Patents by Inventor William Thiel
William Thiel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210180067Abstract: Disclosed herein are compositions including an aptamer bound to a complex, wherein the complex comprises at least two polypeptides. Also disclosed are methods of quantifying a fraction of PD1 occupied by PDL1 or a fraction of PDL1 occupied by PD1 in a sample, and methods of isolating complexes using aptamers that are capable of binding to the complex.Type: ApplicationFiled: February 1, 2021Publication date: June 17, 2021Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATIONInventors: George Weiner, William Thiel, Paloma Giangrande, Suresh Veeramani, Sue Blackwell
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Patent number: 10934549Abstract: Disclosed herein are compositions including an aptamer bound to a complex, wherein the complex comprises at least two polypeptides. Accordingly, methods of using the aptamers and making the aptamers are also disclosed.Type: GrantFiled: August 20, 2018Date of Patent: March 2, 2021Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATIONInventors: George Weiner, William Thiel, Paloma Giangrande, Suresh Veeramani, Sue Blackwell
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Publication number: 20190136240Abstract: Disclosed herein are compositions including an aptamer bound to a complex, wherein the complex comprises at least two polypeptides. Accordingly, methods of using the aptamers and making the aptamers are also disclosed.Type: ApplicationFiled: August 20, 2018Publication date: May 9, 2019Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATIONInventors: George Weiner, William Thiel, Paloma Giangrande, Suresh Veeramani, Sue Blackwell
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Patent number: 10113172Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.Type: GrantFiled: April 17, 2017Date of Patent: October 30, 2018Assignee: University of Iowa Research FoundationInventors: Paloma Giangrande, Francis Miller, William Thiel
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Patent number: 9949566Abstract: Adjustable stool are configured to provide comfort and support for an occupant in a plurality of environments, including environments having uneven surfaces, such as a yard. Adjustable stools may include a seat platform and a pair of arms. The seat platform configured to support the occupant may comprise a seating surface and a plurality of pins. The plurality of pins may be affixed to corners of the seat platform and extend away from the seat platform. The pair of arms may define a slotted portion, with the slotted portion comprising a plurality of endpoints. The slotted portion may be configured to be engaged by each of the plurality of pins that extend away from the seat platform. Each of the plurality of pins may be configured to be reversibly held at each of the plurality of endpoints, with each of the plurality of endpoints defining a height of the adjustable stool. The plurality of endpoints may comprise a pattern.Type: GrantFiled: July 4, 2017Date of Patent: April 24, 2018Inventor: Frank William Thiel, III
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Publication number: 20170226512Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.Type: ApplicationFiled: April 17, 2017Publication date: August 10, 2017Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATIONInventors: Paloma Giangrande, Francis Miller, William Thiel
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Patent number: 9624497Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.Type: GrantFiled: August 18, 2015Date of Patent: April 18, 2017Assignee: University of Iowa Research FoundationInventors: Paloma Giangrande, Francis Miller, William Thiel
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Publication number: 20160108403Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.Type: ApplicationFiled: August 18, 2015Publication date: April 21, 2016Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATIONInventors: Paloma Giangrande, Francis Miller, William Thiel
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Patent number: 9163242Abstract: The present invention relates to optimized HER2 aptamers and methods of using these aptamers.Type: GrantFiled: April 27, 2011Date of Patent: October 20, 2015Assignee: University of Iowa Research FoundationInventors: Paloma H. Giangrande, James O. McNamara, Kristina W. Thiel, William Thiel, William M. Rockey
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Patent number: 9139835Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.Type: GrantFiled: August 12, 2013Date of Patent: September 22, 2015Assignee: University of Iowa Research FoundationInventors: Paloma Giangrande, Francis Miller, William Thiel
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Publication number: 20150225006Abstract: A multifunctional cart is disclosed. The multifunctional cart has a frame and a pair of arms, with the arms extending outward from the frame, and a plurality of platform support members attached to the pair of arms at spaced distances outward from the frame. A platform is slideably engageable between platform support members, providing a height adjustable surface.Type: ApplicationFiled: April 27, 2015Publication date: August 13, 2015Inventor: Frank William THIEL
