Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.

Abstract: Disclosed herein are compositions including an aptamer bound to a complex, wherein the complex comprises at least two polypeptides. Also disclosed are methods of quantifying a fraction of PD1 occupied by PDL1 or a fraction of PDL1 occupied by PD1 in a sample, and methods of isolating complexes using aptamers that are capable of binding to the complex.

Abstract: Disclosed herein are compositions including an aptamer bound to a complex, wherein the complex comprises at least two polypeptides. Accordingly, methods of using the aptamers and making the aptamers are also disclosed.

Abstract: Disclosed herein are compositions including an aptamer bound to a complex, wherein the complex comprises at least two polypeptides. Accordingly, methods of using the aptamers and making the aptamers are also disclosed.

Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.

Abstract: Adjustable stool are configured to provide comfort and support for an occupant in a plurality of environments, including environments having uneven surfaces, such as a yard. Adjustable stools may include a seat platform and a pair of arms. The seat platform configured to support the occupant may comprise a seating surface and a plurality of pins. The plurality of pins may be affixed to corners of the seat platform and extend away from the seat platform. The pair of arms may define a slotted portion, with the slotted portion comprising a plurality of endpoints. The slotted portion may be configured to be engaged by each of the plurality of pins that extend away from the seat platform. Each of the plurality of pins may be configured to be reversibly held at each of the plurality of endpoints, with each of the plurality of endpoints defining a height of the adjustable stool. The plurality of endpoints may comprise a pattern.

Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.

Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.

Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.

Abstract: The present invention relates to optimized HER2 aptamers and methods of using these aptamers.

Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.

Abstract: A multifunctional cart is disclosed. The multifunctional cart has a frame and a pair of arms, with the arms extending outward from the frame, and a plurality of platform support members attached to the pair of arms at spaced distances outward from the frame. A platform is slideably engageable between platform support members, providing a height adjustable surface.

Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.

Abstract: The present invention relates to optimized HER2 aptamers and methods of using these aptamers.

Abstract: An airfoil for a gas turbine engine is provided that includes a first sidewall and a second sidewall coupled together at a leading edge and a trailing edge, such that a cavity is defined therebetween. A central plenum and an impingement chamber are defined within the cavity. The central plenum channels cooling fluid to the impingement chamber where cooling fluid impinges on the sidewalls. Cooling fluid is discharged from the impingement chamber via film cooling holes.

Abstract: A system includes a solid state persistent storage device, and a plurality of storage controllers to manage access of the solid state persistent storage device. An expander circuit is connected to the solid state persistent storage device and has a plurality of computer-based bus interfaces connected to the corresponding plurality of storage controllers.

Abstract: A system includes a solid state persistent storage device, and a plurality of storage controllers to manage access of the solid state persistent storage device. An expander circuit is connected to the solid state persistent storage device and has a plurality of computer-based bus interfaces connected to the corresponding plurality of storage controllers.

Abstract: The present invention is a painting accessory which is adapted to hold a wet paintbrush, holds touch-up paint, attaches to a standard sized paint bucket, attaches to a standard sized roller tray, or may be hand-held. It includes an inner curved surface and an outer curved surface which straddle a side of a standard sized paint bucket, securely attaching to the paint bucket. It includes a lid which seals the wet paintbrush and touch-up paint so that one may stop painting for a short period of time, and resume without the necessity of cleaning the brushes and pouring the paint back into the paint bucket. It reduces the amount of drying that would otherwise occur.

Abstract: Disclosed is a method and apparatus for accessing data in a computer system after a failed data operation in which I/O process state information is unknown. The failed data operation may cause data inconsistency among multiple devices associated with a shadow set for storing data. The disclosed system includes techniques for allowing continued data accesses while simultaneously re-establishing data consistency among members of the shadow set.