Patents by Inventor William W. Turner, Jr.

William W. Turner, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic peptide antifungal agents and process for preparation thereof
    Patent number: 6384013
    Abstract: Provided are compounds of the formula (1): wherein R′ is hydrogen, methyl or NH2C(O)CH2—; R″ and R′″ are independently methyl or hydrogen; R and Ry are independently hydroxy or hydrogen; R1 is hydroxy, hydrogen, or hydroxysulfonyloxy; R7 is hydroxy, hydrogen, hydroxysulfonyloxy or phosphonooxy; R2 is a acyl side chain. Also provided are formulations, methods of inhibiting fungal and parasitic activity, and a process for preparing dideoxy (R═H) forms of the compounds.
    Type: Grant
    Filed: April 14, 1999
    Date of Patent: May 7, 2002
    Assignee: Eli Lilly and Company
    Inventors: Frederick J. Burkhardt, Manuel Debono, Jeffrey S. Nissen, William W. Turner, Jr.
  • Cyclic peptide antifungal agents
    Patent number: 5965525
    Abstract: Provided are compounds of the formula (1): ##STR1## wherein R' is hydrogen, methyl or NH.sub.2 C(O)CH.sub.2 --;R" and R'" are independently methyl or hydrogen;R and R.sup.y are independently hydroxy or hydrogen;R.sub.1 is hydroxy, hydrogen, or hydroxysulfonyloxy;R.sub.7 is hydroxy, hydrogen, hydroxysulfonyloxy or phosphonooxy;R.sub.2 is a novel acyl side chain. Also provided are novel formulations, methods of inhibiting fungal and parasitic activity, and a process for preparing dideoxy (R=H) forms of the compounds.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: October 12, 1999
    Assignee: Eli Lilly and Company
    Inventors: Frederick J. Burkhardt, Manuel Debono, Jeffrey S. Nissen, William W. Turner, Jr.
  • Cyclic peptide antifungal agents and process for preparation thereof
    Patent number: 5932543
    Abstract: Provided are compounds of the formula (1): ##STR1## wherein R' is hydrogen, methyl or NH.sub.2 C(O)CH.sub.2 --;R" and R'" are independently methyl or hydrogen;R and R.sup.Y are independently hydroxy or hydrogen;R.sub.1 is hydroxy, hydrogen, or hydroxysulfonyloxy;R.sub.7 is hydroxy, hydrogen, hydroxysulfonyloxy or phosphonooxy;R.sub.2 is a novel acyl side chain. Also provided are novel formulations, methods of inhibiting fungal and parasitic activity, and a process for preparing dideoxy (R=H) forms of the compounds.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: August 3, 1999
    Assignee: Eli Lilly and Company
    Inventors: Frederick J. Burkhardt, Manuel Debono, Jeffrey S. Nissen, William W. Turner, Jr.
  • Cyclic peptide antifungal agents and methods of making and using
    Patent number: 5786325
    Abstract: Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I ##STR1## where: R', R", R'", R.sup.x1, R.sup.x2, R.sup.y1, R.sup.y2, R.sup.y3, R.sup.y4, and R.sup.0 are as defined above; andR.sup.2 is ##STR2## each R.sup.2a is independently hydroxy, halo, nitro, amino, trifluoromethyl, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy or C.sub.1 -C.sub.6 alkylthio;a is 1, 2, 3 or 4;R.sup.3 is C.sub.1 -C.sub.12 alkyl, C.sub.1 -C.sub.12 alkoxy or --O--(CH.sub.2).sub.m --?O--(CH.sub.2).sub.n !.sub.p --O--(C.sub.1 -C.sub.12 alkyl);m is 2, 3 or 4;n is 2, 3 or 4; andp is 0 or 1;or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 11, 1996
    Date of Patent: July 28, 1998
    Assignee: Eli Lilly and Company
    Inventors: Peter S. Borromeo, William W. Turner, Jr.