Abstract: A methodology for defining resistance-capacitance (RC) design targets based on radio-frequency (RF) simulation is provided. In particular, the method may involve first determining capacitance targets and then determining resistance targets. To compute the capacitance targets, integrate circuit design and simulations tools may run transient analysis to identify critical nodes, perform small signal and sensitivity analysis for the capacitance on the critical nodes, revise original RF specifications by allocating additional margin, and perform interpolation among multiple capacitance values to obtain capacitive design targets that meet the revised specifications.