Abstract: Compositions and methods are provided for preventing or treating neoplastic disease in a mammalian subject. A composition is provided which comprises an enriched immune cell population reactive to a human endogenous retrovirus type E antigen on a tumor cell. A method of treating a neoplastic disease in a mammalian subject is provided which comprises administering to a mammalian subject a composition comprising an enriched immune cell population reactive to a human endogenous retrovirus type E antigen, in an amount effective to reduce or eliminate the neoplastic disease or to prevent its occurrence or recurrence.

Abstract: This invention generally relates to a composition comprising an enriched NK cell population. The invention further relates to a method of treating a solid tumor or a hyperproliferative disorder by administering the enriched NK cell population to a mammalian subject in need thereof.

Abstract: Signatures are generated for modules in a computer system. The signatures can be assembled into an integrity log. The signatures are compared with signatures in a database in an integrity validator. Once signatures are either validated or invalidated, a trust score can be generated. The trust score can then be used to determine whether the computer system should be granted access to a resource using a policy.

Abstract: A target machine can be verified prior to being granted access to a resource on a network by interrogating and analyzing digests of various elements of the target machine. The digests can be collected into an integrity report and provided to a Trust Scoring Service. The Trust Scoring Service receives the integrity report and compares the digests with signatures stored in a signature database. A trust score certificate can then be issued to the target machine. The Trust Scoring Service can include a Score Evaluation Server which can interact with a Kerberos Authentication Server and a Ticket Granting Server to embed a trust score within a Kerberos Ticket to enforce a richer set of access policies. The integrity of a web server can be verified and a Trust Score Certificate Logo can be displayed on a corresponding home page of a merchant. By clicking on the Trust Score Certificate Logo, a user can verify the integrity of the merchant's web servers prior to completing a transaction with the merchant.

Abstract: A method and system for verifying the integrity of virtual machines and for verifying the integrity of discrete elements of the virtual machines throughout the lifecycle of the virtual machines. A virtual machine manager capable of managing one or more virtual machine images is installed on a physical hardware platform. An integrity verification component can be communicatively coupled to the virtual machine manager and an integrity reference component so that the integrity verification component can compare digests of the virtual machine image or discrete virtual machine image elements to virtual machine integrity records accessible from the integrity reference component.

Abstract: A client platform can be verified prior to being granted access to a resource or service on a network by validating individual hardware and software components of the client platform. Digests are generated for the components of the client platform. The digests can be collected into an integrity report. An authenticator entity receives the integrity report and compares the digests with digests stored in either a local signature database, a global signature database in an integrity authority, or both. Alternatively, the digests can be collected and stored on a portable digest-collector dongle. Once digests are either validated or invalidated, an overall integrity/trust score can be generated. She overall integrity/trust score can be used to determine whether the client platform should be granted access to the resource on the network using a policy.

Abstract: A router includes a management module and a routing module. The routing module can be used to route data around a network. The management module can be used to manage the operation of the routing module, including generating an integrity report for the router, which can be used to generate a trust report for the router. The trust report can include an integrity/trust score for the router. The management module can control the routing module via a secure control interface.

Abstract: Signatures are generated for modules in a computer system. The signatures can be assembled into an integrity log. The signatures are compared with signatures in a database in an integrity validator. Once signatures are either validated or invalidated, a trust score can be generated. The trust score can then be used to determine whether the computer system should be granted access to a resource using a policy.

Abstract: Signatures are generated for modules in a computer system. The signatures can be assembled into an integrity log. The signatures are compared with signatures in a database in an integrity validator. Once signatures are either validated or invalidated, a trust score can be generated. The trust score can then be used to determine whether the computer system should be granted access to a resource using a policy.

Abstract: A router includes a management module and a routing module. The routing module can be used to route data around a network. The management module can be used to manage the operation of the routing module, including generating an integrity report for the router, which can be used to generate a trust report for the router. The trust report can include an integrity/trust score for the router. The management module can control the routing module via a secure control interface.

Abstract: A router includes a management module and a routing module. The routing module can be used to route data around a network. The management module can be used to manage the operation of the routing module, including generating an integrity report for the router, which can be used to generate a trust report for the router. The trust report can include an integrity/trust score for the router. The management module can control the routing module via a secure control interface.

