Abstract: Systems for visualization and management of a clinical study have a processor, an input device, a database storing data related to the clinical study, and a visit schedule interface. The data have a study visit schedule. The study visit schedule has nodes and a track having a step sequence. Each node has a node position and node attributes. The node position has a node track identifying the track and a node step. The data may also have a visit travel policy and the node attributes may have a visit policy label associated with the visit travel policy.

Abstract: A system for visualization and management of participants in studies having a graphical user interface (GUI), a database (DB) storing studies data, visit schedules, travel policies, sites data, and participants data having a first participant in a first study. The GUI has controls including system control, data controls (being one or more of a travel policy control, visit schedule control, and participant control), navigation control associated with the study, and selection control associated with the participant. The GUI responsive to using the controls can a) switch GUI views; b) receive and display participants data; c) receive and display visit schedule and travel policy associated with the first participant and with the first study; d) receive input data from the input device and cause the DB to update the studies data, participants data, travel policies, and visit schedules with the input data. DB may store a second participant.

Abstract: Systems for visualization and management of a study have an input device, a user interface, controls, and a database storing a visit schedule about the study and visit data about a participant. Visit schedule has a first node and second node. The participant visit data has a current visit associated with the first node. The user interface visually associates the first node with a first graphic and with a current visual attribute, and the second node with a second graphic. Responsive to the controls, the user interface associates the second node with the current visit and visually associates the current node graphic with the second node. Visit schedule may have a third node selected from a jump, cycle, exit, and other nodes. The third node is associated with an occurred visit in the visit data, and the user interface can visually associate an occurred visual attribute with the third node.

Abstract: The present invention provides a more efficient firing system and bolt kit design for a paintball marker. In an embodiment of the invention, a firing mechanism comprises a bolt and a valve that are not mechanically joined together, so the valve opens and closes independently of the bolt's position. The valve opens away from a seat or seal in the same direction of travel as the paintball. The valve is part of the control system for the bolt such that the valve is acted upon to initiate the firing sequence.

Abstract: A privacy enabled system for managing clinical study participant travel has a database (stores data: clinical study, participant, clinical site and trip data sets) and a graphical user interface that has a Travel Planning Interface and is in data communication with an input device and the database. The data sets include a Study Travel Policy, a Study Visit Schedule (appointment procedure, appointment schedule), a traveler profile, traveler personal data (traveler contact information), a site appointment location associated with the appointment procedure, and site contact information. The travel planning interface receives the trip data set (trip segment data) from the database and the input device. The travel planning interface transmits the trip segment data to and receives booked travel data from a travel booking module, generates an itinerary that has booked travel and trip segment data, and transmits the itinerary according to the traveler contact information and the site contact information.

Abstract: Systems for visualization and management of a travel policy for a clinical study have a study dataset having a first travel policy condition, a study travel policy dataset having a main travel policy and a specialized travel policy, and a GUI having a travel policies interface and a travel policy control. The first travel policy condition may be a country, a clinical site, a traveler policy label, a visit attribute, a visit policy label, and combinations thereof. The specialized travel policy (a country policy, a site policy, a first visit policy, a second visit policy, a custom policy, and combinations thereof) is programmatically associated with the first travel policy condition.

Abstract: A privacy enabled system for managing clinical study participant travel has a database (stores data: clinical study, participant, clinical site and trip data sets) and a graphical user interface that has a Travel Planning Interface and is in data communication with an input device and the database. The data sets include a Study Travel Policy, a Study Visit Schedule (appointment procedure, appointment schedule), a traveler profile, traveler personal data (traveler contact information), a site appointment location associated with the appointment procedure, and site contact information. The travel planning interface receives the trip data set (trip segment data) from the database and the input device. The travel planning interface transmits the trip segment data to and receives booked travel data from a travel booking module, generates an itinerary that has booked travel and trip segment data, and transmits the itinerary according to the traveler contact information and the site contact information.

Abstract: Systems for visualization and management of a travel policy for a clinical study have a study dataset having a first travel policy condition, a study travel policy dataset having a main travel policy and a specialized travel policy, and a GUI having a travel policies interface and a travel policy control. The first travel policy condition may be a country, a clinical site, a traveler policy label, a visit attribute, a visit policy label, and combinations thereof. The specialized travel policy (a country policy, a site policy, a first visit policy, a second visit policy, a custom policy, and combinations thereof) is programmatically associated with the first travel policy condition.

