Abstract: A rail car mover attachment includes a remote removably mounted in a machine cab and including an emergency actuator to abruptly activate a rail car brake, a lock pin actuator to move a lock pin relative to a rail car latch in a rail car coupler, and/or a controlled stop actuator to selectively activate a rail car brake. The attachment can include an onboard compressor, such as a high volume compressor. The attachment can include a disconnect unit that self-activates rail car brakes if the attachment loses power or detaches from equipment. The attachment can include a light showing the attachment is charged and running or showing a fault. The attachment can include a laterally extending indicator arm deployable when the rail car coupler is fully attached to the rail car, and that extends beyond a rail car width so that a spotter can visually verify the coupler status. A related method of use also is provided.

Abstract: A system may include sensors that may acquire health data related to an individual. The system may also include a processor that may receive trip data associated with a current location of the individual and a destination location for the individual, traffic condition data associated with routes between the current location and the destination location, and weather related data associated with the routes. The processor may also receive the health data from the sensors and determine whether the individual is associated with a driver assessment score above a threshold based on the trip data, the traffic condition data, the weather data, the health data, or any combination thereof. The processor may then send an activation signal to a vehicle control system in response to the driver assessment score being above the threshold, such that the activation signal may enable the vehicle control system to control operations of a vehicle.

Abstract: A method includes obtaining data indicating an amount of energy stored by a battery of a sensor device; receiving data related to at least one condition in an area in which the sensor device is located; determining a reporting interval based on the data indicating the amount of energy stored by the battery of the sensor device and the data related to at least one condition in the area in which the sensor device is located; transmitting data indicating the reporting interval to the sensor device; and receiving a plurality of measurement reports transmitted from the sensor device according to the reporting interval. The energy consumed by the sensor device can be dynamically modified by dynamically modifying the reporting interval.

Abstract: The present disclosure provides compositions and methods that employ the compositions for conducting pairwise sequencing and for generating concatemer template molecules for pairwise sequencing. The concatemers can be generated using a rolling circle amplification reaction which is conducted either on-support, or conducted in-solution and then distributed onto a support. The rolling circle amplification reaction generates concatemers containing tandem copies of a sequence of interest and at least one universal adaptor sequence. An increase in the number of tandem copies in a given concatemer increases the number of sites along the concatemer for hybridizing to multiple sequencing primers which serve as multiple initiation sites for polymerase-catalyzed sequencing reactions. When the sequencing reaction employs detectably labeled nucleotides and/or detectably labeled multivalent molecules (e.g.

Abstract: Provided are a system and method of generating an aggregated stability map of one or more rotational sources associated with a heart rhythm disorder. In accordance therewith, a plurality of rotational area profile maps is accessed for a plurality of analysis intervals. Each of the profile maps includes rotation intensity values for a plurality of locations associated with rotation of the one or more rotational sources. An aggregated stability map is generated based on the profile maps, wherein the stability map includes a plurality of locations. Each location includes a rotation intensity value based at least on a filter number of highest rotation intensity values from corresponding locations of the profile maps, the filter number being automatically determined from a plurality of filter numbers such that the plurality of profile maps as filtered includes a predetermined number of rotation intensity values in excess of a threshold intensity value.

Abstract: Methods and systems are provided that are directed to automatically adjusting a user interface based on tilt position of a digital drawing board. The digital drawing board has a tiltable screen with a sensor. The tiltable screen may be fixed in a stable tilt position. A sensor is used to determine that the digital drawing board has a first tilt position. The digital drawing board displays a first user interface associated with the first tilt position. The first user interface may be associated with a first use mode. The first user interface may also be based on an application running on the digital drawing board. When the sensor senses that the digital drawing board has moved from the first tilt position to a second tilt position, it automatically displays a second user interface associated with a second tilt position. The second user interface has different functionality than the first user interface.

Abstract: The present invention relates to variant Fc-containing molecules, such as antibodies and Fc-fusion molecules, having glycosylation characteristics favorable to largescale production of therapeutic molecules containing such variant Fc. Described herein are compositions and methods to improve glycosylation maturation of and to minimize the culture process-dependent effects of Fc-containing molecules, e.g., Fc-fusion molecules and antibodies. Creating single and multiple amino acid substitutions within the Fc domain with the aim to improve high mannose processing and glycosylation maturation.

Abstract: An external support that routes the tubing of a reversing valve in such a manner that connection tubes extend from one end of the device and the treatment device tubes extend from the opposite end. The external support may provide guides that hold the tubing extending from the supported flat rotary switch type of valve so as to keep them from being pinch or kinked thereby ensuring free flow of blood.

Abstract: Systems and methods for managing non-associative communications between devices is provided. A first call chain that indicates a routing between phone numbers is stored. A first phone call or a first SMS text is received from a first session initiation protocol (SIP) provider. Based on information provided by the first SIP provider, (i) a sender identity of the first phone call or the first SMS text; (ii) a receiver identity of the first phone call or the first SMS text; and (iii) an access mode of the call chain are determined. If the receiver identity corresponds to a first phone number in the first call chain, a second phone call or a second SMS text is initiated via a second SIP provider, from a second phone number in the first call chain, based on the sender identity and the access mode.

