Abstract: A clamping device for holding beehive honeycomb frames within the rotating reels of a centrifuge. The clamp includes a pair of parallel bars biased apart by spring pins and held at one end by a hinge pin connected to a holding bracket which is affixed to the inside face of the centrifuge reel. The other end of the spring-loaded parallel bars snaps into bosses mounted on a second holding bracket affixed to the opposite inside face of the centrifuge reel. To remove the clamp, the user extends his hand across the spring-loaded bars and tightens his grip to compress the bars together so that one end of the bars will disengage the bosses. The user then pivots the whole clamp about the hinge pin so that the frames can be removed.