Abstract: The present invention provides a gas regulator with a diaphragm-type seal for a paintball marker or other type of gas-operated device. All regulator components are housed within a base to offer component longevity, easy adjustment of the regulated pressure, and simple maintenance. The diaphragm type seal acts as a sensing element where a seat rides on the interior surface of the diaphragm. Because the seat is positioned inside the diaphragm, a direct path is created to maintain constant pressure and increase accuracy from the seat to a pin valve.

Abstract: A pneumatic paintball marker has, for example, a sleeve that controls the passage of air through the longitudinal barrel or opening within the marker. By sequentially filling separate chambers defined within the opening and the sleeve, the sleeve is able to translate axially through the opening in a sequential manner. When the sleeve is in a forward position, air is caused to be released through the barrel, propelling the paintball. A sear member engages the sleeve and prevents it from inadvertently moving to a forward position. Air filling the chambers returns the sleeve to the loading position.

Abstract: A pneumatic paintball marker has, for example, a sleeve that controls the passage of air through the longitudinal barrel or opening within the marker. By sequentially filling separate chambers defined within the opening and the sleeve, the sleeve is able to translate axially through the opening in a sequential manner. When the sleeve is in a forward position, air is caused to be released through the barrel, propelling the paintball. A sear member engages the sleeve and prevents it from inadvertently moving to a forward position. Air filling the chambers returns the sleeve to the loading position.

Abstract: A pneumatic paintball marker has, for example, a sleeve that controls the passage of air through the longitudinal barrel or opening within the marker. By sequentially filling separate chambers defined within the opening and the sleeve, the sleeve is able to translate axially through the opening in a sequential manner. When the sleeve is in a forward position, air is caused to be released through the barrel, propelling the paintball. A sear member engages the sleeve and prevents it from inadvertently moving to a forward position. Air filling the chambers returns the sleeve to the loading position.

Abstract: A pneumatic paintball marker has, for example, a sleeve that controls the passage of air through the longitudinal barrel or opening within the marker. By sequentially filling separate chambers defined within the opening and the sleeve, the sleeve is able to translate axially through the opening in a sequential manner. When the sleeve is in a forward position, air is caused to be released through the barrel, propelling the paintball. A sear member engages the sleeve and prevents it from inadvertently moving to a forward position. Air filling the chambers returns the sleeve to the loading position.

Abstract: The present invention contemplates a novel and unique pneumatic paintball marker with a variety of novel features the first being an on/off compressed air control valve at the front of the marker below the barrel adjacent to the inline pressure regulator. Major innovations have been made in reducing the size and weight of the body of the marker along with the construction of the new fuse bolt assembly consisting of just four components and only one moving part. An anti-chop eye electronic system insures the paintballs are in the proper position with the addition of rubber ball detents to hold the paintballs in place so that they will not roll out the barrel prior to firing the marker.

Abstract: A singlet telescope is provided for reshaping the laser beam to a larger or smaller diameter while maintaining the inherent quality of the beam. Applications for the singlet telescope include intercavity expansion to accommodate the damage thresh-old of various components, expansion of beams to match the size of different wavelengths for final collimation, and shrinking of beams to provide high irradiance for nonlinear processes such as optical parametric oscillation and frequency doubling, with the above applications usually requiring low power magnification or demagnification. Problems involving the utilization of these telescopes over wide temperature ranges and ghost reflections in which a light is reflected back to a pumping laser are minimized with the singlet construction, with the ghost reflections potentially creating damage of components including self-damage or breakdown of air, as well as damage to a Q-switched resonator which causes pre-lasing.

Abstract: A bonding head of the type having a bonding tool mounted in the bonding tool holder is provided with a pivotable wire clamp which is movable toward and away from the rear of the bonding tool. The wire clamp is pivotally movable to three distinct positions by a single solenoid. The wire clamp is opened and closed by a second solenoid. The solenoids are mounted on the pivot axis of the bonding tool holder in a manner which substantially prevents the shock force of actuation of the solenoid from being imparted into the bonding tool holder or the bonding tool during a bonding operation.