Abstract: Apparatus, systems, and methods are contemplated for electric powered vertical takeoff and landing (eVTOL) aircraft. Such are craft are engineered to carry safely carry at least 500 pounds (approx. 227 kg) using at least four, and more preferably at least six variable speed tilt rotors. In some embodiments one or more rotors cooperate to generate at least 50% of the lift, and more preferably at least 70% of the lift, during rotorborne flight (e.g., vertical takeoff, hover, etc). At least some of the blades of each of the at least four rotors are not feathered, retracted, or folded during forward flight. At least one of the variable speed tilt rotors is engineered to be optionally powered by multiple motors, and by multiple battery packs or other independently operating electric power sources. The vehicle preferably flies in an autopilot or pilotless mode and has a relatively small (e.g., less than 45? diameter) footprint.

Abstract: This disclosure provides methods of using compositions comprising amino acid entities to reduce fat infiltration in muscle, particularly under conditions of muscle atrophy. The disclosure also provides methods for enhancing muscle function by reducing fat infiltration in the muscle comprising administering an effective amount of the compositions to a subject in need thereof.

Abstract: Wearable electronic devices, such as watches, can be provided with an attachment system for connecting and releasing a removable module that interfaces with some portion of the electronic device. For example, a watch housing includes a main body having a channel for receiving a watchband and a first opening extending to the channel. A rear cover coupled to the main body provides a second opening. A unibody button is positioned between the main body and the rear cover. The button is biased against the rear cover and is moveable toward the channel to release a watchband engaged therein.

Abstract: An electrosurgical instrument includes a jaw member having an electrically conductive tissue sealing plate configured to operably couple to a source of electrosurgical energy for treating tissue. A polydimethylsiloxane coating having a thickness in the range of from about 35 nm to about 85 nm is disposed on the tissue sealing plate.

Abstract: Techniques are disclosed for casting high-strength and highly formable metal products from recycled metal scrap without the addition of substantial or any amounts of primary aluminum. Additional alloying elements, such as magnesium, can be added to metal scrap, which can be cast and processed to produce a desirable metal coil at final gauge having desirable metallurgical and mechanical properties, such as high strength and formability. Thus, inexpensive and recycled metal scrap can be efficiently repurposed for new applications, such as automotive applications and beverage can stock.

Abstract: A site-specific customizable nacelle for a wind turbine includes a plurality of walls arranged together to form an inner volume. The walls include a base wall, side walls, a front wall, a rear wall, and a top wall. Each of the walls is constructed of one or more outer skin layers positioned adjacent to one or more inner skin layers and infused together via a resin material. Further, the nacelle includes a plurality of reinforcement members secured to one or more of the plurality of walls on an interior side or an exterior side of at least one of the one or more outer skin layers or the one or more inner skin layers at locations requiring additional reinforcement. As such, the reinforcement members can be tailored according to a particular wind turbine site.

Abstract: A signal processor is configured to receive signaling containing information about a sensed sinusoidal waveform of magnetic flux caused by a current flowing in a winding of a motor having a component of distortion caused at least in part by a magnetic flux created by the current flowing, and also about a pure sinusoidal waveform of a sensed fundamental frequency of the magnetic flux; and determine corresponding signaling containing information about anomalies in the motor that depends on a relationship between the sensed sinusoidal waveform and the pure sinusoid waveform, based upon the signaling received. The signaling may be sensed and provided by a motor magnetic flux sensor attached externally to the motor frame.

Abstract: An apparatus includes a first wire and a second wire which are coupled to a right upper ankle belt and a right lower ankle belt, a third wire and a fourth wire which are coupled to a left upper ankle belt and a left lower ankle belt, an obtainer obtaining information about a road surface where a user walks, and a controller controlling tensions of the first wire and the second wire at the same time and controlling tensions of the third wire and the fourth wire at the same time using a first stiffness target value corresponding to the first wire, a second stiffness target value corresponding to the second wire, a third stiffness target value corresponding to the third wire, and a fourth stiffness target value corresponding to the fourth wire that are determined based on the information about the road surface.

