Patents by Inventor William V. Giannobile

William V. Giannobile has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of Treating Alvelor Bone Loss Through The Use of Anti-Sclerostin Antibodies
    Publication number: 20180169234
    Abstract: The invention provides a method of treating alveolar bone loss involving administration of a sclerostin inhibitor to a subject in need thereof.
    Type: Application
    Filed: January 31, 2018
    Publication date: June 21, 2018
    Inventors: Hua Zhu Ke, Min Liu, William V. Giannobile
  • Method of treating alvelor bone loss through the use of anti-sclerostin antibodies
    Patent number: 9913900
    Abstract: The invention provides a method of treating alveolar bone loss involving administration of a sclerostin inhibitor to a subject in need thereof.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: March 13, 2018
    Assignees: AMGEN INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Hua Zhu Ke, Min Liu, William V. Giannobile
  • METHOD OF TREATING ALVELOR BONE LOSS THROUGH THE USE OF ANTI-SCLEROSTIN ANTIBODIES
    Publication number: 20170281761
    Abstract: The invention provides a method of treating alveolar bone loss involving administration of a sclerostin inhibitor to a subject in need thereof.
    Type: Application
    Filed: April 21, 2017
    Publication date: October 5, 2017
    Applicants: AMGEN INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Hua Zhu Ke, Min Liu, William V. Giannobile
  • Method of treating alveolar bone loss through the use of anti-sclerostin antibodies
    Patent number: 9657090
    Abstract: The invention provides a method of treating alveolar bone loss involving administration of a sclerostin inhibitor to a subject in need thereof.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: May 23, 2017
    Assignees: AMGEN INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Hua Zhu Ke, Min Liu, William V. Giannobile
  • Multi-analyte analysis of saliva biomarkers as predictors of periodontal and pre-implant disease
    Patent number: 9002654
    Abstract: The present invention relates to methods of measuring biomarkers to determine the probability of a periodontal and/or peri-implant disease. More specifically, the invention provides a panel of biomarkers that, when used in combination, can allow determination of the probability of a periodontal and/or peri-implant disease state with extremely high accuracy.
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: April 7, 2015
    Assignees: The Regents of the University of Michigan, Sandia National Laboratories
    Inventors: Thomas Braun, William V. Giannobile, Amy E. Herr, Anup K. Singh, Charlie Shelburne
  • METHOD OF TREATING ALVEOLAR BONE LOSS THROUGH THE USE OF ANTI-SCLEROSTIN ANTIBODIES
    Publication number: 20140314776
    Abstract: The invention provides a method of treating alveolar bone loss involving administration of a sclerostin inhibitor to a subject in need thereof.
    Type: Application
    Filed: December 11, 2012
    Publication date: October 23, 2014
    Inventors: Hua Zhu Ke, Min Liu, William V. Giannobile
  • Porous objects having immobilized encapsulated biomolecules
    Patent number: 8709464
    Abstract: A porous object includes a porous material having internal pore surfaces and external pore surfaces. Releasing material encapsulated biomolecules are immobilized on at least one of the internal pore surfaces, at least one of the external pore surfaces, or combinations thereof.
    Type: Grant
    Filed: January 10, 2008
    Date of Patent: April 29, 2014
    Assignee: The Regents of the University of Michigan
    Inventors: Peter X. Ma, Guobao Wei, William V. Giannobile, Qiming Jin
  • Multi-Analyte Analysis of Saliva Biomarkers as Predictors of Periodontal and Pre-Implant Disease
    Publication number: 20100196941
    Abstract: The present invention relates to methods of measuring biomarkers to determine the probability of a periodontal and/or peri-implant disease. More specifically, the invention provides a panel of biomarkers that, when used in combination, can allow determinniation of the probability of a periodontal and/or peri-implant disease state with extremely high accuracy.
    Type: Application
    Filed: July 30, 2008
    Publication date: August 5, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Thomas Braun, William V. Giannobile, Amy E. Herr, Anup K. Singh
  • POROUS OBJECTS HAVING IMMOBILIZED ENCAPSULATED BIOMOLECULES
    Publication number: 20080317816
    Abstract: A porous object includes a porous material having internal pore surfaces and external pore surfaces. Releasing material encapsulated biomolecules are immobilized on at least one of the internal pore surfaces, at least one of the external pore surfaces, or combinations thereof.
    Type: Application
    Filed: January 10, 2008
    Publication date: December 25, 2008
    Inventors: Peter X. Ma, Guobao Wei, William V. Giannobile, Qiming Jin
  • Pyridinoline crosslinks as markers of periodontal and peri-implant disease activity
    Patent number: 5516699
    Abstract: A method of diagnosing severity of periodontal disease or peri-implant disease in a human patient, involving a) obtaining a sample of tissue or gingival crevicular or other fluid from the mouth of said patient, or a blood or urine sample from the patient, and b) measuring a pyridinoline crosslinked compound in the sample as a measure of severity of disease.
    Type: Grant
    Filed: February 16, 1994
    Date of Patent: May 14, 1996
    Assignees: Institute of Molecular Biology, Inc., President and Fellows of Harvard College
    Inventors: William V. Giannobile, Ray C. Williams, Samuel E. Lynch