Abstract: Disclosed herein are methods of preparing a composition comprising crystalline biomolecules, for example, crystalline antibodies. In exemplary embodiments, the method comprises forming a fluidized bed of crystalline biomolecules using, for example, a counter-flow centrifuge to exchange buffer and/or to concentrate the crystalline biomolecules in a solution. Also provided are methods of detecting crystalline biomolecules and/or amorphous biomolecules in a sample.

Abstract: Disclosed herein are methods of preparing a composition comprising crystalline biomolecules, for example, crystalline antibodies. In exemplary embodiments, the method comprises forming a fluidized bed of crystalline biomolecules using, for example, a counter-flow centrifuge to exchange buffer and/or to concentrate the crystalline biomolecules in a solution. Also provided are methods of detecting crystalline biomolecules and/or amorphous biomolecules in a sample.

Abstract: A monitoring and alert system for retro-fitting to latching mechanisms. A master control unit is located proximate to an operator of the system. It includes a user interface having: an input enabling an operator to arm the system and then allow it to operate with minimal interaction of the operator. It also includes an output alerting the operator as to the status of the system in relation to a plurality of prescribed conditions. One or more slave units having sensing units detecting a latched and unlatched state are attached to a discrete latching mechanism for detecting the latching status thereof. Each slave unit comprises sensing means to detect whether the latching mechanism is in a latched state or an unlatched state.

Abstract: A monitoring and alert system for retro-fitting to latching mechanisms. A master control unit is located proximate to an operator of the system. It includes a user interface having: an input enabling an operator to arm the system and then allow it to operate with minimal interaction of the operator. It also includes an output alerting the operator as to the status of the system in relation to a plurality of prescribed conditions. One or more slave units having sensing units detecting a latched and unlatched state are attached to a discrete latching mechanism for detecting the latching status thereof. Each slave unit comprises sensing means to detect whether the latching mechanism is in a latched state or an unlatched state.