Abstract: Horizontal motion conveyors for moving material and methods for reversing such horizontal motion conveyors are disclosed. In some embodiments, the horizontal motion conveyor includes a motor such as a servomotor that is connected to the driveshaft that drives the horizontal motion of the conveyor. In some embodiments, the speed profile of the pan may be changed to reverse direction of the flow of material on the pan without slowing or stopping the drive motor.

Abstract: The present invention comprises compounds of Formula I. wherein: R1, R3, R4, R5, R6, R7, R8, and Q are defined in the specification. The invention also comprises a method of treating or ameliorating a ROR-?-t mediated syndrome, disorder or disease, including wherein the syndrome, disorder or disease is selected from the group consisting of rheumatoid arthritis, psoriatic arthritis, and psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.

Abstract: A method, system and computer program product for managed object replication and delivery redirects, directly or indirectly, a client's request for an object that is not available at a best or optimal handling edge server of a network to a parent server that has the requested object. So, where the requested object is not available at the handling edge server, the client's request is redirected directly to the parent server that can provide the requested object to the client or indirectly via one or more parent servers to a parent server that can provide the requested object to the client. The method, system and computer program product further intelligently replicates the object to the edge server if the object is popular enough. Likewise, an object is removed from an edge server when it is no longer popular. All redirection and replication operations are preferably transparent to the end-user and do not degrade the quality of service.

Abstract: Apparatus and methods for delivering humidified breathing gas to a patient a provided. The apparatus includes a humidification system configured to deliver humidified breathing gas to a patient. The humidification system includes a vapor transfer unit and a base unit The vapor transfer unit includes a liquid passage, a breathing gas passage, and a vapor transfer device positioned to transfer vapor to the breathing gas passage from the liquid passage. The base unit includes a base unit that releasably engages the vapor transfer unit to enable reuse of the base unit and selective disposal of the vapor transfer unit. The liquid passage is not coupled to the base unit for liquid flow therebetween when the vapor transfer unit is received, by the base unit.

Abstract: An optimized harmonic drive (“OHD”) includes a wave generator, a flex spline, and a circular rigid spline. The wave generator includes a wave generator contour that minimizes a velocity profile of the wave generator during a high load condition. The flex spline is attached to the wave generator and the circular rigid spline is mechanically engaged to the flex spline. The flex spline includes a plurality of flex spline teeth and the circular rigid spline includes a plurality of rigid spline teeth. The plurality of rigid spline teeth is greater than the plurality of flex spline teeth and the high load condition exists when the rigid spline teeth of the plurality of rigid spline teeth are fully engaged with flex spline teeth of the plurality of flex spline teeth.

Abstract: An actuator for use in a surgical instrument, the actuator includes an upper portion configured to be actuated by one or more fingers, wherein the upper portion has an upper distal portion for operating the surgical instrument in a first mode of operation, and an upper proximal portion for operating the surgical instrument in a second mode of operation, and wherein the upper distal portion and the upper proximal portion have different respective tactile configurations for informing the user of the first and second modes of operation, respectively.

Abstract: An example technique is performed by a client on a device, and includes: obtaining attributes relating to the device, to one or more wireless networks, or to both the device and the one or more wireless networks; evaluating the attributes in voting modules of the client to generate votes, with a voting module evaluating one or more of the attributes and generating a vote; making a determination, based on the votes, to connect the device to a wireless network of the one or more wireless networks, or to maintain a connection between the device and the wireless network; and controlling the device based on the determination.

Abstract: A latch assembly for a shock strut may comprise a first linkage coupled to a strut cylinder and a shrink piston of the shock strut. A second linkage may be coupled to the strut cylinder. The second linkage may be configured to rotate the first linkage in response to the shock strut translating between a landing gear up position and a landing gear down position.

Abstract: A system may include a flow cell through which a plurality of reagents may be pumped during a genetic sequencing operation, an effluent line that, in operation, is to conduct a used reagent, a used reagent valve to receive the used reagent from the effluent line and controllable to select one of a plurality of disposal paths for the used reagent, and control circuitry coupled to the used reagent valve that, in operation, is to control the used reagent valve to select a desired one of the disposal paths depending upon which reagent is being pumped though the flow cell.