Abstract: Compositions and methods are provided for preventing or treating neoplastic disease in a mammalian subject. A composition is provided which comprises an enriched immune cell population reactive to a human endogenous retrovirus type E antigen on a tumor cell. A method of treating a neoplastic disease in a mammalian subject is provided which comprises administering to a mammalian subject a composition comprising an enriched immune cell population reactive to a human endogenous retrovirus type E antigen, in an amount effective to reduce or eliminate the neoplastic disease or to prevent its occurrence or recurrence.

Abstract: Signatures are generated for modules in a computer system. The signatures can be assembled into an integrity log. The signatures are compared with signatures in a database in an integrity validator. Once signatures are either validated or invalidated, a trust score can be generated. The trust score can then be used to determine whether the computer system should be granted access to a resource using a policy.

Abstract: The invention generally relates to a composition comprising an enriched NK cell population. The invention further relates to a method of treating a solid tumor or a hyperproliferative disorder by administering the enriched NK cell population to a mammalian subject in need thereof.

Abstract: A method and system for verifying the integrity of virtual machines and for verifying the integrity of discrete elements of the virtual machines throughout the lifecycle of the virtual machines. A virtual machine manager capable of managing one or more virtual machine images is installed on a physical hardware platform. An integrity verification component can be communicatively coupled to the virtual machine manager and an integrity reference component so that the integrity verification component can compare digests of the virtual machine image or discrete virtual machine image elements to virtual machine integrity records accessible from the integrity reference component.

Abstract: Signatures are generated for modules in a computer system. The signatures can be assembled into an integrity log. The signatures are compared with signatures in a database in an integrity validator. Once signatures are either validated or invalidated, a trust score can be generated. The trust score can then be used to determine whether the computer system should be granted access to a resource using a policy.

Abstract: According to one embodiment of the invention, a method is provided for cooling heat-generating structure disposed in an environment having an ambient pressure. The heat-generating structure includes electronics. The method includes providing a coolant, reducing a pressure of the coolant to a subambient pressure at which the coolant has a boiling temperature less than a temperature of the heat-generating structure, and bringing the heat-generating structure and the coolant at the subambient pressure into contact with one another, so that the coolant boils and vaporizes to thereby absorb heat from the heat-generating structure. In a more particular embodiment the coolant is either pure water or pure methanol with an electrical resistivity level of greater than one million Ohms-cm. Further, in another particular embodiment the method includes filtering the coolant to maintain its purity above a particular level.

Abstract: Signatures are generated for modules in a computer system. The signatures can be assembled into an integrity log. The signatures are compared with signatures in a database in an integrity validator. Once signatures are either validated or invalidated, a trust score can be generated. The trust score can then be used to determine whether the computer system should be granted access to a resource using a policy.

Abstract: According to one embodiment of the invention, a cooling system for heat-generating structures comprises a plurality of heat exchangers, a structure which directs flow of the fluid coolant substantially in the form of a liquid to each of the plurality of heat exchangers, and a structure which reduces a pressure of the fluid coolant to a pressure at which the fluid coolant has a boiling temperature less than a temperature of the heat-generating structures. Each of the plurality of heat exchangers is in thermal communication with at least one of the heat-generating structures and has an inlet and an outlet. Thermal energy from the heat-generating structure causes the fluid coolant substantially in the form of a liquid to boil and vaporize in each of the plurality of heat exchangers so that the fluid coolant absorbs thermal energy from the heat-generating structure as the fluid coolant changes state.

Abstract: According to one embodiment of the invention, a cooling system for a heat-generating structure that is disposed in an environment having an ambient pressure comprises a fluid coolant and three structures. The first structure allows the heat generating structure to removably couple to the cooling system. The second structure reduces a pressure of the fluid coolant to a subambient pressure at which the fluid coolant has a boiling temperature less than a temperature of the heat-generating structure. The third structure directs a flow of the fluid coolant in the form of a liquid at the subambient pressure in a manner causing the fluid coolant to be brought into thermal communication with the heat-generating structure where heat from the heat-generating structure causes the fluid coolant in the form of the liquid to boil and vaporize so that the fluid coolant absorbs heat from the heat-generating structure as the fluid coolant changes state.