Abstract: A well plate assembly with an interior channel system in the well plate lid provides a more efficient and uniform distribution of fluid into a receptacle positioned below the well plate lid. The channel system in the lid allows air, or other fluid, to pass through with the use of a pump to each of a plurality of channels in the receptacle. Inlet and outlet valves in the lid prevent a gasket positioned between the lid and the receptacle from releasing contact with the receptacle due to high pressure experienced during the injection of fluid into the assembly. Specifically, pressure under a specified tolerance passes through the inlet valves, and if the pressure within the channel system exceeds the limit of the outlet valve, the outlet valve opens and allows air to escape the lid safely without disturbing the fluid flow into the channels below.

Abstract: A computer-implemented method and system for workload scheduling based on localizing virtual computing resources. The computer implemented method includes, in one embodiment, localizing a first computing resource having a workload under execution, the first computing resource being associated with a set of virtual computing resources. An embodiment includes rescheduling, responsive to the localizing, the workload for execution at least partially at a second computing resource in the set of virtual computing resources.

Abstract: A method is provided of controlling a gas turbine having a shaft connecting a compressor to a turbine, as well as having a reheat system, and a gas turbine. The method includes the steps of: operating the engine using the reheat system to provide a mass flow rate of reheat fuel into a gas flow of the gas turbine engine downstream of an exit of the turbine; detecting a shaft break event in the shaft; and in response to this detection, maintaining the mass flow rate of the reheat fuel being provided into the gas flow downstream of the turbine exit, whereby the maintained mass flow rate of reheat fuel raises a back pressure downstream of the turbine and thereby reduces a rotational speed of the turbine.

Abstract: A workpiece inspection and defect detection system includes a light source, a lens that inputs image light arising from a surface of a workpiece, and a camera that receives imaging light transmitted along an imaging optical path. The system utilizes images of workpieces acquired with the camera as training images to train a defect detection portion to detect defect images that include workpieces with defects. Anomaly detector classification characteristics are determined based on features of the training images. Run mode images of workpieces are acquired with the camera, and based on determined features from the images, the anomaly detector classification characteristics are utilized to determine if the images of the workpieces are classified as anomalous. In addition, the defect detection portion determines if images are defect images that include workpieces with defects and for which additional operations may be performed (e.g., metrology operations for measuring dimensions of the defects, etc.

Abstract: A product release system, method and device that enables product controllers to generate product listings for one or more products as well as one or more customized prepurchase events for each of the products. The product release system, method and device then executes the prepurchase events according to one or more pricing, timing and permission conditions specified for each of the prepurchase events, facilitates the purchasing of the products during the prepurchase events and notifies the product controllers of the results of the prepurchase events.

Abstract: A food locker includes a housing, a food support member, a first door, a second door, and a lock. The housing includes a front wall a front wall, a rear wall, and a chamber. The front wall includes a first opening in communication with the chamber. The rear wall includes a second opening in communication with the chamber. The food support member is disposed within the chamber. The first door is supported by the housing and is movable between a closed position and an open position. The food support member is accessible through the first opening when the first door is in the open position. The second door is supported by the housing and is movable between a closed position and an open position. The food support member is accessible through the second opening when the second door is in the open position. The lock is operatively coupled to at least one of the housing and the first door and is actuatable between a locked configuration and an unlocked configuration.

Abstract: The present disclosure is drawn to material sets for 3-dimensional printing, 3-dimensional printing systems, and 3-dimensional printed parts. A material set can include a thermoplastic polymer powder having an average particle size from 20 ?m to 100 ?m, a photoluminescent ink including a photoluminescent agent, and a fusing ink. The fusing ink can include a fusing agent capable of absorbing electromagnetic radiation to produce heat.

Abstract: Systems and methods for blockchain-based secure storage are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for blockchain-based secure storage may include: (1) receiving a plurality of data files from a data file source; (2) bundling the plurality of data files into a package; (3) generating a first hash for each file name for each of the plurality of data files, and a second hash for contents of each of the plurality of data files; (4) generating a block comprising the first hash, the second hash, and a reference to a prior block; (5) encrypting each of the plurality of data files in the package; (6) sending the plurality of packages to a storage provider; and (7) committing the block to a distributed ledger.

Abstract: A device, system, and method are provided for inspecting, activating or voiding scratch-off instant lottery tickets. A remote point-of-sale device has a detector system that detects tampering with the coating placed over concealed game play information on the tickets, and reads coded identification and authentication information on the tickets. The device automatically communicates the coded identification and tampering data to a central computer system of a lottery. The central computer system provides activation signals back to the point of sale on a ticket-by-ticket basis. The device, method and system provide automated generation and communication of ticket-by-ticket tampering, activation, and voiding data between the remote device and a central computer system of a lottery.

Abstract: A spinal implant includes a first member having an inner surface defining an implant cavity and at least one mating element. A second member includes a head and a shaft configured to penetrate tissue. The head includes at least one mating element engageable with the at least one mating element of the first member and a part. A third member includes an inner surface engageable with the part such that the members comprise a bone fastener having a selected movement. Systems, instruments and methods are disclosed.