet in fluid communication with the product chamber. A majority of the elongated filtration device is embedded between the first and second film layers of the perimeter seal of the bladder to provide for a compact form factor.

Abstract: A sterile solution product bag for lyophilizing includes a bladder, a first stem having a first stem inlet end and a first stem outlet end. The first stem outlet end is fluidly connected to the bladder and the first stem inlet end is adapted to receive a liquid. A first filter is disposed in-line with the first stem and includes a first filter membrane, a first filter open end, and a first filter closed end. The first filter closed end is disposed between the first stem inlet end and the first stem outlet end and the first filter open end is disposed in proximity to the first stem inlet end. A second stem having a second stem inlet end fluidly connected to the bladder and a second stem outlet end adapted to receive a vapor. A second filter is disposed within the second stem and includes a filter membrane.

Abstract: A system for disinfecting a medical device is provided. The system includes a light source that generates light having at least one wavelength between about 100 nm and about 500 nm. The system further includes at least one cylindrical optical diffuser disposed in optical communication with at least one interior channel of a medical device, the at least one cylindrical optical diffuser having an outer surface and an end optically coupled to the light source. The at least one cylindrical optical diffuser is configured to scatter guided light through the outer surface to form a light diffuser portion having a length that emits substantially uniform radiation over its length.

Abstract: A therapeutic illumination assembly includes a catheter and a point source treatment fiber. The catheter comprises a catheter wall encircling a luminal fluid pathway. The point source treatment fiber is positioned within the luminal fluid pathway of the catheter. Further, the point source treatment fiber comprises a plurality of light emitting point sources intermittently positioned along a treatment length of the point source treatment fiber such that the plurality of light emitting point sources irradiate the catheter when the plurality of light emitting point sources emit light.

Abstract: Digital content such as eBooks, music, video, personal files, and so forth stored in cloud storage resources are selectively transferred to an onboard storage device of a conveyance such as an aircraft, train, motorcoach, and so forth. Travelers may access the content from the onboard storage as if the cloud were still accessible.

Abstract: An illumination system for a surgical device is provided. The illumination system includes a tubular body made of a light permeable material and having at least one lumen extending between a distal end and a proximal end. The illumination system further includes a light source. At least one light diffusing optical fiber is disposed in the at least one lumen, the at least one light diffusing optical fiber having a core, primary cladding, and a plurality of nano-sized structures, the optical fiber further including an outer surface, and an end optically coupled to the light source. The fiber is configured to scatter guided light via the nano-sized structures away from the core and through the outer surface, to form a light-source fiber portion having a length that emits substantially uniform radiation over its length.

Abstract: Systems and methods for optimizing outcomes in multi-factor systems are described. Business process management, consulting intelligence, business intelligence, mobile intelligence, artificial intelligence, machine learning, and transportation management are integrated, as discussed herein, for optimizing transportation and logistics processes. Users may input legacy knowledge and data such as text, numbers, formulas, algorithms, and automated processes into a computing system for providing the system with industry insights for intelligently analyzing situation contexts, or the system may leverage third-party data. The system may suggest recommended actions based on analyzed situation contexts, and the system may furthermore execute various actions for responding to the situation contexts. The system may be configured to automatically analyze situation contexts and furthermore automatically execute various actions for responding to the situation contexts.

Abstract: A system and method for autonomous sustenance of digital assets, including but not limited to digital media, is described. The system may include one or more smart contracts which provide terms for executing a provision of a digital asset to a user on a permanent or duration limited basis. The method may include ensuring the terms of the smart contract are executed such that digital rights holders in the digital assets are paid for access to the digital asset.

Abstract: A therapeutic illumination assembly includes a catheter and a point source treatment fiber. The catheter comprises a catheter wall encircling a luminal fluid pathway. The point source treatment fiber is positioned within the luminal fluid pathway of the catheter. Further, the point source treatment fiber comprises a plurality of light emitting point sources intermittently positioned along a treatment length of the point source treatment fiber such that the plurality of light emitting point sources irradiate the catheter when the plurality of light emitting point sources emit light.

Abstract: A system for disinfecting a medical device is provided. The system includes a light source that generates light having at least one wavelength between about 100 nm and about 500 nm. The system further includes at least one cylindrical optical diffuser disposed in optical communication with at least one interior channel of a medical device, the at least one cylindrical optical diffuser having an outer surface and an end optically coupled to the light source. The at least one cylindrical optical diffuser is configured to scatter guided light through the outer surface to form a light diffuser portion having a length that emits substantially uniform radiation over its length.

Abstract: This disclosure describes architectures and techniques to provide information to a user about items with which the user interacts. In some instances, a user may utilize a wearable device that is configured to interact with one or more components of an information discovery system to obtain information about items in the user's environment.

Abstract: A system and method host an electronic marketplace in which the initial product prices are set by the selling party and the final purchase price is determined by the time between product posting and payment from a buyer. Gamification is implemented using purchasable powerups to allow users to manipulate the prices during a product listing. The seller has two options for the increment or decrement rate of the price of the product: automatic or manual. In the automatic incrementation, the system increments or decrements the final price by cross-referencing the time and the product seller's inputted choice of UP or DOWN at the time of posting. In the manual incrementation, the seller selects the speed in which the price is increased or decreased from the start to the end of the product listing based on the seller's inputted choice of UP or DOWN at the time of posting.

Abstract: A method of mixing a pharmaceutical solution including adding a gas into an interior compartment of a mix bag to form a headspace. The interior compartment of the mix bag includes a top portion and a bottom portion. The headspace adjacent to the top portion contains gas. The method includes adding a solvent into the mix bag, and establishing a bubble column in the interior compartment by activating a recirculation assembly. The recirculation assembly includes a connecting pathway operably coupled to a recirculation pump. A first end of the connecting pathway is coupled to a top gas recirculation port and a second end is coupled to a bottom gas recirculation port of the mix bag such that the recirculation pump draws the gas from the headspace and delivers the gas to the interior compartment via the bottom gas recirculation port. The method includes adding a solute into the mix bag.

Abstract: An architecture includes a system to create an augmented reality environment in which images are projected onto a scene and user movement within the scene is captured. The augmented reality environment is hosted within a surrounding area in which various ambient conditions, external to the augmented reality environment, persist. The architecture monitors the external conditions and controls secondary devices that selectively modify the conditions as desired in cooperation with operation of the augmented reality environment to effectively enhance user experience. Alternatively or additionally, the architecture may inform the user of what changes to make, and the user manually makes the adjustments.