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Publication number: 20140056959Abstract: The present invention relates to optimized aptamers and methods of using these aptamers.Type: ApplicationFiled: August 12, 2013Publication date: February 27, 2014Applicant: University of Iowa Research FoundationInventors: Paloma Giangrande, Francis Miller, William Thiel
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Publication number: 20130129719Abstract: The present invention relates to optimized HER2 aptamers and methods of using these aptamers.Type: ApplicationFiled: April 27, 2011Publication date: May 23, 2013Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATIONInventors: Paloma H. Giangrande, James O. McNamara, Kristina W. Thiel, William Thiel, William M. Rockey
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Publication number: 20130104567Abstract: An airfoil for a gas turbine engine is provided that includes a first sidewall and a second sidewall coupled together at a leading edge and a trailing edge, such that a cavity is defined therebetween. A central plenum and an impingement chamber are defined within the cavity. The central plenum channels cooling fluid to the impingement chamber where cooling fluid impinges on the sidewalls. Cooling fluid is discharged from the impingement chamber via film cooling holes.Type: ApplicationFiled: October 31, 2011Publication date: May 2, 2013Inventors: Douglas Gerard Konitzer, Mark Willard Marusko, James Herbert Deines, Brian David Przeslawski, MIchael William Bell, Andrew David William Thiel, Xi Yang
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Patent number: 8020035Abstract: A system includes a solid state persistent storage device, and a plurality of storage controllers to manage access of the solid state persistent storage device. An expander circuit is connected to the solid state persistent storage device and has a plurality of computer-based bus interfaces connected to the corresponding plurality of storage controllers.Type: GrantFiled: September 30, 2008Date of Patent: September 13, 2011Assignee: Hewlett-Packard Development Company, L.P.Inventors: Douglas L. Voigt, David William Thiel, David Alan Daigle
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Publication number: 20100083040Abstract: A system includes a solid state persistent storage device, and a plurality of storage controllers to manage access of the solid state persistent storage device. An expander circuit is connected to the solid state persistent storage device and has a plurality of computer-based bus interfaces connected to the corresponding plurality of storage controllers.Type: ApplicationFiled: September 30, 2008Publication date: April 1, 2010Inventors: Douglas L. Voigt, David William Thiel, David Alan Daigle
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Publication number: 20070018066Abstract: The present invention is a painting accessory which is adapted to hold a wet paintbrush, holds touch-up paint, attaches to a standard sized paint bucket, attaches to a standard sized roller tray, or may be hand-held. It includes an inner curved surface and an outer curved surface which straddle a side of a standard sized paint bucket, securely attaching to the paint bucket. It includes a lid which seals the wet paintbrush and touch-up paint so that one may stop painting for a short period of time, and resume without the necessity of cleaning the brushes and pouring the paint back into the paint bucket. It reduces the amount of drying that would otherwise occur.Type: ApplicationFiled: July 10, 2006Publication date: January 25, 2007Inventor: William Thiel
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Patent number: 6192460Abstract: Disclosed is a method and apparatus for accessing data in a computer system after a failed data operation in which I/O process state information is unknown. The failed data operation may cause data inconsistency among multiple devices associated with a shadow set for storing data. The disclosed system includes techniques for allowing continued data accesses while simultaneously re-establishing data consistency among members of the shadow set.Type: GrantFiled: December 16, 1997Date of Patent: February 20, 2001Assignee: Compaq Computer CorporationInventors: William Lyle Goleman, Scott Howard Davis, David William Thiel
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Patent number: 4107763Abstract: A kit for adapting a flame-producing lamp to electrical use by mounting on the lamp a fiber optic bundle having a portion shaped to simulate a flame and a lamp for illuminating that bundle at a position remote from its shaped portion.Type: GrantFiled: November 26, 1976Date of Patent: August 15, 1978Assignee: Rank Precision Industries, Inc.Inventors: William A. Thiel, Harry Dziedzic
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Patent number: D884372Type: GrantFiled: August 23, 2018Date of Patent: May 19, 2020Inventor: Frank William Thiel, III